Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:NADPH oxidase complex
go back to main search page
Accession:GO:0043020 term browser browse the term
Definition:A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
Synonyms:narrow_synonym: flavocytochrome b558
 related_synonym: respiratory-burst oxidase


show annotations for term's descendants           Sort by:
NADPH oxidase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain part_of
located_in		 IDA
IMP
ISO
IEA
IBA		 PMID:8798532
(PMID:1763037), (PMID:3305576)
GO_REF:0000104
(PMID:22423966)
GO_REF:0000033
(PMID:24739962)		 RGD
UniProt
GO_Central		 PMID:1763037 PMID:3305576 PMID:22423966 PMID:24739962 PMID:15322091 More... GO_REF:0000033 GO_REF:0000104, RGD:1580287, RGD:2291907, RGD:2317869 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain part_of IDA
IBA
ISO		 GO_REF:0000033
(PMID:24739962)
(PMID:15338276), (PMID:3305576)		 GO_Central
RGD		 PMID:3305576 PMID:15338276 PMID:24739962 PMID:15322091 PMID:12241540 GO_REF:0000033, RGD:1580287, RGD:2291907 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Duox1 dual oxidase 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 part_of IDA
ISO
IBA		 (PMID:2550933), (PMID:8280052)
GO_REF:0000033		 RGD
GO_Central		 PMID:2550933 PMID:8280052 PMID:12241540 GO_REF:0000033, RGD:2291907 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 part_of ISO
IEA		 (PMID:8280052)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:8280052 GO_REF:0000002 GO_REF:0000107 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 part_of ISO
IBA		 (PMID:8280052)
GO_REF:0000033		 RGD
GO_Central		 PMID:8280052 GO_REF:0000033 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Nox1 NADPH oxidase 1 part_of IDA
IEA
ISO
IBA		 GO_REF:0000107
(PMID:16636067)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:16636067 PMID:15322091 GO_REF:0000033 GO_REF:0000107, RGD:1580287 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox3 NADPH oxidase 3 part_of IBA
ISO		 GO_REF:0000033
(PMID:17140397)		 GO_Central
RGD		 PMID:17140397 GO_REF:0000033 NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851 		JBrowse link
G Nox4 NADPH oxidase 4 part_of IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:15322091 GO_REF:0000033, RGD:1580287 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Noxa1 NADPH oxidase activator 1 part_of ISO (PMID:16636067) RGD PMID:16636067 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 part_of ISO (PMID:16636067) RGD PMID:16636067 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20827
    protein-containing complex 6555
      membrane protein complex 1410
        plasma membrane protein complex 670
          NADPH oxidase complex 12
Path 2
Term Annotations click to browse term
  cellular_component 20827
    cellular anatomical structure 20627
      membrane 10365
        plasma membrane 6488
          plasma membrane protein complex 670
            NADPH oxidase complex 12
paths to the root