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ONTOLOGY REPORT - ANNOTATIONS


Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus



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response to epidermal growth factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot2 acyl-CoA thioesterase 2 IEP murine EGF RGD PMID:18388199 RGD:2315857 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 IEP RGD PMID:9473334 RGD:2314149 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Igf1 insulin-like growth factor 1 IEP RGD PMID:2003595 RGD:12910130 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1r1 interleukin 1 receptor type 1 IEP RGD PMID:9233842 RGD:8662880 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
ISS
(PMID:18794356)
GO_REF:0000024
RGD
UniProt
PMID:18794356 GO_REF:0000024 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO
ISS
(PMID:18794356), (PMID:21968647)
GO_REF:0000024
RGD
UniProt
PMID:18794356 PMID:21968647 GO_REF:0000024 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:1333984 RGD:8547845 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sftpa1 surfactant protein A1 IEP RGD PMID:19781387 RGD:4143468 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
JBrowse link
G Sftpb surfactant protein B IEP RGD PMID:19781387 RGD:4143468 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS
(PMID:18794356)
GO_REF:0000024
RGD
UniProt
PMID:18794356 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IEP RGD PMID:10209028 RGD:2306208 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 IEP RGD PMID:17855387 RGD:2306203 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Becn1 beclin 1 IEP RGD PMID:20539009 RGD:6483081 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP RGD PMID:10659854 RGD:2303528 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Cfl1 cofilin 1 IEP
IMP
RGD PMID:26324884 PMID:23704350 RGD:11568705, RGD:11570555 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IEP RGD PMID:16033771 RGD:11341689 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Col1a1 collagen type I alpha 1 chain IEP RGD PMID:2016852 RGD:2316227 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IDA PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dab2ip DAB2 interacting protein involved_in IDA PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dusp22 dual specificity phosphatase 22 involved_in ISO (PMID:20018849) RGD PMID:20018849 NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036)
(MGI:6101044|PMID:28759036)
RGD PMID:28759036 MGI:6101044 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:9852145)
UniProt
RGD
PMID:9852145 GO_REF:0000024 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Egfr epidermal growth factor receptor involved_in IDA PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in ISO
ISS
(PMID:27134172)
GO_REF:0000024
RGD
UniProt
PMID:27134172 GO_REF:0000024 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 acts_upstream_of_or_within ISO (MGI:82360|PMID:8702723) RGD PMID:8702723 MGI:82360 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP RGD PMID:15556944 RGD:9685545 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:8603605 RGD:151665808 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:16492674) RGD PMID:16492674 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 involved_in ISO (PMID:19509291) RGD PMID:19509291 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345
JBrowse link
G Git1 GIT ArfGAP 1 IDA RGD PMID:18523162 RGD:13513208 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:24018045 RGD:13792711 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP RGD PMID:1908848 RGD:2317845 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 IEP RGD PMID:3062579 RGD:10041005 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IEP RGD PMID:7623812 RGD:9686118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IEP RGD PMID:8070348 RGD:12911020 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:21712384) RGD PMID:21712384 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 involved_in ISO (PMID:17563371), (PMID:26242911)
(MGI:5430891|PMID:17563371)
RGD PMID:17563371 PMID:26242911 MGI:5430891 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Ireb2 iron responsive element binding protein 2 IDA RGD PMID:10889193 RGD:12910555 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein involved_in ISO (PMID:26242911) RGD PMID:26242911 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 involved_in ISO (PMID:10791971) RGD PMID:10791971 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 IEP RGD PMID:19821535 RGD:2316313 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16314496)
UniProt
RGD
PMID:16314496 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming IEP RGD PMID:11769575 RGD:2324971 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP RGD PMID:7524476 RGD:10059620 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncl nucleolin acts_upstream_of_or_within ISO (MGI:82360|PMID:8702723) RGD PMID:8702723 MGI:82360 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Pax2 paired box 2 IEP RGD PMID:11262416 RGD:2316756 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pde8a phosphodiesterase 8A involved_in IBA
ISO
PMID:21873635
(MGI:5484722|PMID:23509299)
(PMID:23509299)
RGD PMID:23509299 PMID:21873635 MGI:5484722, RGD:13792537 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:22454520) RGD PMID:22454520 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Plcg1 phospholipase C, gamma 1 involved_in ISO
ISS
(PMID:17229814), (PMID:22454520)
GO_REF:0000024
RGD
UniProt
PMID:17229814 PMID:22454520 GO_REF:0000024 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IEP RGD PMID:10620493 RGD:10002737 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISS
ISO
GO_REF:0000024
(PMID:28074573)
UniProt
RGD
PMID:28074573 GO_REF:0000024 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 involved_in IBA
ISO
PMID:21873635
(PMID:27134172)
RGD PMID:27134172 PMID:21873635 RGD:13792537 NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:8603605 RGD:151665808 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Rasa1 RAS p21 protein activator 1 IDA RGD PMID:2005883 RGD:10002731 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18716062) RGD PMID:18716062 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snx6 sorting nexin 6 IDA RGD PMID:18523162 RGD:13513208 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285125|PMID:21512138)
UniProt
RGD
PMID:21512138 GO_REF:0000024 MGI:5285125 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in IDA PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO (PMID:23300339)
(MGI:6114863|PMID:23300339)
RGD PMID:23300339 MGI:6114863 NCBI chr  X:31,792,180...31,826,672
Ensembl chr  X:31,792,193...31,826,667
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 involved_in ISO (PMID:17720976) RGD PMID:17720976 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:17229814) RGD PMID:17229814 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO
GO_REF:0000024
(PMID:20166898)
UniProt
RGD
PMID:20166898 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20166898)
UniProt
RGD
PMID:20166898 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (PMID:20166898) RGD PMID:20166898 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
G Zpr1 ZPR1 zinc finger involved_in ISO (PMID:9852145) RGD PMID:9852145 NCBI chr 8:46,564,898...46,574,719
Ensembl chr 8:46,565,146...46,574,719
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    response to stimulus 10209
      response to endogenous stimulus 2085
        response to epidermal growth factor 68
          cellular response to epidermal growth factor stimulus 58
Path 2
Term Annotations click to browse term
  biological_process 18734
    response to stimulus 10209
      response to chemical 6156
        response to organic substance 3899
          response to growth factor 867
            response to epidermal growth factor 68
              cellular response to epidermal growth factor stimulus 58
paths to the root