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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of isotype switching to IgG isotypes
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Accession:GO:0048302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: regulation of class switch recombination to IgG isotypes;   regulation of class switching to IgG isotypes;   regulation of isotype switch recombination to IgG isotypes

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regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chrNW_004624901:1,274,753...1,288,783
Ensembl chrNW_004624901:1,274,840...1,287,861 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004624774:1,245,587...1,353,253
Ensembl chrNW_004624774:1,303,773...1,353,253 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004624875:97,048...154,420
Ensembl chrNW_004624875:97,670...151,080 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12882831) TreeGrafter
MGI		 PMID:12882831 GO_REF:0000118 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704 		JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004624782:13,387,155...13,390,153
Ensembl chrNW_004624782:13,387,376...13,389,740 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004624800:2,653,381...2,709,261
Ensembl chrNW_004624800:2,653,732...2,707,161 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      production of molecular mediator of immune response 224
        immunoglobulin production 108
          regulation of immunoglobulin production 78
            regulation of isotype switching 38
              regulation of isotype switching to IgG isotypes 17
                negative regulation of isotype switching to IgG isotypes 0
                positive regulation of isotype switching to IgG isotypes 13
Path 2
Term Annotations click to browse term
  biological_process 15093
    metabolic process 9085
      organic substance metabolic process 8667
        organic cyclic compound metabolic process 4858
          nucleobase-containing compound metabolic process 4436
            nucleic acid metabolic process 3987
              DNA metabolic process 842
                DNA recombination 296
                  somatic cell DNA recombination 75
                    somatic diversification of immune receptors via germline recombination within a single locus 75
                      somatic recombination of immunoglobulin gene segments 63
                        somatic recombination of immunoglobulin genes involved in immune response 55
                          isotype switching 55
                            isotype switching to IgG isotypes 18
                              regulation of isotype switching to IgG isotypes 17
                                negative regulation of isotype switching to IgG isotypes 0
                                positive regulation of isotype switching to IgG isotypes 13
paths to the root