Mob1b (MOB kinase activator 1B) - Rat Genome Database

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Gene: Mob1b (MOB kinase activator 1B) Heterocephalus glaber
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Symbol: Mob1b
Name: MOB kinase activator 1B
RGD ID: 18931436
Description: ENCODES a protein that exhibits kinase activator activity (ortholog); kinase binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN hippo signaling (ortholog); regulation of protein autophosphorylation (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248902,252,580 - 2,331,868 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mob1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248902,252,580 - 2,331,868 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MOB1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38470,901,851 - 70,988,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl470,902,326 - 71,022,449 (+)EnsemblGRCh38hg38GRCh38
GRCh37471,768,086 - 71,853,885 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36471,986,928 - 72,072,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 34472,133,098 - 72,218,926NCBI
Celera469,125,042 - 69,210,916 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef467,573,701 - 67,659,043 (+)NCBIHuRef
CHM1_1471,803,992 - 71,889,766 (+)NCBICHM1_1
T2T-CHM13v2.0474,244,289 - 74,330,605 (+)NCBIT2T-CHM13v2.0
Mob1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39588,868,730 - 88,906,314 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl588,868,714 - 88,912,079 (+)EnsemblGRCm39 Ensembl
GRCm38588,720,871 - 88,758,455 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl588,720,855 - 88,764,220 (+)EnsemblGRCm38mm10GRCm38
MGSCv37589,149,896 - 89,187,480 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36589,795,458 - 89,832,550 (+)NCBIMGSCv36mm8
Celera586,870,214 - 86,907,770 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.92NCBI
Mob1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,617,136 - 19,649,919 (-)NCBIGRCr8
mRatBN7.21419,333,058 - 19,365,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,332,459 - 19,365,845 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1419,322,781 - 19,355,522 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01420,641,644 - 20,674,385 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01419,344,018 - 19,376,773 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01420,960,052 - 20,992,753 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1420,960,052 - 20,992,753 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01420,870,121 - 20,903,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41420,911,418 - 20,944,224 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11420,918,734 - 20,944,103 (-)NCBI
Celera1418,672,400 - 18,705,217 (-)NCBICelera
Cytogenetic Map14p22NCBI
Mob1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554472,077,768 - 2,092,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554472,077,768 - 2,141,373 (-)NCBIChiLan1.0ChiLan1.0
MOB1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2359,096,686 - 59,182,249 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1459,291,722 - 59,377,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0453,236,077 - 53,321,548 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1459,579,790 - 59,664,711 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl459,585,888 - 59,664,711 (-)Ensemblpanpan1.1panPan2
MOB1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11360,145,168 - 60,197,916 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1360,145,366 - 60,195,463 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1359,879,300 - 59,935,300 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01360,950,317 - 61,006,877 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1360,950,396 - 61,006,872 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11360,565,698 - 60,622,147 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01360,057,229 - 60,113,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01361,204,611 - 61,261,088 (+)NCBIUU_Cfam_GSD_1.0
Mob1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528515,394,707 - 15,463,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365983,849,415 - 3,915,758 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365983,846,735 - 3,915,747 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOB1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl867,648,042 - 67,702,227 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1867,647,862 - 67,702,235 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2871,555,822 - 71,606,605 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MOB1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1719,418,464 - 19,493,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl719,418,548 - 19,491,465 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660843,364,295 - 3,448,099 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004871742   ⟹   XP_004871799
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248902,252,580 - 2,331,868 (+)NCBI
RefSeq Acc Id: XM_021249806   ⟹   XP_021105465
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248902,283,758 - 2,331,868 (+)NCBI
RefSeq Acc Id: XM_021249807   ⟹   XP_021105466
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248902,283,722 - 2,331,868 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004871799 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105465 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105466 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000000955
RefSeq Acc Id: XP_004871799   ⟸   XM_004871742
- Peptide Label: isoform X1
- UniProtKB: G5BN03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021105466   ⟸   XM_021249807
- Peptide Label: isoform X3
- UniProtKB: G5BN03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021105465   ⟸   XM_021249806
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000771 ENTREZGENE
Ensembl Transcript ENSHGLT00000000996 ENTREZGENE
Gene3D-CATH MOB kinase activator UniProtKB/TrEMBL
InterPro MOB_kinase_act_fam UniProtKB/TrEMBL
  MOB_kinase_act_sf UniProtKB/TrEMBL
NCBI Gene Mob1b ENTREZGENE
PANTHER MOB KINASE ACTIVATOR 1B UniProtKB/TrEMBL
  MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB UniProtKB/TrEMBL
Pfam Mob1_phocein UniProtKB/TrEMBL
SMART Mob1_phocein UniProtKB/TrEMBL
Superfamily-SCOP Mob1/phocein UniProtKB/TrEMBL
UniProt A0AAX6QF37_HETGA UniProtKB/TrEMBL
  A0AAX6S866_HETGA UniProtKB/TrEMBL
  A0AAX6S8H0_HETGA UniProtKB/TrEMBL
  G5BN03 ENTREZGENE, UniProtKB/TrEMBL