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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar granular layer development
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Accession:GO:0021681 term browser browse the term
Definition:The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAIM2 Fas apoptotic inhibitory molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:38,850,588...38,886,614
Ensembl chr12:39,744,700...39,780,702 		JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254 		JBrowse link
G TTBK2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) ARUK-UCL PMID:26323690 NCBI chr15:21,699,674...21,877,481
Ensembl chr15:39,861,102...40,034,982 		JBrowse link
cerebellar granular layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEND1 cell cycle exit and neuronal differentiation 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20153830) MGI
TreeGrafter		 PMID:20153830 GO_REF:0000118 NCBI chr11:804,517...807,608
Ensembl chr11:849,678...850,127 		JBrowse link
cerebellar granular layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE2 serpin family E member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17409116) Ensembl
MGI		 PMID:17409116 GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
cerebellar granular layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF14 kinesin family member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,156,870...176,223,093
Ensembl chr 1:180,462,578...180,526,323 		JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (PMID:9668038) MGI PMID:9668038 NCBI chr 3:10,260,556...10,643,346
Ensembl chr 3:10,611,619...10,738,006 		JBrowse link
G CBLN1 cerebellin 1 precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:29,538,723...29,542,625
Ensembl chr16:48,427,645...48,430,512 		JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:84,663,030...86,170,778
Ensembl chr 4:95,339,460...96,807,748 		JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17984326) Ensembl
MGI		 PMID:17984326 GO_REF:0000107 Ensembl chr10:134,068,936...134,132,964 JBrowse link
G MTPN myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chr 7:127,896,148...127,947,122
Ensembl chr 7:140,392,620...140,443,591 		JBrowse link
G NFIX nuclear factor I X involved_in
acts_upstream_of_or_within		 ISO (PMID:23042739)
(PMID:21800304)		 MGI PMID:21800304 PMID:23042739 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:20537373) BHF-UCL PMID:20537373 NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114 		JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (PMID:10624947) MGI PMID:10624947 NCBI chr12:129,549,399...129,579,087 JBrowse link
G WNT7A Wnt family member 7A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9405095) Ensembl
MGI		 PMID:9405095 GO_REF:0000107 NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16641
    developmental process 6646
      anatomical structure development 6234
        cerebellar granular layer development 18
          cerebellar granular layer maturation 1
          cerebellar granular layer morphogenesis + 14
Path 2
Term Annotations click to browse term
  biological_process 16641
    developmental process 6646
      anatomical structure development 6234
        multicellular organism development 5005
          system development 4349
            nervous system development 2725
              central nervous system development 1167
                brain development 879
                  hindbrain development 223
                    metencephalon development 170
                      cerebellum development 156
                        cerebellar cortex development 69
                          cerebellar granular layer development 18
                            cerebellar granular layer maturation 1
                            cerebellar granular layer morphogenesis + 14
paths to the root