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Gene: CHKB (choline kinase beta) Homo sapiens
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Symbol: CHKB
Name: choline kinase beta
Description: Exhibits choline kinase activity and ethanolamine kinase activity. Involved in phosphatidylethanolamine biosynthetic process. Predicted to localize to cytosol. Implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHETK; CHKL; choline kinase-like protein; choline/ethanolamine kinase; choline/ethanolamine kinase beta; CK; CKB; CKEKB; EK; EKB; ethanolamine kinase beta; MDCMC
Orthologs:
Mus musculus (house mouse) : Chkb (choline kinase beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chkb (choline kinase beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chkb (choline kinase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : CHKB (choline kinase beta)
Canis lupus familiaris (dog) : CHKB (choline kinase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chkb (choline kinase beta)
Sus scrofa (pig) : CHKB (choline kinase beta)
Chlorocebus sabaeus (African green monkey) : CHKB (choline kinase beta)
Heterocephalus glaber (naked mole-rat) : Chkb (choline kinase beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2250,578,949 - 50,601,455 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2250,578,959 - 50,601,455 (-)EnsemblGRCh38hg38GRCh38
GRCh382250,578,963 - 50,582,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372251,017,387 - 51,021,428 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,364,253 - 49,368,260 (-)NCBINCBI36hg18NCBI36
Celera2234,893,420 - 34,897,461 (-)NCBI
Cytogenetic Map22q13.33NCBI
HuRef2233,908,386 - 33,912,427 (-)NCBIHuRef
CHM1_12250,976,120 - 50,980,161 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CHKB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604071
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.