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ONTOLOGY REPORT - ANNOTATIONS


Term:protein serine/threonine kinase activator activity
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Accession:GO:0043539 term browser browse the term
Definition:Binds to and increases the activity of a protein serine/threonine kinase.
Synonyms:exact_synonym: protein ser/thr kinase activator activity


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protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long chain family member 1 enables ISO (PMID:20667975) MGI PMID:20667975 NCBI chrNW_004624769:15,503,757...15,584,741
Ensembl chrNW_004624769:15,503,757...15,584,777
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 enables ISO (PMID:16049005) UniProt PMID:16049005 NCBI chrNW_004624899:74,080...170,565 JBrowse link
G Atg13 autophagy related 13 enables ISO (PMID:19225151) UniProt PMID:19225151 NCBI chrNW_004624767:1,924,672...1,953,868 JBrowse link
G Bmp2 bone morphogenetic protein 2 enables ISO (PMID:22227436)
(PMID:21976273), (PMID:7798324)
UniProt
MGI
PMID:7798324 PMID:21976273 PMID:22227436 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484
JBrowse link
G Bmp4 bone morphogenetic protein 4 enables ISO (PMID:14749725) UniProt PMID:14749725 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743
JBrowse link
G Bmp7 bone morphogenetic protein 7 enables ISO (PMID:31208997) UniProt PMID:31208997 NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742
JBrowse link
G Cab39 calcium binding protein 39 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624843:4,129,755...4,217,406
Ensembl chrNW_004624843:4,130,052...4,217,540
JBrowse link
G Cab39l calcium binding protein 39 like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624748:5,238,235...5,408,654
Ensembl chrNW_004624748:5,252,994...5,411,002
JBrowse link
G Calm1 calmodulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:12,030,264...12,041,682
Ensembl chrNW_004624734:12,030,001...12,041,772
JBrowse link
G Calm2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,525,290...28,541,562
Ensembl chrNW_004624738:28,525,285...28,541,514
JBrowse link
G Calm3 calmodulin 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:6,957,775...6,966,505
Ensembl chrNW_004624832:6,958,820...6,966,514
JBrowse link
G Ccdc88a coiled-coil domain containing 88A enables ISO (PMID:15753085) UniProt PMID:15753085 NCBI chrNW_004624833:6,117,260...6,260,211
Ensembl chrNW_004624833:6,116,686...6,260,211
JBrowse link
G Cd40lg CD40 ligand enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338
JBrowse link
G Cdk5r1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA
RGD
Ensembl
PMID:8662984 GO_REF:0000107 RGD:632374 NCBI chrNW_004624875:538,752...542,874
Ensembl chrNW_004624875:538,790...543,044
JBrowse link
G Dab2ip DAB2 interacting protein enables ISO (PMID:19903888) GO_Central PMID:19903888 NCBI chrNW_004624760:13,472,500...13,658,070
Ensembl chrNW_004624760:13,472,672...13,657,930
JBrowse link
G Dazap2 DAZ associated protein 2 enables ISO (PMID:18762249) WB PMID:18762249 NCBI chrNW_004624816:1,020,074...1,024,834
Ensembl chrNW_004624816:1,020,382...1,024,808
JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624809:5,471,056...5,494,188
Ensembl chrNW_004624809:5,471,230...5,493,974
JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked enables ISO (PMID:23413191) UniProt PMID:23413191 NCBI chrNW_004624762:14,290,267...14,305,437
Ensembl chrNW_004624762:14,290,267...14,305,633
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 enables ISO (PMID:32132706), (PMID:32132707), (PMID:37327776), (PMID:37550454), (PMID:37832546), (PMID:38340717) UniProt PMID:32132706 PMID:32132707 PMID:37327776 PMID:37550454 PMID:37832546 More... NCBI chrNW_004624774:1,135,680...1,154,628
Ensembl chrNW_004624774:1,136,731...1,150,625
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624762:5,916,038...5,923,783 JBrowse link
G Fam20a FAM20A golgi associated secretory pathway pseudokinase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624870:3,576,995...3,632,964
Ensembl chrNW_004624870:3,577,386...3,632,967
JBrowse link
G Fermt2 FERM domain containing kindlin 2 enables ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004624731:16,168,179...16,247,747
Ensembl chrNW_004624731:16,168,207...16,246,778
JBrowse link
G Gcn1 GCN1 activator of EIF2AK4 enables ISO (PMID:24333428)
(PMID:32324833)
UniProt PMID:24333428 PMID:32324833 NCBI chrNW_004624747:13,446,352...13,510,501
Ensembl chrNW_004624747:13,446,373...13,510,508
JBrowse link
G Igf1 insulin like growth factor 1 enables ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300
JBrowse link
G Igf2 insulin like growth factor 2 enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624767:14,969,977...14,997,577
Ensembl chrNW_004624767:14,969,866...14,979,026
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 enables ISO (PMID:17563371) BHF-UCL PMID:17563371 NCBI chrNW_004624768:17,703,113...17,797,922
Ensembl chrNW_004624768:17,702,728...17,799,022
JBrowse link
G Irgm immunity related GTPase M enables ISO (PMID:28389568)
(PMID:25891078)
UniProt PMID:25891078 PMID:28389568 NCBI chrNW_004624733:41,241,488...41,248,162 JBrowse link
G Lgals9 galectin 9 enables ISO (PMID:25065622) UniProt PMID:25065622 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Ltf lactotransferrin enables ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 enables ISO (PMID:8388392) UniProt PMID:8388392 NCBI chrNW_004624781:6,222,365...6,285,398
Ensembl chrNW_004624781:6,222,365...6,285,531
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 enables ISO (PMID:8388392) UniProt PMID:8388392 NCBI chrNW_004624828:5,489,085...5,511,166
Ensembl chrNW_004624828:5,488,814...5,511,445
JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 enables ISO (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chrNW_004624904:1,579,792...1,598,595
Ensembl chrNW_004624904:1,578,986...1,598,939
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 enables ISO (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chrNW_004624730:71,162,598...71,313,369
Ensembl chrNW_004624730:71,161,646...71,312,442
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624913:50,622...54,643
Ensembl chrNW_004624913:47,962...55,048
JBrowse link
G Mob1a MOB kinase activator 1A enables ISO (PMID:18328708) UniProt PMID:18328708 NCBI chrNW_004624749:29,284,516...29,308,057
Ensembl chrNW_004624749:29,284,185...29,308,515
JBrowse link
G Mob1b MOB kinase activator 1B enables ISO (PMID:18328708) UniProt PMID:18328708 NCBI chrNW_004624890:2,252,580...2,331,868 JBrowse link
G Mtcp1 mature T cell proliferation 1 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624963:212,524...218,187
Ensembl chrNW_004624963:215,462...218,187
JBrowse link
G Nbn nibrin enables ISO (PMID:16622404) UniProt PMID:16622404 NCBI chrNW_004624744:2,013,936...2,061,726
Ensembl chrNW_004624744:2,013,922...2,061,708
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO Akt (protein kinase B); Ser473, Thr308 RGD PMID:15023862 RGD:1642719 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453
JBrowse link
G Parp16 poly(ADP-ribose) polymerase family member 16 enables ISO (PMID:23103912) UniProt PMID:23103912 NCBI chrNW_004624781:7,216,058...7,258,839
Ensembl chrNW_004624781:7,221,296...7,259,272
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase enables ISO (PMID:16186805) UniProt PMID:16186805 NCBI chrNW_004624754:20,810,398...20,815,182
Ensembl chrNW_004624754:20,808,701...20,815,206
JBrowse link
G Rad50 RAD50 double strand break repair protein enables ISO (PMID:16622404) UniProt PMID:16622404 NCBI chrNW_004624733:39,445,083...39,544,415
Ensembl chrNW_004624733:39,447,461...39,544,409
JBrowse link
G Rheb Ras homolog, mTORC1 binding enables ISO (PMID:15854902), (PMID:29236692) UniProt PMID:15854902 PMID:29236692 NCBI chrNW_004624800:5,221,630...5,262,980
Ensembl chrNW_004624800:5,221,605...5,264,965
JBrowse link
G Rictor RPTOR independent companion of MTOR complex 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624759:15,837,027...15,973,248
Ensembl chrNW_004624759:15,837,064...15,968,894
JBrowse link
G Sav1 salvador family WW domain containing protein 1 enables ISO (PMID:29063833), (PMID:35429439) UniProt PMID:29063833 PMID:35429439 NCBI chrNW_004624731:18,262,110...18,282,386 JBrowse link
G Slc27a1 solute carrier family 27 member 1 enables ISO (PMID:19560442)
(PMID:20667975)
MGI PMID:19560442 PMID:20667975 NCBI chrNW_004624908:531,313...549,570
Ensembl chrNW_004624908:531,308...549,990
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624751:20,091,612...20,096,581
Ensembl chrNW_004624751:20,091,609...20,096,563
JBrowse link
G Strada STE20 related adaptor alpha enables IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624849:1,192,714...1,231,001
Ensembl chrNW_004624849:1,192,606...1,231,224
JBrowse link
G Stradb STE20 related adaptor beta enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624899:255,042...275,258
Ensembl chrNW_004624899:255,042...275,235
JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 enables ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004624752:8,912,467...8,937,313
Ensembl chrNW_004624752:8,913,900...8,937,329
JBrowse link
G Taok1 TAO kinase 1 enables ISO PMID:14517247 ARUK-UCL PMID:14517247 RGD:8553906 NCBI chrNW_004624786:1,920,037...2,054,795
Ensembl chrNW_004624786:1,968,991...2,045,948
JBrowse link
G Tcl1a TCL1 family AKT coactivator A enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624734:8,111,655...8,116,084 JBrowse link
G Tgfb1 transforming growth factor beta 1 enables ISO (PMID:25065622)
(PMID:32644293)
UniProt PMID:25065622 PMID:32644293 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 enables ISO (PMID:21777809) UniProt PMID:21777809 NCBI chrNW_004624730:9,916,717...9,994,666
Ensembl chrNW_004624730:9,914,140...9,994,775
JBrowse link
cyclin-dependent protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 enables ISO (PMID:19237565) UniProt PMID:19237565 NCBI chrNW_004624767:17,470,310...17,483,082
Ensembl chrNW_004624767:17,469,622...17,483,191
JBrowse link
G Ccnd2 cyclin D2 enables ISO (PMID:18827403) UniProt PMID:18827403 NCBI chrNW_004624860:1,383,015...1,405,107
Ensembl chrNW_004624860:1,382,948...1,405,107
JBrowse link
G Ccnd3 cyclin D3 enables ISO (PMID:8114739) UniProt PMID:8114739 NCBI chrNW_004624754:17,148,108...17,194,626
Ensembl chrNW_004624754:17,148,076...17,194,000
JBrowse link
G Ccnt1 cyclin T1 enables ISO (PMID:29849146), (PMID:35393539) UniProt PMID:29849146 PMID:35393539 NCBI chrNW_004624816:3,396,740...3,445,976
Ensembl chrNW_004624816:3,421,709...3,442,170
JBrowse link
G Cdk5r1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA
RGD
TreeGrafter
Ensembl
InterPro
PMID:8662984 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:632374 NCBI chrNW_004624875:538,752...542,874
Ensembl chrNW_004624875:538,790...543,044
JBrowse link
G Cdk5r2 cyclin dependent kinase 5 regulatory subunit 2 enables ISO (PMID:11517264)
(PMID:10683146)
MGI
ARUK-UCL
PMID:10683146 PMID:11517264 NCBI chrNW_004624823:6,053,469...6,054,748
Ensembl chrNW_004624823:6,053,550...6,054,659
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase enables IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004624734:40,148,761...40,389,233
Ensembl chrNW_004624734:40,154,577...40,389,402
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 16462
    molecular function regulator activity 1773
      enzyme regulator activity 1104
        enzyme activator activity 502
          kinase activator activity 131
            protein kinase activator activity 121
              protein serine/threonine kinase activator activity 61
                cyclin-dependent protein serine/threonine kinase activator activity 7
                eukaryotic elongation factor-2 kinase activator activity 0
paths to the root