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Gene: MCMDC2 (minichromosome maintenance domain containing 2) Homo sapiens
Symbol: MCMDC2
Name: minichromosome maintenance domain containing 2
Description: Predicted to have DNA replication origin binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation; gamete generation; and meiosis I cell cycle process. Predicted to localize to the MCM complex and nucleus; INTERACTS WITH 17beta-estradiol; aflatoxin B1; aflatoxin M1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C8orf45; FLJ25692; MCM domain-containing protein 2; MCM domain-containing protein C8orf45; minichromosome maintenance complex component-like; minichromosome maintenance domain-containing protein 2; uncharacterized protein C8orf45
Mus musculus (house mouse) : Mcmdc2 (minichromosome maintenance domain containing 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mcmdc2 (minichromosome maintenance domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcmdc2 (minichromosome maintenance domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MCMDC2 (minichromosome maintenance domain containing 2)
Canis lupus familiaris (dog) : MCMDC2 (minichromosome maintenance domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcmdc2 (minichromosome maintenance domain containing 2)
Sus scrofa (pig) : MCMDC2 (minichromosome maintenance domain containing 2)
Chlorocebus sabaeus (African green monkey) : MCMDC2 (minichromosome maintenance domain containing 2)
Heterocephalus glaber (naked mole-rat) : Mcmdc2 (minichromosome maintenance domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl866,870,749 - 66,922,048 (+)Ensembl
GRCh38866,870,757 - 66,926,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37867,782,984 - 67,834,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36867,948,884 - 67,976,570 (+)NCBINCBI36hg18NCBI36
Celera863,776,478 - 63,827,777 (+)NCBI
Cytogenetic Map8q13.1NCBI
HuRef863,275,571 - 63,326,869 (+)NCBIHuRef
CHM1_1867,837,961 - 67,889,304 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MCMDC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605856
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.