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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylethanolamine metabolic process
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Accession:GO:0046337 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.
Synonyms:exact_synonym: phosphatidylethanolamine metabolism


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phosphatidylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPC lipase C, hepatic type ISO RGD PMID:2223857 RGD:1600650 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPIN1 lipin 1 involved_in IDA (PMID:23426360), (PMID:31695197) UniProt PMID:23426360 PMID:31695197 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G PLA2G10 phospholipase A2 group X involved_in IEA
IDA		 (PMID:12359733) Ensembl
UniProt		 PMID:12359733 GO_REF:0000107 NCBI chr16:14,672,548...14,701,850
Ensembl chr16:14,672,548...14,694,308 		JBrowse link
G PLA2G10BP phospholipase A2 group XB, pseudogene involved_in IDA
IEA		 (PMID:12359733) UniProt
Ensembl		 PMID:12359733 GO_REF:0000107 NCBI chr16:14,709,058...14,742,495 JBrowse link
G PLA2G2A phospholipase A2 group IIA involved_in IDA (PMID:25082876) UniProt PMID:25082876 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLA2G2D phospholipase A2 group IID involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:20,111,939...20,119,536
Ensembl chr 1:20,111,939...20,119,566 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IDA (PMID:28947740) UniProt PMID:28947740 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508 		JBrowse link
N-acylphosphatidylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B involved_in ISS UniProt GO_REF:0000024 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963 		JBrowse link
G NAAA N-acylethanolamine acid amidase involved_in IDA (PMID:22825852) UniProt PMID:22825852 NCBI chr 4:75,910,655...75,941,013
Ensembl chr 4:75,913,660...75,941,013 		JBrowse link
G NAPEPLD N-acyl phosphatidylethanolamine phospholipase D involved_in IDA
IEA
IBA		 (PMID:25684574) UniProt
TreeGrafter
GO_Central
Ensembl		 PMID:25684574 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:103,099,776...103,150,001
Ensembl chr 7:103,099,776...103,149,560 		JBrowse link
G PLA2G4E phospholipase A2 group IVE involved_in IDA
IEA		 (PMID:29447909) UniProt
Ensembl		 PMID:29447909 GO_REF:0000107 NCBI chr15:41,981,582...42,050,703
Ensembl chr15:41,981,394...42,051,190 		JBrowse link
G PLAAT1 phospholipase A and acyltransferase 1 involved_in IDA
IBA
IEA		 (PMID:22825852), (PMID:27623847) UniProt
GO_Central		 PMID:22825852 PMID:27623847 GO_REF:0000033 GO_REF:0000117 NCBI chr 3:193,240,606...193,281,426
Ensembl chr 3:193,241,128...193,277,738 		JBrowse link
G PLAAT2 phospholipase A and acyltransferase 2 involved_in IDA
IBA
IEA		 (PMID:22825852) UniProt
GO_Central		 PMID:22825852 GO_REF:0000033 GO_REF:0000117 NCBI chr11:63,552,770...63,565,070
Ensembl chr11:63,552,770...63,563,379 		JBrowse link
G PLAAT3 phospholipase A and acyltransferase 3 involved_in IDA
IBA
IEA		 (PMID:22825852) UniProt
GO_Central		 PMID:22825852 GO_REF:0000033 GO_REF:0000117 NCBI chr11:63,574,462...63,616,927
Ensembl chr11:63,573,195...63,616,883 		JBrowse link
G PLAAT4 phospholipase A and acyltransferase 4 involved_in IDA
IBA
IEA		 (PMID:22825852) UniProt
GO_Central		 PMID:22825852 GO_REF:0000033 GO_REF:0000117 NCBI chr11:63,536,808...63,546,458
Ensembl chr11:63,536,808...63,546,462 		JBrowse link
G PLAAT5 phospholipase A and acyltransferase 5 involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA		 (PMID:22825852)
(PMID:19000777)		 UniProt
TreeGrafter
GO_Central
MGI		 PMID:19000777 PMID:22825852 GO_REF:0000033 GO_REF:0000117 GO_REF:0000118 NCBI chr11:63,461,404...63,491,167
Ensembl chr11:63,461,404...63,491,194 		JBrowse link
phosphatidylethanolamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 involved_in IEA
IDA
IBA		 (PMID:10191259) UniProt
TreeGrafter
GO_Central		 PMID:10191259 GO_REF:0000033 GO_REF:0000041 GO_REF:0000118 NCBI chr 1:111,139,499...111,185,104
Ensembl chr 1:111,139,479...111,185,104 		JBrowse link
G CHKA choline kinase alpha involved_in IDA
IBA
IEA		 (PMID:19915674) UniProt
GO_Central		 PMID:19915674 GO_REF:0000033 GO_REF:0000041 NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444 		JBrowse link
G CHKB choline kinase beta involved_in IEA
IBA
IDA		 (PMID:19915674) UniProt
GO_Central		 PMID:19915674 GO_REF:0000033 GO_REF:0000041 NCBI chr22:50,578,963...50,582,849
Ensembl chr22:50,578,959...50,601,455 		JBrowse link
G ETNK1 ethanolamine kinase 1 involved_in IEA
IBA
IDA		 (PMID:11044454) UniProt
GO_Central		 PMID:11044454 GO_REF:0000033 GO_REF:0000041 NCBI chr12:22,625,171...22,690,665
Ensembl chr12:22,625,075...22,690,665 		JBrowse link
G ETNK2 ethanolamine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16861741) Ensembl
TreeGrafter
MGI
GO_Central
UniProt		 PMID:16861741 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:204,131,062...204,152,044
Ensembl chr 1:204,131,062...204,152,044 		JBrowse link
G PCYT2 phosphate cytidylyltransferase 2, ethanolamine involved_in IMP
IEA
IBA		 (PMID:31637422) UniProt
TreeGrafter
GO_Central
InterPro
Ensembl		 PMID:31637422 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr17:81,900,958...81,911,399
Ensembl chr17:81,900,958...81,911,432 		JBrowse link
G PISD phosphatidylserine decarboxylase involved_in IMP
IEA
IBA		 (PMID:30488656), (PMID:30858161) UniProt
TreeGrafter
GO_Central		 PMID:30488656 PMID:30858161 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 NCBI chr22:31,618,491...31,662,564
Ensembl chr22:31,618,491...31,662,221 		JBrowse link
G SELENOI selenoprotein I involved_in IEA
IBA
IDA
IMP		 (PMID:17132865)
(PMID:28052917), (PMID:29500230)		 UniProt
GO_Central
HGNC		 PMID:17132865 PMID:28052917 PMID:29500230 GO_REF:0000033 GO_REF:0000041 NCBI chr 2:26,346,143...26,395,885
Ensembl chr 2:26,308,547...26,395,885 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in IMP
IEA		 (PMID:19523918) UniProt
TreeGrafter		 PMID:19523918 GO_REF:0000118 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168 		JBrowse link
phosphatidylethanolamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G15 phospholipase A2 group XV involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:68,245,373...68,261,058
Ensembl chr16:68,245,304...68,261,058 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISS UniProt GO_REF:0000024 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PLB1 phospholipase B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:28,496,060...28,644,142
Ensembl chr 2:28,457,145...28,644,142 		JBrowse link
G PNPLA8 patatin like phospholipase domain containing 8 involved_in IDA (PMID:15695510) UniProt PMID:15695510 NCBI chr 7:108,470,417...108,528,178
Ensembl chr 7:108,470,417...108,569,666 		JBrowse link
regulation of phosphatidylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid involved_in
acts_upstream_of		 IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19654
    metabolic process 12453
      cellular metabolic process 10633
        cellular lipid metabolic process 1118
          glycerolipid metabolic process 433
            glycerophospholipid metabolic process 323
              phosphatidylethanolamine metabolic process 31
                N-acylphosphatidylethanolamine metabolic process 9
                negative regulation of phosphatidylethanolamine metabolic process 0
                phosphatidyl-N-monomethylethanolamine metabolic process + 0
                phosphatidylethanolamine biosynthetic process + 10
                phosphatidylethanolamine catabolic process 4
                positive regulation of phosphatidylethanolamine metabolic process 0
                regulation of phosphatidylethanolamine metabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 19654
    metabolic process 12453
      cellular metabolic process 10633
        phosphorus metabolic process 1985
          phosphate-containing compound metabolic process 1953
            phospholipid metabolic process 417
              glycerophospholipid metabolic process 323
                phosphatidylethanolamine metabolic process 31
                  N-acylphosphatidylethanolamine metabolic process 9
                  negative regulation of phosphatidylethanolamine metabolic process 0
                  phosphatidyl-N-monomethylethanolamine metabolic process + 0
                  phosphatidylethanolamine biosynthetic process + 10
                  phosphatidylethanolamine catabolic process 4
                  positive regulation of phosphatidylethanolamine metabolic process 0
                  regulation of phosphatidylethanolamine metabolic process + 1
paths to the root