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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter;   negative regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041

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negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10318824), (PMID:19204372) Ensembl
MGI		 PMID:10318824 PMID:19204372 GO_REF:0000107 NCBI chrNW_004624913:1,139,165...1,195,477
Ensembl chrNW_004624913:1,139,165...1,195,230 		JBrowse link
G Eapp E2F associated phosphoprotein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15716352) MGI
Ensembl		 PMID:15716352 GO_REF:0000107 NCBI chrNW_004624838:2,159,869...2,180,879
Ensembl chrNW_004624838:2,160,036...2,180,597 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chrNW_004624800:6,781,848...6,874,221
Ensembl chrNW_004624800:6,802,901...6,874,196 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:14580347) HGNC-UCL PMID:14580347 NCBI chrNW_004624795:257,553...260,685 JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chrNW_004624771:14,756,088...14,766,106
Ensembl chrNW_004624771:14,756,100...14,765,832 		JBrowse link
G Nelfa negative elongation factor complex member A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21670248) MGI
TreeGrafter		 PMID:21670248 GO_REF:0000118 NCBI chrNW_004624755:25,498,336...25,508,753
Ensembl chrNW_004624755:25,498,431...25,508,753 		JBrowse link
G Nelfb negative elongation factor complex member B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624760:692,735...703,571
Ensembl chrNW_004624760:692,735...705,328 		JBrowse link
G Nelfcd negative elongation factor complex member C/D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:25,267,334...25,280,844
Ensembl chrNW_004624741:25,267,359...25,280,844 		JBrowse link
G Nelfe negative elongation factor complex member E acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21670248) MGI
TreeGrafter		 PMID:21670248 GO_REF:0000118 NCBI chrNW_004624754:24,300,012...24,310,777
Ensembl chrNW_004624754:24,300,602...24,310,671 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35393539) UniProt PMID:35393539 NCBI chrNW_004624807:446,662...478,571
Ensembl chrNW_004624807:446,647...479,069 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:5,530,411...5,568,355
Ensembl chrNW_004624801:5,530,992...5,567,628 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:20550933) UniProt PMID:20550933 NCBI chrNW_004624730:61,592,967...61,627,585
Ensembl chrNW_004624730:61,591,943...61,627,170 		JBrowse link
G Rnf8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:20,683,133...20,714,469
Ensembl chrNW_004624754:20,679,867...20,714,522 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:17284610) MGI PMID:17284610 NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:25247314), (PMID:31399344) UniProt PMID:25247314 PMID:31399344 NCBI chrNW_004624828:5,441,973...5,449,549
Ensembl chrNW_004624828:5,442,057...5,451,520 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) MGI PMID:21670248 NCBI chrNW_004624871:183,495...189,838
Ensembl chrNW_004624871:184,298...189,798 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004624731:5,350,912...5,359,286 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17637
    cellular process 17219
      metabolic process 11013
        biosynthetic process 7918
          macromolecule biosynthetic process 7028
            gene expression 6599
              DNA-templated transcription 3230
                DNA-templated transcription elongation 93
                  transcription elongation by RNA polymerase II 78
                    negative regulation of transcription elongation by RNA polymerase II 17
Path 2
Term Annotations click to browse term
  biological_process 17637
    cellular process 17219
      metabolic process 11013
        primary metabolic process 9856
          nucleobase-containing compound metabolic process 5893
            nucleic acid metabolic process 5391
              RNA metabolic process 4853
                RNA biosynthetic process 4656
                  DNA-templated transcription 3230
                    DNA-templated transcription elongation 93
                      regulation of DNA-templated transcription elongation 55
                        negative regulation of DNA-templated transcription, elongation 20
                          negative regulation of transcription elongation by RNA polymerase II 17
paths to the root