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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of interleukin-4 production
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Accession:GO:0032753 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
Synonyms:exact_synonym: positive regulation of IL-4 production;   up regulation of interleukin-4 production;   upregulation of interleukin-4 production
 narrow_synonym: activation of interleukin-4 production;   positive regulation of interleukin-4 biosynthetic process;   positive regulation of interleukin-4 secretion;   stimulation of interleukin-4 production
 alt_id: GO:0045404;   GO:0150135


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positive regulation of interleukin-4 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426)
(PMID:11754812), (PMID:7538697)
(PMID:10201995)		 MGI PMID:7538697 PMID:9133426 PMID:10201995 PMID:11754812 NCBI chr38:23,489,169...23,491,712 JBrowse link
G CD28 CD28 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:11894097) MGI PMID:11894097 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD40LG CD40 ligand involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656 		JBrowse link
G DLA-12 MHC class I DLA-12 involved_in ISO (PMID:25631937) UniProt PMID:25631937 NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561 		JBrowse link
G EPX eosinophil peroxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16926417) Ensembl
MGI		 PMID:16926417 GO_REF:0000107 NCBI chr 9:32,855,568...32,865,445
Ensembl chr 9:32,855,507...32,865,022 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in ISO (MGI:3831068|PMID:19098920) UniProt PMID:19098920 MGI:3831068 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20944002) Ensembl
MGI		 PMID:20944002 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10549629)
(PMID:17658278)		 Ensembl
MGI		 PMID:10549629 PMID:17658278 GO_REF:0000107 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in ISO (MGI:1929009|PMID:11343123) UniProt PMID:11343123 MGI:1929009 NCBI chr31:38,084,861...38,094,743 JBrowse link
G IL1RAP interleukin 1 receptor accessory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:22,547,422...22,628,628
Ensembl chr34:22,546,899...22,623,544 		JBrowse link
G IL20RB interleukin 20 receptor subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19124723) Ensembl
MGI		 PMID:19124723 GO_REF:0000107 NCBI chr23:33,384,057...33,421,619
Ensembl chr23:33,384,486...33,420,016 		JBrowse link
G IL33 interleukin 33 involved_in ISO (MGI:3775141|PMID:18268038) BHF-UCL PMID:18268038 MGI:3775141 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:25578313)
(PMID:20209097)		 UniProt PMID:20209097 PMID:25578313 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LOC102156778 bone marrow proteoglycan-like acts_upstream_of_or_within ISO (PMID:16926417) MGI PMID:16926417 NCBI chr18:38,753,269...38,760,730 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:100,989,605...101,003,162
Ensembl chr  X:100,989,685...101,001,885 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24038088) ARUK-UCL
Ensembl		 PMID:24038088 GO_REF:0000107 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:7,586,212...7,594,610
Ensembl chr 6:7,585,970...7,594,610 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17307
    multicellular organismal process 7952
      cytokine production 892
        positive regulation of cytokine production 543
          positive regulation of interleukin-4 production 27
Path 2
Term Annotations click to browse term
  biological_process 17307
    biological regulation 12007
      regulation of biological process 11676
        regulation of metabolic process 6173
          regulation of biosynthetic process 5066
            regulation of cellular biosynthetic process 4981
              regulation of macromolecule biosynthetic process 4885
                regulation of gene expression 4770
                  regulation of cytokine production 884
                    positive regulation of cytokine production 543
                      positive regulation of interleukin-4 production 27
paths to the root