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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondria-associated endoplasmic reticulum membrane contact site
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Accession:GO:0044233 term browser browse the term
Definition:A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
Synonyms:exact_synonym: ER-mitochondrion membrane contact site;   endoplasmic-reticulum-mitochondrion membrane contact site;   mitochondria-associated ER membrane;   mitochondria-endoplasmic reticulum (ER) contact
 related_synonym: MAM;   Mitochondria-associated Membrane


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mitochondria-associated endoplasmic reticulum membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 located_in ISO
IEA		 (PMID:23455425)
GO_REF:0000107		 RGD
Ensembl		 PMID:23455425 GO_REF:0000107 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 located_in ISO
ISS
IEA		 (PMID:27995898)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:27995898 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A is_active_in
located_in		 ISO
IEA		 (PMID:39116259)
GO_REF:0000107		 RGD
Ensembl		 PMID:39116259 GO_REF:0000107 NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Atg14 autophagy related 14 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Atg5 autophagy related 5 located_in IEA
ISO		 GO_REF:0000107
(PMID:23455425)		 Ensembl
RGD		 PMID:23455425 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 located_in ISO (PMID:31206022) RGD PMID:31206022 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcl2l10 Bcl2-like 10 located_in ISS
ISO		 GO_REF:0000024
(PMID:27995898)		 UniProt
RGD		 PMID:27995898 GO_REF:0000024 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Canx calnexin located_in ISO
IEA		 (PMID:23455425)
GO_REF:0000107		 RGD
Ensembl		 PMID:23455425 GO_REF:0000107 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Clcc1 chloride channel CLIC-like 1 located_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:31653868)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:31653868 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 is_active_in
located_in		 ISO
IEA		 (PMID:39116259)
GO_REF:0000107		 RGD
Ensembl		 PMID:39116259 GO_REF:0000107 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 located_in ISO (PMID:23510452) RGD PMID:23510452 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Pdzd8 PDZ domain containing 8 located_in
is_active_in		 ISO
IBA		 (PMID:29097544)
GO_REF:0000033		 RGD
GO_Central		 PMID:29097544 GO_REF:0000033 NCBI chr 1:258,449,218...258,506,828
Ensembl chr 1:258,449,218...258,506,828 		JBrowse link
G Rab32 RAB32, member RAS oncogene family located_in ISO (PMID:25767741) RGD PMID:25767741 NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934 		JBrowse link
G Rab38 RAB38, member RAS oncogene family located_in ISO (PMID:25767741) RGD PMID:25767741 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Selenon selenoprotein N is_active_in ISO (PMID:32661288) RGD PMID:32661288 NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059 		JBrowse link
G Serac1 serine active site containing 1 located_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727 		JBrowse link
G Stx17 syntaxin 17 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr 5:62,446,138...62,506,108
Ensembl chr 5:62,446,187...62,504,451 		JBrowse link
G Tmem41b transmembrane protein 41B located_in ISO
ISS		 (PMID:30352685)
GO_REF:0000024		 RGD
UniProt		 PMID:30352685 GO_REF:0000024 NCBI chr 1:164,012,585...164,026,967
Ensembl chr 1:164,012,592...164,026,933 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 is_active_in ISO (PMID:22045338), (PMID:27502484) RGD PMID:22045338 PMID:27502484 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 located_in
is_active_in		 ISO
ISS		 (PMID:31735293)
GO_REF:0000024
(PMID:22045338)		 RGD
UniProt		 PMID:22045338 PMID:31735293 GO_REF:0000024 NCBI chr 3:69,754,937...69,762,587
Ensembl chr 3:69,754,939...69,762,587 		JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 located_in IEA
ISO		 GO_REF:0000107
(PMID:31206022)		 Ensembl
RGD		 PMID:31206022 GO_REF:0000107 NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A located_in ISO (PMID:30093493) RGD PMID:30093493 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Zfyve1 zinc finger FYVE-type containing 1 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr 6:103,184,938...103,234,111
Ensembl chr 6:103,184,938...103,234,039 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle membrane contact site 48
        mitochondria-associated endoplasmic reticulum membrane contact site 24
          ERMES complex 0
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        organelle membrane contact site 48
          mitochondria-associated endoplasmic reticulum membrane contact site 24
            ERMES complex 0
paths to the root