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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to epidermal growth factor stimulus
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Accession:GO:0071364 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: cellular response to EGF stimulus

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cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chr10:16,296,350...16,369,561
Ensembl chr10:16,297,502...16,369,220 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:30514904)
(MGI:5292318|PMID:21712384)		 UniProt PMID:21712384 PMID:30514904 MGI:5292318 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr10:104,098,275...104,144,043
Ensembl chr10:104,098,402...104,135,791 		JBrowse link
G BAG4 BAG cochaperone 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,198,547...36,231,550
Ensembl chr 8:36,198,811...36,231,828 		JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chr16:72,986,476...73,065,358
Ensembl chr16:72,986,490...73,067,001 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:20539009 RGD:6483081 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO (PMID:19116644) MGI PMID:19116644 NCBI chr26:37,605,891...37,622,302
Ensembl chr26:37,604,412...37,622,083 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 PMID:26324884 RGD:11568705 RGD:11570555 NCBI chr 1:8,408,560...8,410,564 JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652 		JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:2016852 RGD:2316227 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G CRIPTO cripto, EGF-CFC family member involved_in ISO (PMID:17720976) UniProt PMID:17720976 NCBI chr22:7,993,724...8,000,935
Ensembl chr22:7,997,383...8,000,629 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in ISO PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 4:38,171,320...38,224,275
Ensembl chr 4:38,173,026...38,224,231 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DUSP22 dual specificity phosphatase 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:71,798,515...71,855,642
Ensembl chr17:71,799,014...71,855,601 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:62,622,667...62,637,129
Ensembl chr16:62,622,663...62,637,127 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 involved_in ISO (PMID:9852145) UniProt PMID:9852145 NCBI chr17:1,626,701...1,630,445
Ensembl chr17:1,627,901...1,630,150 		JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 involved_in ISO (PMID:27134172) UniProt PMID:27134172 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 acts_upstream_of_or_within ISO (PMID:8702723) MGI PMID:8702723 NCBI chr10:97,099,090...98,281,697 JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8603605 RGD:151665808 NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514 		JBrowse link
G FOXC1 forkhead box C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,533,048...70,536,555
Ensembl chr17:70,534,821...70,536,476 		JBrowse link
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:48,287,589...48,483,135
Ensembl chr18:48,287,579...48,483,552 		JBrowse link
G GIT1 GIT ArfGAP 1 ISO RGD PMID:18523162 RGD:13513208 NCBI chr16:23,313,629...23,329,665
Ensembl chr16:23,315,439...23,329,469 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 RGD:13792711 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chr11:50,397,173...50,403,192
Ensembl chr11:50,396,888...50,400,802 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chr 5:1,698,787...1,704,205
Ensembl chr 5:1,698,978...1,701,972 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,171,059...1,192,241
Ensembl chr16:1,170,899...1,191,965 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 involved_in ISO (MGI:5430891|PMID:17563371)
(PMID:17563371), (PMID:26242911)		 BHF-UCL PMID:17563371 PMID:26242911 MGI:5430891 NCBI chr29:9,363,273...9,485,644
Ensembl chr29:9,362,926...9,485,526 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:10889193 RGD:12910555 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:42,620,401...42,631,932
Ensembl chr26:42,621,084...42,631,822 		JBrowse link
G LOC103216393 paired box protein Pax-2 ISO RGD PMID:11262416 RGD:2316756 NCBI chr 9:93,763,975...93,847,180 JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B involved_in ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOC103247994 DNA-binding protein inhibitor ID-1 ISO RGD PMID:7623812 RGD:9686118 NCBI chr 2:36,008,660...36,009,880
Ensembl chr 2:36,008,636...36,010,017 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:8246947 RGD:401976489 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:53,397,380...53,410,596 JBrowse link
G MCM7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G MED1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO RGD PMID:11769575 RGD:2324971 NCBI chr 1:981,515...1,018,242 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:7524476 RGD:10059620 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G NCL nucleolin acts_upstream_of_or_within ISO (PMID:8702723) MGI PMID:8702723 NCBI chr10:117,478,279...117,487,810 JBrowse link
G NCL nucleolin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:117,477,904...117,486,774 JBrowse link
G PDE8A phosphodiesterase 8A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:3,214,183...3,367,051
Ensembl chr29:3,213,165...3,367,571 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107
G PLCG1 phospholipase C gamma 1 involved_in ISO (PMID:17229814)
(PMID:22454520)		 UniProt
BHF-UCL		 PMID:17229814 PMID:22454520 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLCG1 phospholipase C gamma 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:22,604,043...22,637,967 JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:71,285,917...71,389,645
Ensembl chr21:71,285,736...71,389,926 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:2005883 RGD:10002731 NCBI chr 4:81,249,851...81,371,486
Ensembl chr 4:81,249,805...81,370,453 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in ISO (PMID:18716062) BHF-UCL PMID:18716062 NCBI chr 8:45,043,381...45,047,054
Ensembl chr 8:45,043,393...45,046,978 		JBrowse link
G SNX6 sorting nexin 6 ISO RGD PMID:18523162 RGD:13513208 NCBI chr24:11,389,436...11,433,126
Ensembl chr24:11,388,329...11,433,545 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G SYAP1 synapse associated protein 1 involved_in ISO (MGI:6114863|PMID:23300339)
(PMID:23300339)		 UniProt PMID:23300339 MGI:6114863 NCBI chr  X:15,150,457...15,206,076
Ensembl chr  X:15,150,502...15,206,554 		JBrowse link
G VIL1 villin 1 involved_in ISO (PMID:17229814) UniProt PMID:17229814 NCBI chr10:104,311,048...104,350,846
Ensembl chr10:104,320,074...104,347,289 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:34,011,073...34,013,665
Ensembl chr 6:34,011,031...34,013,870 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in ISO (PMID:20166898) UniProt PMID:20166898 NCBI chr24:46,000,222...46,005,455
Ensembl chr24:45,999,623...46,006,218 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:64,019,633...64,022,301
Ensembl chr14:64,019,418...64,026,281 		JBrowse link
G ZPR1 ZPR1 zinc finger involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,144,247...108,153,533
Ensembl chr 1:108,144,609...108,153,480 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17093
    response to stimulus 8707
      response to endogenous stimulus 1880
        response to growth factor 849
          response to epidermal growth factor 69
            cellular response to epidermal growth factor stimulus 61
paths to the root