Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cysteine-type deubiquitinase activity
go back to main search page
Accession:GO:0004843 term browser browse the term
Definition:An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
Synonyms:exact_synonym: deubiquitinase;   deubiquitylase;   thiol-dependent deubiquitinase;   thiol-dependent ubiquitin-specific protease activity;   thiol-dependent ubiquitinyl hydrolase activity;   ubiquitin hydrolase activity
 narrow_synonym: UBP;   UCH2;   deubiquitinase activity;   deubiquitinating enzyme;   ubiquitinyl hydrolase 1 activity
 broad_synonym: ubiquitin-specific protease activity;   ubiquitinyl hydrolase activity
 related_synonym: ubiquitin C-terminal hydrolase
 alt_id: GO:0036459
 xref: EC:3.4.19.12;   Reactome:R-HSA-3640872 "USP34 deubiquitinates AXIN1,AXIN2";   Reactome:R-HSA-5688797 "ATXN3 family cleave Ub chains";   Reactome:R-HSA-5688837 "ATXN3 deubiquitinates polyUb-PARK2";   Reactome:R-HSA-5689950 "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN";   Reactome:R-HSA-5689972 "USP2 deubiquitinates MDM2,MDM4";   Reactome:R-HSA-5689973 "USP10,USP24,USP42 deubiquitinate TP53";   Reactome:R-HSA-5690080 "USP3,SAGA deubiquitinate Histone H2A,H2B";   Reactome:R-HSA-5690152 "USP5 cleaves polyubiquitin";   Reactome:R-HSA-5690157 "USP16,USP21 deubiquitinate Histone H2A";   Reactome:R-HSA-5690159 "USP21 deubiquitinates RIPK1,DDX58";   Reactome:R-HSA-5690196 "USP8 deubiquitinates RNF128";   Reactome:R-HSA-5690319 "UCHL1, UCHL3 cleave ubiquitin adducts";   Reactome:R-HSA-5690759 "BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1";   Reactome:R-HSA-5690790 "Histone H2A is dubiquitinated by the PR-DUB complex";   Reactome:R-HSA-5691381 "MYSM1 deubiquitinates Histone H2A";   Reactome:R-HSA-5696534 "USP18 deubiquitinates TAK1:TAB1";   Reactome:R-HSA-5696564 "USP25 deubiquitinates DDX58";   Reactome:R-HSA-5696600 "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1";   Reactome:R-HSA-5696605 "USP12, USP26 deubiquitinate AR";   Reactome:R-HSA-5696627 "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG";   Reactome:R-HSA-5696872 "USP30 deubiquitinates Ub-MOM proteins";   Reactome:R-HSA-5696914 "USP28 deubiquitinates CLSPN and MYC";   Reactome:R-HSA-5696945 "USP33 deubiquitinates CCP110,ARRB";   Reactome:R-HSA-5696947 "USP47 deubiquitinates POLB";   Reactome:R-HSA-5696958 "USP44 deubiquitinates CDC20";   Reactome:R-HSA-5696960 "USP49 deubiquitinates H2B";   Reactome:R-HSA-5696968 "USP20, USP33 deubiquitinate ADRB2";   Reactome:R-HSA-5696997 "USP24 deubiquitinates DDB2";   Reactome:R-HSA-5697009 "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2";   Reactome:R-HSA-6781764 "USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1";   Reactome:R-HSA-6781779 "USP13 deubiquitinates BECN1,USP10";   Reactome:R-HSA-6781814 "USP19 deubiquitinates RNF123";   Reactome:R-HSA-6781897 "USP11 deubiquitinates NFKBIA";   Reactome:R-HSA-6782106 "USP10 deubiquitinates SNX3, CFTR";   Reactome:R-HSA-6782628 "USP8 deubiquitinates STAM2:HGS";   Reactome:R-HSA-6782820 "USP17 deubiquitinates SUDS3";   Reactome:R-HSA-6783177 "USP21 deubiquitinates GATA3,IL33";   Reactome:R-HSA-870437 "USP9X (FAM) deubiquitinates SMAD4";   Reactome:R-HSA-8862184 "USP48 cleaves polyubiquitin";   Reactome:R-HSA-8865182 "OTUD7A hydrolyses K11diUb";   Reactome:R-HSA-8869456 "USP4 deubiquitinate TRAF2,TRAF6";   Reactome:R-HSA-8873946 "OTUD3 deubiquitinates PTEN";   Reactome:R-HSA-9033478 "USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin";   Reactome:R-HSA-9033491 "USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin";   Reactome:R-HSA-9653514 "USP17L2 deubiquitinates RCE1";   reactome:R-HSA-1358795 "Deubiquitination of RNF41 by P-USP8";   reactome:R-HSA-2179291 "UCHL5, USP15 deubiquitinate TGFBR1";   reactome:R-HSA-3215295 "USP7 deubiquitinates MDM2";   reactome:R-HSA-3215310 "USP7 deubiquitinates TP53 and counteracts MDM2";   reactome:R-HSA-4641236 "USP8 deubiquitinates FZD to potentiate WNT signaling";   reactome:R-HSA-5653770 "USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA";   reactome:R-HSA-5655466 "USP1:WDR48 deubiquitinates monoUb:K164-PCNA";   reactome:R-HSA-5696465 "USP45 deubiquitinates ERCC1";   reactome:R-HSA-6782069 "UVSSA:USP7 deubiquitinates ERCC6";   reactome:R-HSA-6786171 "FANCD2 deubiquitination by USP1:WDR48";   reactome:R-HSA-6807118 "USP7 deubiquitinates monoubiquitinated PTEN";   reactome:R-HSA-6807206 "USP13 and OTUD3 deubiquitinate PTEN";   reactome:R-HSA-8853503 "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin";   reactome:R-HSA-8853514 "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin";   reactome:R-HSA-8853515 "OTULIN,USP5 cleaves UBC yielding ubiquitin";   reactome:R-HSA-8853529 "OTULIN,USP5 cleaves UBB yielding ubiquitin";   reactome:R-HSA-8875443 "USP8 deubiquitinates LRIG1";   reactome:R-HSA-8986083 "USP33 deubiquitinates ROBO1"

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
cysteine-type deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg13 ALG13 UDP-N-acetylglucosaminyltransferase subunit NOT|enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955490:4,069,866...4,140,494
Ensembl chrNW_004955490:4,069,494...4,140,532 		JBrowse link
G Atxn3 ataxin 3 enables ISO (PMID:33157014)
(PMID:21855799)		 UniProt PMID:21855799 PMID:33157014 NCBI chrNW_004955438:14,405,415...14,443,457
Ensembl chrNW_004955438:14,405,643...14,440,009 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 enables ISO (PMID:18757409), (PMID:19188440), (PMID:19815555), (PMID:20436459), (PMID:24703950) UniProt PMID:18757409 PMID:19188440 PMID:19815555 PMID:20436459 PMID:24703950 NCBI chrNW_004955430:2,391,970...2,400,645
Ensembl chrNW_004955430:2,390,524...2,400,645 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase enables ISO (PMID:18313383), (PMID:18636086), (PMID:27458237), (PMID:27591049)
(PMID:28701375)		 UniProt PMID:18313383 PMID:18636086 PMID:27458237 PMID:27591049 PMID:28701375 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925 		JBrowse link
G Desi2 desumoylating isopeptidase 2 enables ISO (PMID:28483520) FlyBase PMID:28483520 NCBI chrNW_004955406:7,881,815...7,894,690
Ensembl chrNW_004955406:7,880,648...7,894,629 		JBrowse link
G Eif3f eukaryotic translation initiation factor 3 subunit F enables ISO (PMID:21124883) FlyBase PMID:21124883 NCBI chrNW_004955414:23,805,406...23,812,776
Ensembl chrNW_004955414:23,804,705...23,817,044 		JBrowse link
G Josd2 Josephin domain containing 2 enables ISO (PMID:21118805) UniProt PMID:21118805 NCBI chrNW_004955559:655,178...659,412
Ensembl chrNW_004955559:655,178...659,412 		JBrowse link
G Mindy3 MINDY lysine 48 deubiquitinase 3 enables ISO (PMID:27292798) UniProt PMID:27292798 NCBI chrNW_004955429:11,805,205...11,890,103
Ensembl chrNW_004955429:11,805,080...11,890,103 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 enables ISO (PMID:18954305), (PMID:19211026), (PMID:23827681) UniProt PMID:18954305 PMID:19211026 PMID:23827681 NCBI chrNW_004955422:21,047,184...21,055,596
Ensembl chrNW_004955422:21,047,184...21,055,616 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 enables ISO (PMID:15258613)
(PMID:18954305), (PMID:23827681)		 UniProt PMID:15258613 PMID:18954305 PMID:23827681 NCBI chrNW_004955438:16,079,859...16,096,686
Ensembl chrNW_004955438:16,079,860...16,096,686 		JBrowse link
G Otud1 OTU deubiquitinase 1 enables ISO (PMID:23827681), (PMID:36445135) UniProt PMID:23827681 PMID:36445135 NCBI chrNW_004955429:5,588,333...5,590,220 JBrowse link
G Otud3 OTU deubiquitinase 3 enables ISO (PMID:26280536)
(PMID:23827681), (PMID:26280536), (PMID:32011234), (PMID:35675826)		 MGI
UniProt		 PMID:23827681 PMID:26280536 PMID:32011234 PMID:35675826 NCBI chrNW_004955452:488,295...516,162
Ensembl chrNW_004955452:487,994...516,217 		JBrowse link
G Otud4 OTU deubiquitinase 4 enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955428:1,062,998...1,108,711
Ensembl chrNW_004955428:1,062,998...1,115,415 		JBrowse link
G Otud5 OTU deubiquitinase 5 enables ISO (PMID:22245969), (PMID:23827681), (PMID:33110214) UniProt PMID:22245969 PMID:23827681 PMID:33110214 NCBI chrNW_004955543:452,172...484,564
Ensembl chrNW_004955543:452,121...484,560 		JBrowse link
G Otud6a OTU deubiquitinase 6A enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955475:9,626,733...9,629,841 JBrowse link
G Otud6b OTU deubiquitinase 6B enables ISO (PMID:21267069) UniProt PMID:21267069 NCBI chrNW_004955417:7,844,311...7,859,032
Ensembl chrNW_004955417:7,844,292...7,858,658 		JBrowse link
G Otud7a OTU deubiquitinase 7A enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955416:30,244,875...30,427,829 JBrowse link
G Otud7b OTU deubiquitinase 7B enables ISO (PMID:12682062)
(PMID:23827681), (PMID:28489822)
(PMID:23334419)		 MGI
UniProt		 PMID:12682062 PMID:23334419 PMID:23827681 PMID:28489822 NCBI chrNW_004955413:758,098...812,605
Ensembl chrNW_004955413:751,546...812,605 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity enables ISO (PMID:23746843), (PMID:23806334), (PMID:23827681), (PMID:24726323), (PMID:24726327), (PMID:26997266), (PMID:27523608), (PMID:27559085)
(PMID:23708998), (PMID:27523608), (PMID:29950720)
(PMID:35170849), (PMID:35587511)
(PMID:26235645)		 UniProt
Reactome		 PMID:23708998 PMID:23746843 PMID:23806334 PMID:23827681 PMID:24726323 More... NCBI chrNW_004955426:3,953,852...3,982,532
Ensembl chrNW_004955426:3,953,933...3,982,175 		JBrowse link
G Tank TRAF family member associated NFKB activator contributes_to ISO (PMID:25861989) UniProtKB PMID:25861989 NCBI chrNW_004955449:12,470,203...12,561,364
Ensembl chrNW_004955449:12,470,085...12,561,370 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 enables ISO (PMID:15258597), (PMID:23827681) UniProt PMID:15258597 PMID:23827681 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 enables ISO (PMID:9521656)
(PMID:12913066)
(PMID:34244144)		 UniProt
MGI
FlyBase		 PMID:9521656 PMID:12913066 PMID:34244144 NCBI chrNW_004955443:6,367,519...6,379,638
Ensembl chrNW_004955443:6,367,460...6,380,462 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 enables ISO (PMID:19047059), (PMID:9521656)
(PMID:26235645)		 UniProt
Reactome		 PMID:9521656 PMID:19047059 PMID:26235645 NCBI chrNW_004955404:31,414,076...31,465,205
Ensembl chrNW_004955404:31,414,208...31,464,968 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 enables ISO (PMID:28992318)
(PMID:18922472)		 FlyBase
UniProt		 PMID:18922472 PMID:28992318 NCBI chrNW_004955406:30,432,652...30,468,741 JBrowse link
G Usp1 ubiquitin specific peptidase 1 enables ISO (PMID:18082604)
(PMID:20129063)		 UniProt PMID:18082604 PMID:20129063 NCBI chrNW_004955423:27,236,242...27,254,064
Ensembl chrNW_004955423:27,237,003...27,251,892 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 enables ISO (PMID:19398555), (PMID:25861989)
(PMID:20096447), (PMID:21962518), (PMID:31981475), (PMID:34348161), (PMID:34469731)		 UniProt PMID:19398555 PMID:20096447 PMID:21962518 PMID:25861989 PMID:31981475 More... NCBI chrNW_004955541:242,182...296,018
Ensembl chrNW_004955541:242,091...296,059 		JBrowse link
G Usp11 ubiquitin specific peptidase 11 enables ISO (PMID:15314155) UniProt PMID:15314155 NCBI chrNW_004955516:840,708...858,201
Ensembl chrNW_004955516:841,114...857,322 		JBrowse link
G Usp12 ubiquitin specific peptidase 12 enables ISO (PMID:19075014) UniProt PMID:19075014 NCBI chrNW_004955497:6,524,487...6,613,403
Ensembl chrNW_004955497:6,524,487...6,556,675 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 enables ISO (PMID:21811243), (PMID:21962518), (PMID:22216260), (PMID:26280536) UniProt PMID:21811243 PMID:21962518 PMID:22216260 PMID:26280536 NCBI chrNW_004955420:8,835,858...8,919,837
Ensembl chrNW_004955420:8,835,549...8,919,933 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 enables ISO (PMID:19106094), (PMID:23958854) UniProt PMID:19106094 PMID:23958854 NCBI chrNW_004955402:9,710,080...9,737,601
Ensembl chrNW_004955402:9,710,080...9,743,077 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 enables ISO (PMID:12532266)
(PMID:16005295), (PMID:21947082), (PMID:22344298), (PMID:24526689), (PMID:27368102), (PMID:33093067)
PMID:10880343		 RGD
MGI
UniProt		 PMID:10880343 PMID:12532266 PMID:16005295 PMID:21947082 PMID:22344298 More... RGD:634484 NCBI chrNW_004955458:9,440,645...9,533,653
Ensembl chrNW_004955458:9,403,097...9,533,653 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 enables ISO (PMID:17914355), (PMID:32129764) UniProt PMID:17914355 PMID:32129764 NCBI chrNW_004955407:28,375,246...28,413,279 JBrowse link
G Usp19 ubiquitin specific peptidase 19 enables ISO (PMID:24356957)
(PMID:21971047)
(PMID:19465887)		 ParkinsonsUK-UCL
UniProt		 PMID:19465887 PMID:21971047 PMID:24356957 NCBI chrNW_004955532:1,104,212...1,115,267
Ensembl chrNW_004955532:1,104,591...1,113,567 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 enables ISO (PMID:17290220)
PMID:10938131
(PMID:19917254)		 FlyBase
UniProt		 PMID:10938131 PMID:17290220 PMID:19917254 RGD:634247 NCBI chrNW_004955412:20,435,778...20,461,898
Ensembl chrNW_004955412:20,433,302...20,457,493 		JBrowse link
G Usp20 ubiquitin specific peptidase 20 enables ISO (PMID:19424180), (PMID:26839314), (PMID:29487085) UniProt PMID:19424180 PMID:26839314 PMID:29487085 NCBI chrNW_004955513:43,601...70,714
Ensembl chrNW_004955513:42,809...70,906 		JBrowse link
G Usp21 ubiquitin specific peptidase 21 enables ISO (PMID:26100909)
(PMID:18172164)
(PMID:10799498), (PMID:32011234)		 UniProt PMID:10799498 PMID:18172164 PMID:26100909 PMID:32011234 NCBI chrNW_004955468:12,923,121...12,929,780
Ensembl chrNW_004955468:12,924,574...12,929,497 		JBrowse link
G Usp22 ubiquitin specific peptidase 22 contributes_to
enables		 ISO (PMID:18206973)
(PMID:16378762)
(PMID:16378762), (PMID:32130408)		 UniProtKB
MGI
UniProt		 PMID:16378762 PMID:18206973 PMID:32130408 NCBI chrNW_004955577:979,317...1,002,478
Ensembl chrNW_004955577:978,152...1,002,480 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 enables ISO (PMID:18538659) UniProt PMID:18538659 NCBI chrNW_004955407:17,429,299...17,572,138
Ensembl chrNW_004955407:17,429,299...17,575,262 		JBrowse link
G Usp27x ubiquitin specific peptidase 27 X-linked enables ISO (PMID:27013495) UniProt PMID:27013495 NCBI chrNW_004955543:1,023,931...1,027,048 JBrowse link
G Usp28 ubiquitin specific peptidase 28 enables ISO (PMID:16901786), (PMID:17558397) UniProt PMID:16901786 PMID:17558397 NCBI chrNW_004955412:15,425,136...15,469,819
Ensembl chrNW_004955412:15,426,159...15,443,023 		JBrowse link
G Usp3 ubiquitin specific peptidase 3 enables ISO (PMID:17980597) UniProt PMID:17980597 NCBI chrNW_004955450:11,729,433...11,802,462
Ensembl chrNW_004955450:11,727,104...11,802,462 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 enables ISO (PMID:14715245), (PMID:24896179), (PMID:25621951)
(PMID:24513856)		 UniProt PMID:14715245 PMID:24513856 PMID:24896179 PMID:25621951 NCBI chrNW_004955455:10,234,779...10,257,959
Ensembl chrNW_004955455:10,192,426...10,257,951 		JBrowse link
G Usp31 ubiquitin specific peptidase 31 enables ISO (PMID:16214042) FlyBase PMID:16214042 NCBI chrNW_004955493:1,663,268...1,724,522
Ensembl chrNW_004955493:1,663,268...1,702,386 		JBrowse link
G Usp32 ubiquitin specific peptidase 32 enables ISO (PMID:20549504), (PMID:36476874) UniProt PMID:20549504 PMID:36476874 NCBI chrNW_004955451:1,511,687...1,678,546 JBrowse link
G Usp33 ubiquitin specific peptidase 33 enables ISO (PMID:23486064)
(PMID:24056301)		 UniProt PMID:23486064 PMID:24056301 NCBI chrNW_004955423:15,424,349...15,469,344
Ensembl chrNW_004955423:15,423,932...15,469,344 		JBrowse link
G Usp34 ubiquitin specific peptidase 34 enables ISO (PMID:14715245), (PMID:21383061) UniProt PMID:14715245 PMID:21383061 NCBI chrNW_004955424:22,434,292...22,689,944
Ensembl chrNW_004955424:22,474,098...22,689,322 		JBrowse link
G Usp35 ubiquitin specific peptidase 35 enables ISO (PMID:14715245) FlyBase PMID:14715245 NCBI chrNW_004955414:13,755,604...13,779,049
Ensembl chrNW_004955414:13,756,488...13,772,052 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 enables ISO (PMID:14715245) FlyBase PMID:14715245 NCBI chrNW_004955506:3,824,598...3,861,919
Ensembl chrNW_004955506:3,824,556...3,862,098 		JBrowse link
G Usp37 ubiquitin specific peptidase 37 enables ISO (PMID:14715245), (PMID:21596315) FlyBase PMID:14715245 PMID:21596315 NCBI chrNW_004955453:14,846,044...14,931,336
Ensembl chrNW_004955453:14,846,044...14,931,336 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 enables ISO (PMID:14715245), (PMID:27692986) FlyBase PMID:14715245 PMID:27692986 NCBI chrNW_004955471:316,319...350,982
Ensembl chrNW_004955471:315,779...350,982 		JBrowse link
G Usp39 ubiquitin specific peptidase 39 NOT|enables ISO (PMID:18728397) FlyBase PMID:18728397 NCBI chrNW_004955424:1,867,910...1,893,338
Ensembl chrNW_004955424:1,867,850...1,894,157 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 enables ISO (PMID:16316627), (PMID:16472766), (PMID:18728397), (PMID:30514904) UniProt PMID:16316627 PMID:16472766 PMID:18728397 PMID:30514904 NCBI chrNW_004955532:1,247,110...1,284,564
Ensembl chrNW_004955532:1,247,110...1,285,121 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 enables ISO (PMID:14715245), (PMID:17443180), (PMID:20402667)
(PMID:17443180), (PMID:20402667)		 FlyBase
UniProt		 PMID:14715245 PMID:17443180 PMID:20402667 NCBI chrNW_004955405:31,977,045...32,006,733
Ensembl chrNW_004955405:31,977,602...32,006,810 		JBrowse link
G Usp45 ubiquitin specific peptidase 45 enables ISO (PMID:14715245)
(PMID:25538220), (PMID:30258100)		 FlyBase
UniProt		 PMID:14715245 PMID:25538220 PMID:30258100 NCBI chrNW_004955411:25,315,536...25,375,283
Ensembl chrNW_004955411:25,316,535...25,378,573 		JBrowse link
G Usp46 ubiquitin specific peptidase 46 enables ISO (PMID:14715245), (PMID:19075014) FlyBase PMID:14715245 PMID:19075014 NCBI chrNW_004955447:17,915,451...17,975,149
Ensembl chrNW_004955447:17,900,611...17,971,601 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 enables ISO (PMID:21362556), (PMID:36749823) FlyBase PMID:21362556 PMID:36749823 NCBI chrNW_004955414:27,357,602...27,462,481
Ensembl chrNW_004955414:27,357,602...27,462,731 		JBrowse link
G Usp49 ubiquitin specific peptidase 49 enables ISO (PMID:14715245), (PMID:23824326), (PMID:28363942) UniProt PMID:14715245 PMID:23824326 PMID:28363942 NCBI chrNW_004955437:8,187,118...8,237,910
Ensembl chrNW_004955437:8,191,236...8,198,809 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 enables ISO (PMID:24424410)
(PMID:26235645)		 ParkinsonsUK-UCL
Reactome		 PMID:24424410 PMID:26235645 NCBI chrNW_004955413:4,451,530...4,466,832
Ensembl chrNW_004955413:4,451,622...4,466,832 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 enables ISO (PMID:28094437), (PMID:36876523) UniProt PMID:28094437 PMID:36876523 NCBI chrNW_004955409:3,788,723...3,838,077
Ensembl chrNW_004955409:3,788,903...3,837,983 		JBrowse link
G Usp53 ubiquitin specific peptidase 53 NOT|enables ISO (PMID:14715245) UniProt PMID:14715245 NCBI chrNW_004955428:20,957,807...21,023,380
Ensembl chrNW_004955428:20,957,807...21,023,380 		JBrowse link
G Usp54 ubiquitin specific peptidase 54 enables ISO (PMID:36590171) UniProt PMID:36590171 NCBI chrNW_004955437:18,240,303...18,322,197
Ensembl chrNW_004955437:18,258,024...18,321,481 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 enables ISO (PMID:21268065)
(PMID:27863226)
(PMID:16964248), (PMID:21745816), (PMID:26280536), (PMID:28655758), (PMID:35216969)
(PMID:26235645)
(PMID:11923872), (PMID:26678539)		 RGD
UniProt
Reactome		 PMID:11923872 PMID:16328052 PMID:16964248 PMID:21268065 PMID:21745816 More... RGD:2316130 NCBI chrNW_004955442:9,316,022...9,355,751
Ensembl chrNW_004955442:9,315,225...9,356,393 		JBrowse link
G Usp8 ubiquitin specific peptidase 8 enables ISO (PMID:16520378), (PMID:18388320), (PMID:18728397), (PMID:27444016)
(PMID:11500497), (PMID:15342353), (PMID:16120644), (PMID:16771824)		 MGI
UniProt		 PMID:11500497 PMID:15342353 PMID:16120644 PMID:16520378 PMID:16771824 More... NCBI chrNW_004955409:3,839,308...3,903,595
Ensembl chrNW_004955409:3,840,007...3,891,284 		JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked enables ISO (PMID:22371489), (PMID:26235645)
(PMID:12895410)		 Reactome
UniProt		 PMID:12895410 PMID:22371489 PMID:26235645 NCBI chrNW_004955565:1,479,040...1,602,070
Ensembl chrNW_004955565:1,479,040...1,602,070 		JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 enables ISO PMID:15037600
(PMID:23827681), (PMID:32649882)		 RGD
UniProt		 PMID:15037600 PMID:23827681 PMID:32649882 RGD:1302353 NCBI chrNW_004955444:12,542,479...12,567,971
Ensembl chrNW_004955444:12,542,479...12,567,971 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A contributes_to ISO (PMID:25861989) UniProtKB PMID:25861989 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959 		JBrowse link
G Zranb1 zinc finger RANBP2-type containing 1 enables ISO (PMID:18281465)
(PMID:18281465), (PMID:23827681), (PMID:25752573), (PMID:25752577)		 UniProt PMID:18281465 PMID:23827681 PMID:25752573 PMID:25752577 NCBI chrNW_004955477:2,864,737...2,922,069
Ensembl chrNW_004955477:2,873,170...2,922,069 		JBrowse link
Met1-linked polyubiquitin deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase enables ISO (PMID:26997266) Reactome PMID:26997266 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14359
    catalytic activity 3751
      hydrolase activity 1337
        peptidase activity 355
          cysteine-type peptidase activity 110
            cysteine-type deubiquitinase activity 67
              Met1-linked polyubiquitin deubiquitinase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 14359
    catalytic activity 3751
      hydrolase activity 1337
        peptidase activity 355
          ubiquitin-like protein peptidase activity 90
            deubiquitinase activity 78
              cysteine-type deubiquitinase activity 67
                Met1-linked polyubiquitin deubiquitinase activity 1
paths to the root