Advanced Search (OLGA)

Gene: CD28 (CD28 molecule) Canis lupus familiaris

Analyze

Symbol:

CD28

Name:

CD28 molecule

RGD ID:

12199053

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); CD4-positive, alpha-beta T cell proliferation (ortholog); negative thymic T cell selection (ortholog); ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); asthma (ortholog); autoimmune disease (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); immunological synapse (inferred)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CD28 antigen (Tp44); cell surface protein; costimulatory molecule B7 receptor CD28; T-cell costimulatory molecule CD28; T-cell-specific surface glycoprotein CD28

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CD28 (CD28 molecule)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Cd28 (CD28 antigen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cd28 (Cd28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cd28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CD28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cd28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CD28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CD28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cd28 (CD28 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	12,503,849 - 12,536,362 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	12,503,811 - 12,532,854 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	13,387,259 - 13,416,196 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	12,440,597 - 12,473,128 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	12,440,613 - 12,471,203 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	12,397,782 - 12,426,685 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	12,360,914 - 12,389,827 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	12,361,906 - 12,391,080 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adult T-cell leukemia/lymphoma (ISO)

asthma (ISO)

autoimmune disease (ISO)

autoimmune lymphoproliferative syndrome type 2B (ISO)

Autoimmune Lymphoproliferative Syndrome, Type V (ISO)

berylliosis (ISO)

Chloracne (ISO)

chronic fatigue syndrome (ISO)

chronic obstructive pulmonary disease (ISO)

common variable immunodeficiency 1 (ISO)

diabetic angiopathy (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Autoimmune Myocarditis (ISO)

Experimental Autoimmune Neuritis (ISO)

Experimental Diabetes Mellitus (ISO)

human immunodeficiency virus infectious disease (ISO)

Human Influenza (ISO)

IMMUNODEFICIENCY 123 WITH HPV-RELATED VERRUCOSIS (ISO)

interstitial lung disease (ISO)

leukemia (ISO)

lymphopenia (ISO)

multiple sclerosis (ISO)

Neurodevelopmental Disorders (ISO)

paracoccidioidomycosis (ISO)

peripheral T-cell lymphoma (ISO)

primary cutaneous T-cell non-Hodgkin lymphoma (ISO)

primary pulmonary hypertension (ISO)

Pulmonary Arterial Hypertension (ISO)

pulmonary fibrosis (ISO)

pulmonary hypertension (ISO)

respiratory syncytial virus infectious disease (ISO)

rheumatoid arthritis (ISO)

rhinitis (ISO)

Sepsis (ISO)

type 1 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic signaling pathway (IEA,ISO)

CD4-positive, alpha-beta T cell proliferation (IEA,ISO)

immune response (IEA)

negative regulation of gene expression (IEA)

negative thymic T cell selection (IEA,ISO)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of CD4-positive, alpha-beta T cell proliferation (IEA,ISO)

positive regulation of gene expression (IEA)

positive regulation of inflammatory response to antigenic stimulus (IEA,ISO)

positive regulation of interleukin-10 production (IEA)

positive regulation of interleukin-2 production (IEA,ISO,ISS)

positive regulation of interleukin-4 production (IEA)

positive regulation of isotype switching to IgG isotypes (IEA,ISO)

positive regulation of mitotic nuclear division (IEA,ISS)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of T cell proliferation (IEA,ISO,ISS)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of regulatory T cell differentiation (IEA,ISO)

regulation of T cell proliferation (IEA)

regulatory T cell differentiation (IEA)

T cell activation (IEA)

T cell costimulation (IEA,ISO)

T cell proliferation (IEA,ISO)

T cell receptor signaling pathway (IEA,ISO)

transcription by RNA polymerase II (IEA,ISO)

Cellular Component

cell surface (IEA)

external side of plasma membrane (IEA)

immunological synapse (IEA)

membrane (IEA)

plasma membrane (IEA)

protein complex involved in cell adhesion (IEA)

Molecular Function

identical protein binding (ISO)

protein binding (ISO)

protein kinase binding (IEA)

References

Additional References at PubMed

PMID:8168859	PMID:11292534	PMID:21343872	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CD28
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	12,503,849 - 12,536,362 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	12,503,811 - 12,532,854 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	13,387,259 - 13,416,196 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	12,440,597 - 12,473,128 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	12,440,613 - 12,471,203 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	12,397,782 - 12,426,685 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	12,360,914 - 12,389,827 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	12,361,906 - 12,391,080 (+)	NCBI		UU_Cfam_GSD_1.0

CD28
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	203,706,482 - 203,738,912 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	203,706,517 - 203,739,756 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	204,571,205 - 204,603,635 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	204,279,443 - 204,310,801 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	204,396,703 - 204,428,062	NCBI
Celera	2	198,326,049 - 198,357,410 (+)	NCBI		Celera
Cytogenetic Map	2	q33.2	NCBI
HuRef	2	196,418,462 - 196,450,899 (+)	NCBI		HuRef
CHM1_1	2	204,577,787 - 204,610,219 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	204,188,401 - 204,220,837 (+)	NCBI		T2T-CHM13v2.0

Cd28
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	60,785,547 - 60,812,521 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	60,755,959 - 60,812,518 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	60,746,388 - 60,773,359 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	60,716,800 - 60,773,359 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	60,803,232 - 60,830,203 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	60,691,012 - 60,717,905 (+)	NCBI		MGSCv36	mm8
Celera	1	61,261,669 - 61,288,639 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	30.52	NCBI

Cd28
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	69,660,316 - 69,689,192 (+)	NCBI		GRCr8
mRatBN7.2	9	62,166,324 - 62,194,674 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	62,166,192 - 62,194,685 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	70,668,268 - 70,693,746 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	75,783,858 - 75,809,336 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	74,102,440 - 74,127,918 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	67,546,408 - 67,573,858 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	67,546,408 - 67,571,871 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	67,358,994 - 67,386,424 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	59,342,273 - 59,367,743 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	59,489,254 - 59,514,725 (+)	NCBI
Celera	9	59,589,124 - 59,614,592 (+)	NCBI		Celera
RH 3.4 Map	9	504.6	RGD
Cytogenetic Map	9	q32	NCBI

Cd28
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	11,162,282 - 11,192,991 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955457	11,159,769 - 11,253,099 (-)	NCBI	ChiLan1.0	ChiLan1.0

CD28
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	106,310,207 - 106,343,899 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	106,325,199 - 106,358,891 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	90,938,795 - 90,971,438 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	209,076,388 - 209,111,213 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	209,076,388 - 209,111,213 (+)	Ensembl	panpan1.1		panPan2

Cd28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	160,682,644 - 160,728,827 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936631	335,411 - 363,407 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936631	335,411 - 363,407 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CD28
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	107,128,203 - 107,162,935 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	107,128,103 - 107,155,431 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	118,472,553 - 118,502,433 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD28
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	89,471,710 - 89,505,152 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	89,471,730 - 89,500,387 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	109,879,825 - 109,913,281 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cd28
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624765	12,650,092 - 12,667,168 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CD28
326 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002623344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005308022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF154842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF259962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L22178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000020425 ⟹ ENSCAFP00000018952

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	37	12,503,905 - 12,532,854 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000046704 ⟹ ENSCAFP00000042021

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	37	12,503,811 - 12,532,854 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000063094 ⟹ ENSCAFP00000052654

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	37	12,509,011 - 12,532,854 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000071872 ⟹ ENSCAFP00000059474

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	37	12,503,981 - 12,532,854 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000084083 ⟹ ENSCAFP00000066244

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	37	12,507,539 - 12,532,854 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845032073 ⟹ ENSCAFP00845025079

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	37	12,440,613 - 12,471,203 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845032124 ⟹ ENSCAFP00845025115

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	37	12,440,633 - 12,471,203 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845032172 ⟹ ENSCAFP00845025152

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	37	12,440,714 - 12,471,203 (+)	Ensembl

RefSeq Acc Id:

NM_001003087 ⟹ NP_001003087

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	37	12,503,905 - 12,532,854 (+)	NCBI
Dog10K_Boxer_Tasha	37	13,387,259 - 13,416,196 (+)	NCBI
ROS_Cfam_1.0	37	12,440,638 - 12,469,618 (+)	NCBI
UMICH_Zoey_3.1	37	12,397,782 - 12,426,685 (+)	NCBI
UNSW_CanFamBas_1.0	37	12,360,914 - 12,389,827 (+)	NCBI
UU_Cfam_GSD_1.0	37	12,361,906 - 12,391,080 (+)	NCBI

Sequence:

show sequence

CATCCTCAGCTCCCCTCACACTTTGGGCTCCTCAGGGAGGAGGGGGCTGGAGCCCTGGACCACC
GTTAGCACAATGATCCTCAGGCTGCTTCTGGCCCTCAACTTCTTCCCCTCGATTCAAGTAACAG
AAAACAAGATTTTGGTGAAGCAGTTGCCCAGGCTTGTGGTATACAACAATGAGGTCAATCTGAG
CTGCAAGTATACCTACAACCTCTTCTCAAAGGAGTTCCGGGCATCCCTTTATAAGGGAGTAGAT
AGTGCTGTGGAAGTCTGTGTTGTGAATGGAAATTACTCCCATCAGCCTCAGTTCTACTCAAGTA
CAGGATTCGACTGTGATGGAAAACTGGGCAATGAAACAGTGACATTCTACCTCCGGAATTTGTT
CGTTAACCAAACGGATATTTACTTTTGCAAAATTGAGGTCATGTATCCACCTCCTTACATTGGC
AATGAGAAGAGCAATGGGACCATTATCCATGTGAAAGAAAAACATCTTTGTCCAGATGAGCTGT
TTCCTGATTCTTCTAAGCCATTTTGGGCACTGGTGGTGGTTGGTGCAGTCCTAGTTTTCTATAG
CTTGCTAGTAACAGTGGCTCTTTGTGCCTACTGGATAAAGAGTAAGAGTAGCAGGATCCTTCAG
AGTGACTACATGAACATGACCCCCCGGAGGCCGGGGCCCACCCGAAGGCACTACCAACCCTATG
CCCCAGCACGCGACTTTGCAGCATACCGCTCCTGACATGGACGCCTATCCAGATGCGAGCCGGC
TGGCAGCTCTTCACCTGCTCAACACAACTGCTCTGGATAGGAAAAACCCGCCTCGTCTTCAGCC
GGCCATGGGCTCCTTTTAGGGGCTCTTATTAGGCCACCGATGCCAATTTTTCTTGAATGACTAT
ACCAAATAACATTATTTTGAGACTCTGAAATGAAGTTAAAGAATATTACTGTGGCAGGCTCTAT
CTTGCAGTGCCATGACCCAAATTCCAACTTACCATGTATTTATTGACTTGAGGTTACAGTAGAA
AACAAAACAAAAAAAGCAATGGATTCTATTA

hide sequence

RefSeq Acc Id:

XR_005308022

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	37	12,440,597 - 12,473,128 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001003087	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA51453	(Get FASTA)	NCBI Sequence Viewer
	AAF72533	(Get FASTA)	NCBI Sequence Viewer
	AAG43370	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000018952.3
	ENSCAFP00000052654.1
	ENSCAFP00000066863.1
	ENSCAFP00030036095.1
	ENSCAFP00030036124.1
	ENSCAFP00030036156.1
	ENSCAFP00040041379.1
	ENSCAFP00040041383.1
	ENSCAFP00040041391.1
	ENSCAFP00040041397.1
	ENSCAFP00845025079
	ENSCAFP00845025079.1
	ENSCAFP00845025115.1
	ENSCAFP00845025152.1

RefSeq Acc Id:	NP_001003087 ⟸ NM_001003087
- Peptide Label:	precursor
- UniProtKB:	Q9GKP3 (UniProtKB/TrEMBL), A0A8C0TU71 (UniProtKB/TrEMBL), Q9N0N8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MILRLLLALNFFPSIQVTENKILVKQLPRLVVYNNEVNLSCKYTYNLFSKEFRASLYKGVDSAV EVCVVNGNYSHQPQFYSSTGFDCDGKLGNETVTFYLRNLFVNQTDIYFCKIEVMYPPPYIGNEK SNGTIIHVKEKHLCPDELFPDSSKPFWALVVVGAVLVFYSLLVTVALCAYWIKSKSSRILQSDY MNMTPRRPGPTRRHYQPYAPARDFAAYRS hide sequence

Ensembl Acc Id:

ENSCAFP00000066244 ⟸ ENSCAFT00000084083

Ensembl Acc Id:

ENSCAFP00000052654 ⟸ ENSCAFT00000063094

Ensembl Acc Id:

ENSCAFP00000018952 ⟸ ENSCAFT00000020425

Ensembl Acc Id:

ENSCAFP00000059474 ⟸ ENSCAFT00000071872

Ensembl Acc Id:

ENSCAFP00000042021 ⟸ ENSCAFT00000046704

Ensembl Acc Id:

ENSCAFP00845025115 ⟸ ENSCAFT00845032124

Ensembl Acc Id:

ENSCAFP00845025079 ⟸ ENSCAFT00845032073

Ensembl Acc Id:

ENSCAFP00845025152 ⟸ ENSCAFT00845032172

Protein Domains

Immunoglobulin V-set

Promoters

RGD ID:

13689124

Promoter ID:

EPDNEW_C7194

Type:

single initiation site

Name:

CD28_1

Description:

CD28 molecule

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	37	12,503,883 - 12,503,943	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000012872	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030022504	UniProtKB/TrEMBL
	ENSCAFG00040025394	UniProtKB/TrEMBL
	ENSCAFG00845018097	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020425.4	UniProtKB/TrEMBL
	ENSCAFT00000063094.2	UniProtKB/TrEMBL
	ENSCAFT00000106862.1	UniProtKB/TrEMBL
	ENSCAFT00030041370.1	UniProtKB/TrEMBL
	ENSCAFT00030041411.1	UniProtKB/TrEMBL
	ENSCAFT00030041447.1	UniProtKB/TrEMBL
	ENSCAFT00040047395.1	UniProtKB/TrEMBL
	ENSCAFT00040047401.1	UniProtKB/TrEMBL
	ENSCAFT00040047415.1	UniProtKB/TrEMBL
	ENSCAFT00040047422.1	UniProtKB/TrEMBL
	ENSCAFT00845032073	ENTREZGENE
	ENSCAFT00845032073.1	UniProtKB/TrEMBL
	ENSCAFT00845032124.1	UniProtKB/TrEMBL
	ENSCAFT00845032172.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	CD28	UniProtKB/TrEMBL
	CTLA4/CD28	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
KEGG Report	cfa:403646	UniProtKB/TrEMBL
NCBI Gene	CD28	ENTREZGENE
PANTHER	PTHR11494	UniProtKB/TrEMBL
	T-CELL-SPECIFIC SURFACE GLYCOPROTEIN CD28	UniProtKB/TrEMBL
Pfam	V-set_2	UniProtKB/TrEMBL
PRINTS	CD28ANTIGEN	UniProtKB/TrEMBL
SMART	IGv	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8C0P7M1_CANLF	UniProtKB/TrEMBL
	A0A8C0PFW8_CANLF	UniProtKB/TrEMBL
	A0A8C0TU71	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TW17_CANLF	UniProtKB/TrEMBL
	A0A8I3S0B0_CANLF	UniProtKB/TrEMBL
	A0A8I3S333_CANLF	UniProtKB/TrEMBL
	A0A8P0T565_CANLF	UniProtKB/TrEMBL
	Q28289_CANLF	UniProtKB/TrEMBL
	Q9GKP3	ENTREZGENE, UniProtKB/TrEMBL
	Q9N0N8	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:38944	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM