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ONTOLOGY REPORT - ANNOTATIONS

Term:polyspecific organic cation:proton antiporter activity
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Accession:GO:0140968 term browser browse the term
Definition:Enables the transfer of various organic cations in exchange for a proton, according to the reaction: H+(out) + organic cation(in) = H+(in) + organic cation(out). The transported substrates are usually toxic molecules, drugs and xenobiotics.
Synonyms:xref: TC:2.A.66.1.20

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polyspecific organic cation:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G D ALDH3A2 aldehyde dehydrogenase 3 family member A2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:40,515,768...40,641,377
Ensembl chr 5:40,515,030...40,641,463 		JBrowse link
G S LOC101967932 multidrug and toxin extrusion protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936881:222,722...260,719
Ensembl chrNW_004936881:222,759...260,719 		JBrowse link
G S LOC101970809 multidrug and toxin extrusion protein 2-like enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936881:168,930...221,399 JBrowse link
G P LOC102157639 multidrug and toxin extrusion protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr12:59,977,028...60,020,170 JBrowse link
G N Slc47a1 solute carrier family 47 member 1 enables ISO PMID:17047166
(PMID:16330770), (PMID:17509534)
(PMID:16641166)		 UniProt PMID:16330770 PMID:16641166 PMID:17047166 PMID:17509534 RGD:2316964 NCBI chrNW_004624849:5,775,925...5,831,941
Ensembl chrNW_004624849:5,776,180...5,830,871 		JBrowse link
G G SLC47A1 solute carrier family 47 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:18,124,681...18,168,702
Ensembl chr16:18,125,252...18,169,552 		JBrowse link
G P SLC47A1 solute carrier family 47 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr12:60,021,176...60,114,488
Ensembl chr12:60,021,188...60,056,938 		JBrowse link
G D SLC47A1 solute carrier family 47 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946 		JBrowse link
G B SLC47A1 solute carrier family 47 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:31,532,821...31,577,523
Ensembl chr17:36,695,965...36,741,618 		JBrowse link
G R Slc47a1 solute carrier family 47 member 1 enables IDA
ISO
IEA		 PMID:17047166
(PMID:16641166)
GO_REF:0000107
(PMID:16330770), (PMID:17509534)		 RGD
Ensembl		 PMID:16330770 PMID:16641166 PMID:17509534 PMID:17047166 GO_REF:0000107, RGD:2316964 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G M Slc47a1 solute carrier family 47, member 1 enables ISO
IDA		 (PMID:16641166) GO_Central
UniProt		 PMID:16641166 GO_REF:0000096 GO_REF:0000119 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171 		JBrowse link
G H SLC47A1 solute carrier family 47 member 1 enables IDA
IEA		 (PMID:16330770), (PMID:17509534) UniProt
Ensembl		 PMID:16330770 PMID:17509534 GO_REF:0000107 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034 		JBrowse link
G G SLC47A2 solute carrier family 47 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr16:18,240,876...18,281,634
Ensembl chr16:18,242,392...18,279,930 		JBrowse link
G P SLC47A2 solute carrier family 47 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr12:59,919,553...59,935,895
Ensembl chr12:59,920,770...59,935,894 		JBrowse link
G D SLC47A2 solute carrier family 47 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:40,491,306...40,515,430
Ensembl chr 5:40,491,933...40,540,136 		JBrowse link
G B SLC47A2 solute carrier family 47 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr17:31,412,990...31,454,667
Ensembl chr17:36,560,881...36,599,133 		JBrowse link
G R Slc47a2 solute carrier family 47 member 2 enables ISO (PMID:16807400)
(PMID:17715386)		 RGD PMID:16807400 PMID:17715386 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G M Slc47a2 solute carrier family 47, member 2 enables ISO
IDA		 (PMID:17715386) GO_Central
UniProt		 PMID:17715386 GO_REF:0000119 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686 		JBrowse link
G H SLC47A2 solute carrier family 47 member 2 enables IDA (PMID:16807400) UniProt PMID:16807400 NCBI chr17:19,678,317...19,718,979
Ensembl chr17:19,678,288...19,718,979 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 200960
    transporter activity 11843
      transmembrane transporter activity 10811
        monoatomic ion transmembrane transporter activity 7251
          active monoatomic ion transmembrane transporter activity 2524
            polyspecific organic cation:proton antiporter activity 19
Path 2
Term Annotations click to browse term
  molecular_function 200960
    transporter activity 11843
      transmembrane transporter activity 10811
        monoatomic ion transmembrane transporter activity 7251
          monoatomic cation transmembrane transporter activity 6093
            proton transmembrane transporter activity 1538
              polyspecific organic cation:proton antiporter activity 19
paths to the root