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ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor 5 signaling pathway
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Accession:GO:0034146 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
Synonyms:exact_synonym: TLR5 signaling pathway;   toll-like receptor 5 signalling pathway


show annotations for term's descendants           Sort by:
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:16751103) RGD PMID:16751103 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) RGD PMID:12447442 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO (PMID:14625549), (PMID:17128265) RGD PMID:14625549 PMID:17128265 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:19912257) RGD PMID:19912257 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3002
      activation of immune response 576
        immune response-activating signaling pathway 494
          immune response-activating cell surface receptor signaling pathway 302
            innate immune response activating cell surface receptor signaling pathway 90
              cell surface pattern recognition receptor signaling pathway 78
                cell surface toll-like receptor signaling pathway 72
                  toll-like receptor 5 signaling pathway 4
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    positive regulation of toll-like receptor 5 signaling pathway 0
                    regulation of toll-like receptor 5 signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 20069
    response to stimulus 10792
      response to external stimulus 2751
        response to external biotic stimulus 1863
          response to other organism 1859
            defense response to other organism 1311
              defense response to symbiont 1177
                innate immune response 1005
                  regulation of innate immune response 480
                    positive regulation of innate immune response 386
                      activation of innate immune response 314
                        innate immune response-activating signaling pathway 287
                          innate immune response activating cell surface receptor signaling pathway 90
                            cell surface pattern recognition receptor signaling pathway 78
                              cell surface toll-like receptor signaling pathway 72
                                toll-like receptor 5 signaling pathway 4
                                  negative regulation of toll-like receptor 5 signaling pathway 1
                                  positive regulation of toll-like receptor 5 signaling pathway 0
                                  regulation of toll-like receptor 5 signaling pathway + 1
paths to the root