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ONTOLOGY REPORT - ANNOTATIONS

Term:N-acetylneuraminate metabolic process
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Accession:GO:0006054 term browser browse the term
Definition:The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
Synonyms:exact_synonym: N-acetylneuraminate metabolism
 broad_synonym: sialic acid metabolic process;   sialic acid metabolism


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N-acetylneuraminate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmah cytidine monophospho-N-acetylneuraminic acid hydroxylase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275 		JBrowse link
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase involved_in IEA
ISO		 GO_REF:0000041
MGI:6281181 (PMID:30382946)		 UniProt
RGD		 PMID:30382946 GO_REF:0000041 NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase involved_in ISO MGI:6281181 (PMID:30382946) RGD PMID:30382946 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase involved_in ISO MGI:6281181 (PMID:30382946) RGD PMID:30382946 NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648 		JBrowse link
G Nans N-acetylneuraminate synthase involved_in ISO MGI:6281181 (PMID:30382946) RGD PMID:30382946 NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950 		JBrowse link
G Slc35a1 solute carrier family 35 member A1 involved_in ISO MGI:6281181 (PMID:30382946) RGD PMID:30382946 NCBI chr 5:49,225,599...49,248,382
Ensembl chr 5:49,225,602...49,248,335 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (PMID:19820709) RGD PMID:19820709 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23999306)		 UniProt
RGD		 PMID:23999306 GO_REF:0000024 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310 		JBrowse link
N-acetylneuraminate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase involved_in TAS
IEA
IC
ISO		 GO_REF:0000107
PMID:9305887
(PMID:14707127), (PMID:31121216)
MGI:2182685|MGI:3713799 (PMID:11929971), (PMID:17549255)		 Ensembl
RGD		 PMID:11929971 PMID:14707127 PMID:17549255 PMID:31121216 PMID:15330759 More... GO_REF:0000107, RGD:1358725, RGD:401901241 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase involved_in ISO
IDA
IBA		 (PMID:16237198)
GO_REF:0000033		 RGD
GO_Central		 PMID:16237198 PMID:16237198 GO_REF:0000033, RGD:8554804 NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648 		JBrowse link
G Nans N-acetylneuraminate synthase involved_in ISO (PMID:31121216) RGD PMID:31121216 NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950 		JBrowse link
N-acetylneuraminate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd2 amidohydrolase domain containing 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095 		JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486 		JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:38,520,663...38,538,713
Ensembl chr14:38,520,705...38,538,713 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase involved_in IEA
IBA
ISO
ISS		 GO_REF:0000041
GO_REF:0000033
(PMID:11737202)
(PMID:33895133)
GO_REF:0000024		 UniProt
GO_Central
RGD		 PMID:11737202 PMID:33895133 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372 		JBrowse link
G Renbp renin binding protein involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        amide metabolic process 467
          N-acetylneuraminate metabolic process 15
            N-acetylneuraminate biosynthetic process 3
            N-acetylneuraminate catabolic process 7
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        small molecule metabolic process 1916
          organic acid metabolic process 1046
            oxoacid metabolic process 1033
              carboxylic acid metabolic process 1018
                N-acetylneuraminate metabolic process 15
                  N-acetylneuraminate biosynthetic process 3
                  N-acetylneuraminate catabolic process 7
paths to the root