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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer morphogenesis
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Accession:GO:0021683 term browser browse the term
Definition:The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within ISO (MGI:3709698|PMID:17409116) MGI PMID:17409116 MGI:3709698 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
cerebellar granular layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF14 kinesin family member 14 involved_in ISO (MGI:5485315|PMID:23308235) UniProt PMID:23308235 MGI:5485315 NCBI chr 1:176,156,870...176,223,093
Ensembl chr 1:180,462,578...180,526,323
JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chr 3:10,260,556...10,643,346
Ensembl chr 3:10,611,619...10,738,006
JBrowse link
G CBLN1 cerebellin 1 precursor involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr16:29,538,723...29,542,625
Ensembl chr16:48,427,645...48,430,512
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr 4:84,663,030...86,170,778
Ensembl chr 4:95,339,460...96,807,748
JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 acts_upstream_of_or_within ISO (MGI:3769586|PMID:17984326) MGI PMID:17984326 MGI:3769586 Ensembl chr10:134,068,936...134,132,964 JBrowse link
G MTPN myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chr 7:127,896,148...127,947,122
Ensembl chr 7:140,392,620...140,443,591
JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (MGI:5436217|PMID:21800304) MGI PMID:21800304 MGI:5436217 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406
JBrowse link
G NRXN1 neurexin 1 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277
JBrowse link
G OPHN1 oligophrenin 1 involved_in ISO (PMID:27160703) ARUK-UCL PMID:27160703 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114
JBrowse link
G PROX1 prospero homeobox 1 involved_in ISO (MGI:4849596|PMID:20808958) BHF-UCL PMID:20808958 MGI:4849596 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:1351063|PMID:10624947) MGI PMID:10624947 MGI:1351063 NCBI chr12:129,549,399...129,579,087 JBrowse link
G WNT7A Wnt family member 7A acts_upstream_of_or_within ISO (MGI:1195230|PMID:9405095) MGI PMID:9405095 MGI:1195230 NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12654
    developmental process 5903
      anatomical structure morphogenesis 2605
        cerebellar granular layer morphogenesis 14
          cerebellar granular layer formation + 12
          cerebellar granular layer structural organization 1
Path 2
Term Annotations click to browse term
  biological_process 12654
    developmental process 5903
      anatomical structure development 5508
        multicellular organism development 5038
          system development 4740
            nervous system development 2439
              central nervous system development 1176
                brain development 932
                  hindbrain development 216
                    metencephalon development 162
                      cerebellum development 148
                        cerebellum morphogenesis 55
                          cerebellar cortex morphogenesis 44
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation + 12
                              cerebellar granular layer structural organization 1
paths to the root