Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor 5 signaling pathway
go back to main search page
Accession:GO:0034146 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
Synonyms:exact_synonym: TLR5 signaling pathway;   toll-like receptor 5 signalling pathway


show annotations for term's descendants           Sort by:
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) RGD PMID:12447442 MGI:3531416 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4943853|PMID:19912257) RGD PMID:19912257 MGI:4943853 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      activation of immune response 572
        immune response-activating signaling pathway 485
          immune response-activating cell surface receptor signaling pathway 304
            innate immune response activating cell surface receptor signaling pathway 90
              cell surface pattern recognition receptor signaling pathway 77
                cell surface toll-like receptor signaling pathway 72
                  toll-like receptor 5 signaling pathway 3
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    positive regulation of toll-like receptor 5 signaling pathway 0
                    regulation of toll-like receptor 5 signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      response to external stimulus 2746
        response to external biotic stimulus 1854
          response to other organism 1850
            defense response to other organism 1305
              defense response to symbiont 1169
                innate immune response 996
                  regulation of innate immune response 458
                    positive regulation of innate immune response 375
                      activation of innate immune response 304
                        innate immune response-activating signaling pathway 278
                          innate immune response activating cell surface receptor signaling pathway 90
                            cell surface pattern recognition receptor signaling pathway 77
                              cell surface toll-like receptor signaling pathway 72
                                toll-like receptor 5 signaling pathway 3
                                  negative regulation of toll-like receptor 5 signaling pathway 1
                                  positive regulation of toll-like receptor 5 signaling pathway 0
                                  regulation of toll-like receptor 5 signaling pathway + 1
paths to the root