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ONTOLOGY REPORT - ANNOTATIONS


Term:organelle membrane contact site
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Accession:GO:0044232 term browser browse the term
Definition:A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
Synonyms:exact_synonym: MCS
 narrow_synonym: inter-organelle junction;   interorganelle junction


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organelle membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esyt2 extended synaptotagmin 2 located_in ISO (PMID:23791178) RGD PMID:23791178 NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
JBrowse link
G Esyt3 extended synaptotagmin 3 located_in ISO (PMID:23791178) RGD PMID:23791178 NCBI chr 8:99,870,418...99,917,298
Ensembl chr 8:99,871,149...99,917,232
JBrowse link
G Gramd1a GRAM domain containing 1A located_in ISO
ISS
(PMID:29469807)
GO_REF:0000024
RGD
UniProt
PMID:29469807 GO_REF:0000024 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
JBrowse link
G Gramd2a GRAM domain containing 2A located_in
is_active_in
ISO
IBA
(PMID:29469807)
PMID:21873635
RGD PMID:29469807 PMID:21873635 RGD:13792537 NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
JBrowse link
G Mospd2 motile sperm domain containing 2 located_in ISO (PMID:29858488) RGD PMID:29858488 NCBI chr  X:29,420,484...29,472,099
Ensembl chr  X:29,420,586...29,462,398
JBrowse link
G Osbpl1a oxysterol binding protein-like 1A located_in ISO
IEA
(PMID:29858488)
GO_REF:0000107
RGD
Ensembl
PMID:29858488 GO_REF:0000107 NCBI chr18:3,904,006...4,094,635
Ensembl chr18:3,904,006...4,094,585
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 located_in ISO (PMID:29858488) RGD PMID:29858488 NCBI chr 3:106,125,961...106,146,568
Ensembl chr 3:106,125,951...106,146,586
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 located_in ISO (PMID:24105263), (PMID:28377464), (PMID:29858488) RGD PMID:24105263 PMID:28377464 PMID:29858488 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976
JBrowse link
G Stard3nl STARD3 N-terminal like located_in ISO (PMID:24105263), (PMID:29858488) RGD PMID:24105263 PMID:29858488 NCBI chr17:45,583,278...45,617,226
Ensembl chr17:45,583,266...45,617,226
JBrowse link
endoplasmic reticulum-endosome membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mospd2 motile sperm domain containing 2 located_in ISO (PMID:29858488) RGD PMID:29858488 NCBI chr  X:29,420,484...29,472,099
Ensembl chr  X:29,420,586...29,462,398
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 located_in ISO (PMID:24105263) RGD PMID:24105263 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976
JBrowse link
G Stard3nl STARD3 N-terminal like located_in ISO (PMID:24105263) RGD PMID:24105263 NCBI chr17:45,583,278...45,617,226
Ensembl chr17:45,583,266...45,617,226
JBrowse link
G Tmcc1 transmembrane and coiled-coil domain family 1 located_in ISO (PMID:30220460) RGD PMID:30220460 NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620
JBrowse link
endoplasmic reticulum-plasma membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd2l C2CD2-like located_in ISO (PMID:28209843) RGD PMID:28209843 NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340
JBrowse link
G Esyt2 extended synaptotagmin 2 located_in ISO (PMID:27044890), (PMID:30220461) RGD PMID:27044890 PMID:30220461 NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
JBrowse link
G Esyt3 extended synaptotagmin 3 located_in ISO (PMID:30220461) RGD PMID:30220461 NCBI chr 8:99,870,418...99,917,298
Ensembl chr 8:99,871,149...99,917,232
JBrowse link
G Gramd1a GRAM domain containing 1A located_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6242147|PMID:30220461)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30220461 GO_REF:0000024 GO_REF:0000107 MGI:6242147 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
JBrowse link
G Gramd1b GRAM domain containing 1B located_in ISO (PMID:30220461)
(MGI:6242147|PMID:30220461)
RGD PMID:30220461 MGI:6242147 NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925
JBrowse link
G Gramd1c GRAM domain containing 1C located_in ISO (MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:6242147 NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570
JBrowse link
G Osbpl5 oxysterol binding protein-like 5 located_in ISO (PMID:26206935), (PMID:30220461) RGD PMID:26206935 PMID:30220461 NCBI chr 1:198,862,071...198,916,469
Ensembl chr 1:198,862,055...198,916,469
JBrowse link
G Sacm1l SAC1 like phosphatidylinositide phosphatase located_in ISO
IDA
(PMID:27044890) RGD PMID:27044890 PMID:27044890 RGD:25671387 NCBI chr 8:123,176,017...123,232,413
Ensembl chr 8:123,172,536...123,232,413
JBrowse link
G Saraf store-operated calcium entry-associated regulatory factor located_in ISO
ISS
(PMID:22464749)
GO_REF:0000024
RGD
UniProt
PMID:22464749 GO_REF:0000024 NCBI chr16:58,017,231...58,035,481
Ensembl chr16:58,017,231...58,035,545
JBrowse link
G Stimate STIM activating enhancer located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr16:6,013,392...6,070,829
Ensembl chr16:6,013,369...6,071,816
JBrowse link
mitochondria-associated endoplasmic reticulum membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 located_in ISO
ISS
(PMID:27995898)
GO_REF:0000024
RGD
UniProt
PMID:27995898 GO_REF:0000024 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
JBrowse link
G Atg14 autophagy related 14 located_in
is_active_in
ISO
IBA
(MGI:5476569|PMID:23455425)
PMID:21873635
RGD PMID:23455425 PMID:21873635 MGI:5476569, RGD:13792537 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg5 autophagy related 5 located_in IEA
ISO
GO_REF:0000107
(MGI:5476569|PMID:23455425)
Ensembl
RGD
PMID:23455425 GO_REF:0000107 MGI:5476569 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 located_in ISO (PMID:31206022) RGD PMID:31206022 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506
JBrowse link
G Bcl2l10 BCL2 like 10 located_in ISS
ISO
GO_REF:0000024
(PMID:27995898)
UniProt
RGD
PMID:27995898 GO_REF:0000024 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Canx calnexin located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Clcc1 chloride channel CLIC-like 1 located_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:31653868)
UniProt
Ensembl
RGD
PMID:31653868 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 located_in ISO (PMID:23510452) RGD PMID:23510452 NCBI chr 1:65,525,206...65,539,538 JBrowse link
G Mboat7l1 membrane bound O-acyltransferase domain containing 7-like 1 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:65,525,213...65,539,538 JBrowse link
G Pdzd8 PDZ domain containing 8 located_in
is_active_in
ISO
IBA
(PMID:29097544)
PMID:21873635
(MGI:6094720|PMID:29097544)
RGD PMID:29097544 PMID:21873635 MGI:6094720, RGD:13792537 NCBI chr 1:258,449,218...258,506,828
Ensembl chr 1:258,449,218...258,506,828
JBrowse link
G Rab32 RAB32, member RAS oncogene family located_in ISO (PMID:25767741) RGD PMID:25767741 NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
JBrowse link
G Rab38 RAB38, member RAS oncogene family located_in ISO (PMID:25767741) RGD PMID:25767741 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Serac1 serine active site containing 1 located_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727
JBrowse link
G Stx17 syntaxin 17 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr 5:62,446,138...62,506,108
Ensembl chr 5:62,446,187...62,504,451
JBrowse link
G Tmem41b transmembrane protein 41B located_in ISO
ISS
(PMID:30352685)
(MGI:6280160|PMID:30352685)
GO_REF:0000024
RGD
UniProt
PMID:30352685 GO_REF:0000024 MGI:6280160 NCBI chr 1:164,012,585...164,026,967
Ensembl chr 1:164,012,592...164,026,933
JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 located_in ISO (PMID:31735293) RGD PMID:31735293 NCBI chr 3:69,754,937...69,762,587
Ensembl chr 3:69,754,939...69,762,587
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 located_in IEA
ISO
GO_REF:0000107
(PMID:31206022)
Ensembl
RGD
PMID:31206022 GO_REF:0000107 NCBI chr 1:79,358,781...79,370,976
Ensembl chr 1:79,358,786...79,370,915
JBrowse link
G Zfyve1 zinc finger FYVE-type containing 1 located_in ISO (PMID:23455425) RGD PMID:23455425 NCBI chr 6:103,184,938...103,234,111
Ensembl chr 6:103,184,938...103,234,039
JBrowse link
mitochondrial crista junction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Micos13 mitochondrial contact site and cristae organizing system subunit 13 located_in ISO (PMID:25997101) RGD PMID:25997101 NCBI chr 9:1,439,058...1,442,092
Ensembl chr 9:1,439,058...1,442,076
JBrowse link
mitochondrial inner-outer membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ckmt1 creatine kinase, mitochondrial 1 IDA RGD PMID:1998693 RGD:11565110 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
JBrowse link
nucleus-vacuole junction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584
JBrowse link
vacuole-isolation membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg16l1 autophagy related 16-like 1 located_in ISO (PMID:28890335) RGD PMID:28890335 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link

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