Gene: Serac1 (serine active site containing 1) Rattus norvegicus
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Symbol: Serac1
Name: serine active site containing 1
Description: INVOLVED IN extracellular matrix organization (ortholog); intracellular cholesterol transport (ortholog); phosphatidylglycerol acyl-chain remodeling (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); Deafness (ortholog); dystonia (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular matrix (ortholog); mitochondria-associated endoplasmic reticulum membrane (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); aflatoxin B1 (ortholog); antirheumatic drug (ortholog)
AGR Description: Predicted to be involved in extracellular matrix organization, intracellular cholesterol transport, and phosphatidylglycerol acyl-chain remodeling; predicted to localize to the cytoplasm, extracellular matrix, and mitochondria-associated endoplasmic reticulum membrane; orthologous to human SERAC1 (serine active site containing 1).
Merged Description: Predicted to be involved in extracellular matrix organization, intracellular cholesterol transport, and phosphatidylglycerol acyl-chain remodeling; predicted to localize to the cytoplasm, extracellular matrix, and mitochondria-associated endoplasmic reticulum membrane; orthologous to human SERAC1 (serine active site containing 1); INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); aflatoxin B1 (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499015; RGD1565064; similar to serine active site containing 1
Orthologs:
Homo sapiens (human) : SERAC1 (serine active site containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Serac1 (serine active site containing 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serac1 (serine active site containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERAC1 (serine active site containing 1)
Canis lupus familiaris (dog) : SERAC1 (serine active site containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serac1 (serine active site containing 1)
Sus scrofa (pig) : SERAC1 (serine active site containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0146,934,499 - 46,978,264 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0148,237,998 - 48,280,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4140,824,256 - 40,853,956 (-)NCBIRGSC3.4rn4RGSC3.4
Celera142,307,174 - 42,346,125 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Serac1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565064
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.