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ONTOLOGY REPORT - ANNOTATIONS


Term:cysteine-type deubiquitinase activity
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Accession:GO:0004843 term browser browse the term
Definition:An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
Synonyms:exact_synonym: deubiquitinase;   deubiquitylase;   thiol-dependent deubiquitinase;   thiol-dependent ubiquitin-specific protease activity;   thiol-dependent ubiquitinyl hydrolase activity;   ubiquitin hydrolase activity
 narrow_synonym: UBP;   UCH2;   deubiquitinase activity;   deubiquitinating enzyme;   ubiquitinyl hydrolase 1 activity
 broad_synonym: ubiquitin-specific protease activity;   ubiquitinyl hydrolase activity
 related_synonym: ubiquitin C-terminal hydrolase
 alt_id: GO:0036459
 xref: EC:3.4.19.12;   Reactome:R-HSA-3640872 "USP34 deubiquitinates AXIN1,AXIN2";   Reactome:R-HSA-5688797 "ATXN3 family cleave Ub chains";   Reactome:R-HSA-5688837 "ATXN3 deubiquitinates polyUb-PARK2";   Reactome:R-HSA-5689950 "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN";   Reactome:R-HSA-5689972 "USP2 deubiquitinates MDM2,MDM4";   Reactome:R-HSA-5689973 "USP10,USP24,USP42 deubiquitinate TP53";   Reactome:R-HSA-5690080 "USP3,SAGA deubiquitinate Histone H2A,H2B";   Reactome:R-HSA-5690152 "USP5 cleaves polyubiquitin";   Reactome:R-HSA-5690157 "USP16,USP21 deubiquitinate Histone H2A";   Reactome:R-HSA-5690159 "USP21 deubiquitinates RIPK1,DDX58";   Reactome:R-HSA-5690196 "USP8 deubiquitinates RNF128";   Reactome:R-HSA-5690319 "UCHL1, UCHL3 cleave ubiquitin adducts";   Reactome:R-HSA-5690759 "BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1";   Reactome:R-HSA-5690790 "Histone H2A is dubiquitinated by the PR-DUB complex";   Reactome:R-HSA-5691381 "MYSM1 deubiquitinates Histone H2A";   Reactome:R-HSA-5696534 "USP18 deubiquitinates TAK1:TAB1";   Reactome:R-HSA-5696564 "USP25 deubiquitinates DDX58";   Reactome:R-HSA-5696600 "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1";   Reactome:R-HSA-5696605 "USP12, USP26 deubiquitinate AR";   Reactome:R-HSA-5696627 "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG";   Reactome:R-HSA-5696872 "USP30 deubiquitinates Ub-MOM proteins";   Reactome:R-HSA-5696914 "USP28 deubiquitinates CLSPN and MYC";   Reactome:R-HSA-5696945 "USP33 deubiquitinates CCP110,ARRB";   Reactome:R-HSA-5696947 "USP47 deubiquitinates POLB";   Reactome:R-HSA-5696958 "USP44 deubiquitinates CDC20";   Reactome:R-HSA-5696960 "USP49 deubiquitinates H2B";   Reactome:R-HSA-5696968 "USP20, USP33 deubiquitinate ADRB2";   Reactome:R-HSA-5696997 "USP24 deubiquitinates DDB2";   Reactome:R-HSA-5697009 "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2";   Reactome:R-HSA-6781764 "USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1";   Reactome:R-HSA-6781779 "USP13 deubiquitinates BECN1,USP10";   Reactome:R-HSA-6781814 "USP19 deubiquitinates RNF123";   Reactome:R-HSA-6781897 "USP11 deubiquitinates NFKBIA";   Reactome:R-HSA-6782106 "USP10 deubiquitinates SNX3, CFTR";   Reactome:R-HSA-6782628 "USP8 deubiquitinates STAM2:HGS";   Reactome:R-HSA-6782820 "USP17 deubiquitinates SUDS3";   Reactome:R-HSA-6783177 "USP21 deubiquitinates GATA3,IL33";   Reactome:R-HSA-870437 "USP9X (FAM) deubiquitinates SMAD4";   Reactome:R-HSA-8862184 "USP48 cleaves polyubiquitin";   Reactome:R-HSA-8865182 "OTUD7A hydrolyses K11diUb";   Reactome:R-HSA-8869456 "USP4 deubiquitinate TRAF2,TRAF6";   Reactome:R-HSA-8873946 "OTUD3 deubiquitinates PTEN";   Reactome:R-HSA-9033478 "USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin";   Reactome:R-HSA-9033491 "USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin";   Reactome:R-HSA-9653514 "USP17L2 deubiquitinates RCE1";   reactome:R-HSA-1358795 "Deubiquitination of RNF41 by P-USP8";   reactome:R-HSA-2179291 "UCHL5, USP15 deubiquitinate TGFBR1";   reactome:R-HSA-3215295 "USP7 deubiquitinates MDM2";   reactome:R-HSA-3215310 "USP7 deubiquitinates TP53 and counteracts MDM2";   reactome:R-HSA-4641236 "USP8 deubiquitinates FZD to potentiate WNT signaling";   reactome:R-HSA-5653770 "USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA";   reactome:R-HSA-5655466 "USP1:WDR48 deubiquitinates monoUb:K164-PCNA";   reactome:R-HSA-5696465 "USP45 deubiquitinates ERCC1";   reactome:R-HSA-6782069 "UVSSA:USP7 deubiquitinates ERCC6";   reactome:R-HSA-6786171 "FANCD2 deubiquitination by USP1:WDR48";   reactome:R-HSA-6807118 "USP7 deubiquitinates monoubiquitinated PTEN";   reactome:R-HSA-6807206 "USP13 and OTUD3 deubiquitinate PTEN";   reactome:R-HSA-8853503 "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin";   reactome:R-HSA-8853514 "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin";   reactome:R-HSA-8853515 "OTULIN,USP5 cleaves UBC yielding ubiquitin";   reactome:R-HSA-8853529 "OTULIN,USP5 cleaves UBB yielding ubiquitin";   reactome:R-HSA-8875443 "USP8 deubiquitinates LRIG1";   reactome:R-HSA-8986083 "USP33 deubiquitinates ROBO1"


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cysteine-type deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg13 ALG13 UDP-N-acetylglucosaminyltransferase subunit NOT|enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955490:4,069,866...4,140,494
Ensembl chrNW_004955490:4,069,494...4,140,532
JBrowse link
G Atxn3 ataxin 3 enables ISO (PMID:33157014)
(PMID:21855799)
UniProt PMID:21855799 PMID:33157014 NCBI chrNW_004955438:14,405,415...14,443,457
Ensembl chrNW_004955438:14,405,643...14,440,009
JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 enables ISO (PMID:18757409), (PMID:19188440), (PMID:19815555), (PMID:20436459), (PMID:24703950) UniProt PMID:18757409 PMID:19188440 PMID:19815555 PMID:20436459 PMID:24703950 NCBI chrNW_004955430:2,391,970...2,400,645
Ensembl chrNW_004955430:2,390,524...2,400,645
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase enables ISO (PMID:18313383), (PMID:18636086), (PMID:27458237), (PMID:27591049)
(PMID:28701375)
UniProt PMID:18313383 PMID:18636086 PMID:27458237 PMID:27591049 PMID:28701375 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925
JBrowse link
G Desi2 desumoylating isopeptidase 2 enables ISO (PMID:28483520) FlyBase PMID:28483520 NCBI chrNW_004955406:7,881,815...7,894,690
Ensembl chrNW_004955406:7,880,648...7,894,629
JBrowse link
G Eif3f eukaryotic translation initiation factor 3 subunit F enables ISO (PMID:21124883) FlyBase PMID:21124883 NCBI chrNW_004955414:23,805,406...23,812,776
Ensembl chrNW_004955414:23,804,705...23,817,044
JBrowse link
G Josd2 Josephin domain containing 2 enables ISO (PMID:21118805) UniProt PMID:21118805 NCBI chrNW_004955559:655,178...659,412
Ensembl chrNW_004955559:655,178...659,412
JBrowse link
G Mindy3 MINDY lysine 48 deubiquitinase 3 enables ISO (PMID:27292798) UniProt PMID:27292798 NCBI chrNW_004955429:11,805,205...11,890,103
Ensembl chrNW_004955429:11,805,080...11,890,103
JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 enables ISO (PMID:18954305), (PMID:19211026), (PMID:23827681) UniProt PMID:18954305 PMID:19211026 PMID:23827681 NCBI chrNW_004955422:21,047,184...21,055,596
Ensembl chrNW_004955422:21,047,184...21,055,616
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 enables ISO (PMID:15258613)
(PMID:18954305), (PMID:23827681)
UniProt PMID:15258613 PMID:18954305 PMID:23827681 NCBI chrNW_004955438:16,079,859...16,096,686
Ensembl chrNW_004955438:16,079,860...16,096,686
JBrowse link
G Otud1 OTU deubiquitinase 1 enables ISO (PMID:23827681), (PMID:36445135) UniProt PMID:23827681 PMID:36445135 NCBI chrNW_004955429:5,588,333...5,590,220 JBrowse link
G Otud3 OTU deubiquitinase 3 enables ISO (PMID:26280536)
(PMID:23827681), (PMID:26280536), (PMID:32011234), (PMID:35675826)
MGI
UniProt
PMID:23827681 PMID:26280536 PMID:32011234 PMID:35675826 NCBI chrNW_004955452:488,295...516,162
Ensembl chrNW_004955452:487,994...516,217
JBrowse link
G Otud4 OTU deubiquitinase 4 enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955428:1,062,998...1,108,711
Ensembl chrNW_004955428:1,062,998...1,115,415
JBrowse link
G Otud5 OTU deubiquitinase 5 enables ISO (PMID:22245969), (PMID:23827681), (PMID:33110214) UniProt PMID:22245969 PMID:23827681 PMID:33110214 NCBI chrNW_004955543:452,172...484,564
Ensembl chrNW_004955543:452,121...484,560
JBrowse link
G Otud6a OTU deubiquitinase 6A enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955475:9,626,733...9,629,841 JBrowse link
G Otud6b OTU deubiquitinase 6B enables ISO (PMID:21267069) UniProt PMID:21267069 NCBI chrNW_004955417:7,844,311...7,859,032
Ensembl chrNW_004955417:7,844,292...7,858,658
JBrowse link
G Otud7a OTU deubiquitinase 7A enables ISO (PMID:23827681) UniProt PMID:23827681 NCBI chrNW_004955416:30,244,875...30,427,829 JBrowse link
G Otud7b OTU deubiquitinase 7B enables ISO (PMID:12682062)
(PMID:23827681), (PMID:28489822)
(PMID:23334419)
MGI
UniProt
PMID:12682062 PMID:23334419 PMID:23827681 PMID:28489822 NCBI chrNW_004955413:758,098...812,605
Ensembl chrNW_004955413:751,546...812,605
JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity enables ISO (PMID:23746843), (PMID:23806334), (PMID:23827681), (PMID:24726323), (PMID:24726327), (PMID:26997266), (PMID:27523608), (PMID:27559085)
(PMID:23708998), (PMID:27523608), (PMID:29950720)
(PMID:35170849), (PMID:35587511)
(PMID:26235645)
UniProt
Reactome
PMID:23708998 PMID:23746843 PMID:23806334 PMID:23827681 PMID:24726323 More... NCBI chrNW_004955426:3,953,852...3,982,532
Ensembl chrNW_004955426:3,953,933...3,982,175
JBrowse link
G Tank TRAF family member associated NFKB activator contributes_to ISO (PMID:25861989) UniProtKB PMID:25861989 NCBI chrNW_004955449:12,470,203...12,561,364
Ensembl chrNW_004955449:12,470,085...12,561,370
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 enables ISO (PMID:15258597), (PMID:23827681) UniProt PMID:15258597 PMID:23827681 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 enables ISO (PMID:9521656)
(PMID:12913066)
(PMID:34244144)
UniProt
MGI
FlyBase
PMID:9521656 PMID:12913066 PMID:34244144 NCBI chrNW_004955443:6,367,519...6,379,638
Ensembl chrNW_004955443:6,367,460...6,380,462
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 enables ISO (PMID:19047059), (PMID:9521656)
(PMID:26235645)
UniProt
Reactome
PMID:9521656 PMID:19047059 PMID:26235645 NCBI chrNW_004955404:31,414,076...31,465,205
Ensembl chrNW_004955404:31,414,208...31,464,968
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 enables ISO (PMID:28992318)
(PMID:18922472)
FlyBase
UniProt
PMID:18922472 PMID:28992318 NCBI chrNW_004955406:30,432,652...30,468,741 JBrowse link
G Usp1 ubiquitin specific peptidase 1 enables ISO (PMID:18082604)
(PMID:20129063)
UniProt PMID:18082604 PMID:20129063 NCBI chrNW_004955423:27,236,242...27,254,064
Ensembl chrNW_004955423:27,237,003...27,251,892
JBrowse link
G Usp10 ubiquitin specific peptidase 10 enables ISO (PMID:19398555), (PMID:25861989)
(PMID:20096447), (PMID:21962518), (PMID:31981475), (PMID:34348161), (PMID:34469731)
UniProt PMID:19398555 PMID:20096447 PMID:21962518 PMID:25861989 PMID:31981475 More... NCBI chrNW_004955541:242,182...296,018
Ensembl chrNW_004955541:242,091...296,059
JBrowse link
G Usp11 ubiquitin specific peptidase 11 enables ISO (PMID:15314155) UniProt PMID:15314155 NCBI chrNW_004955516:840,708...858,201
Ensembl chrNW_004955516:841,114...857,322
JBrowse link
G Usp12 ubiquitin specific peptidase 12 enables ISO (PMID:19075014) UniProt PMID:19075014 NCBI chrNW_004955497:6,524,487...6,613,403
Ensembl chrNW_004955497:6,524,487...6,556,675
JBrowse link
G Usp13 ubiquitin specific peptidase 13 enables ISO (PMID:21811243), (PMID:21962518), (PMID:22216260), (PMID:26280536) UniProt PMID:21811243 PMID:21962518 PMID:22216260 PMID:26280536 NCBI chrNW_004955420:8,835,858...8,919,837
Ensembl chrNW_004955420:8,835,549...8,919,933
JBrowse link
G Usp14 ubiquitin specific peptidase 14 enables ISO (PMID:19106094), (PMID:23958854) UniProt PMID:19106094 PMID:23958854 NCBI chrNW_004955402:9,710,080...9,737,601
Ensembl chrNW_004955402:9,710,080...9,743,077
JBrowse link
G Usp15 ubiquitin specific peptidase 15 enables ISO (PMID:12532266)
(PMID:16005295), (PMID:21947082), (PMID:22344298), (PMID:24526689), (PMID:27368102), (PMID:33093067)
PMID:10880343
RGD
MGI
UniProt
PMID:10880343 PMID:12532266 PMID:16005295 PMID:21947082 PMID:22344298 More... RGD:634484 NCBI chrNW_004955458:9,440,645...9,533,653
Ensembl chrNW_004955458:9,403,097...9,533,653
JBrowse link
G Usp16 ubiquitin specific peptidase 16 enables ISO (PMID:17914355), (PMID:32129764) UniProt PMID:17914355 PMID:32129764 NCBI chrNW_004955407:28,375,246...28,413,279 JBrowse link
G Usp19 ubiquitin specific peptidase 19 enables ISO (PMID:24356957)
(PMID:21971047)
(PMID:19465887)
ParkinsonsUK-UCL
UniProt
PMID:19465887 PMID:21971047 PMID:24356957 NCBI chrNW_004955532:1,104,212...1,115,267
Ensembl chrNW_004955532:1,104,591...1,113,567
JBrowse link
G Usp2 ubiquitin specific peptidase 2 enables ISO (PMID:17290220)
PMID:10938131
(PMID:19917254)
FlyBase
UniProt
PMID:10938131 PMID:17290220 PMID:19917254 RGD:634247 NCBI chrNW_004955412:20,435,778...20,461,898
Ensembl chrNW_004955412:20,433,302...20,457,493
JBrowse link
G Usp20 ubiquitin specific peptidase 20 enables ISO (PMID:19424180), (PMID:26839314), (PMID:29487085) UniProt PMID:19424180 PMID:26839314 PMID:29487085 NCBI chrNW_004955513:43,601...70,714
Ensembl chrNW_004955513:42,809...70,906
JBrowse link
G Usp21 ubiquitin specific peptidase 21 enables ISO (PMID:26100909)
(PMID:18172164)
(PMID:10799498), (PMID:32011234)
UniProt PMID:10799498 PMID:18172164 PMID:26100909 PMID:32011234 NCBI chrNW_004955468:12,923,121...12,929,780
Ensembl chrNW_004955468:12,924,574...12,929,497
JBrowse link
G Usp22 ubiquitin specific peptidase 22 contributes_to
enables
ISO (PMID:18206973)
(PMID:16378762)
(PMID:16378762), (PMID:32130408)
UniProtKB
MGI
UniProt
PMID:16378762 PMID:18206973 PMID:32130408 NCBI chrNW_004955577:979,317...1,002,478
Ensembl chrNW_004955577:978,152...1,002,480
JBrowse link
G Usp25 ubiquitin specific peptidase 25 enables ISO (PMID:18538659) UniProt PMID:18538659 NCBI chrNW_004955407:17,429,299...17,572,138
Ensembl chrNW_004955407:17,429,299...17,575,262
JBrowse link
G Usp27x ubiquitin specific peptidase 27 X-linked enables ISO (PMID:27013495) UniProt PMID:27013495 NCBI chrNW_004955543:1,023,931...1,027,048 JBrowse link
G Usp28 ubiquitin specific peptidase 28 enables ISO (PMID:16901786), (PMID:17558397) UniProt PMID:16901786 PMID:17558397 NCBI chrNW_004955412:15,425,136...15,469,819
Ensembl chrNW_004955412:15,426,159...15,443,023
JBrowse link
G Usp3 ubiquitin specific peptidase 3 enables ISO (PMID:17980597) UniProt PMID:17980597 NCBI chrNW_004955450:11,729,433...11,802,462
Ensembl chrNW_004955450:11,727,104...11,802,462
JBrowse link
G Usp30 ubiquitin specific peptidase 30 enables ISO (PMID:14715245), (PMID:24896179), (PMID:25621951)
(PMID:24513856)
UniProt PMID:14715245 PMID:24513856 PMID:24896179 PMID:25621951 NCBI chrNW_004955455:10,234,779...10,257,959
Ensembl chrNW_004955455:10,192,426...10,257,951
JBrowse link
G Usp31 ubiquitin specific peptidase 31 enables ISO (PMID:16214042) FlyBase PMID:16214042 NCBI chrNW_004955493:1,663,268...1,724,522
Ensembl chrNW_004955493:1,663,268...1,702,386
JBrowse link
G Usp32 ubiquitin specific peptidase 32 enables ISO (PMID:20549504), (PMID:36476874) UniProt PMID:20549504 PMID:36476874 NCBI chrNW_004955451:1,511,687...1,678,546 JBrowse link
G Usp33 ubiquitin specific peptidase 33 enables ISO (PMID:23486064)
(PMID:24056301)
UniProt PMID:23486064 PMID:24056301 NCBI chrNW_004955423:15,424,349...15,469,344
Ensembl chrNW_004955423:15,423,932...15,469,344
JBrowse link
G Usp34 ubiquitin specific peptidase 34 enables ISO (PMID:14715245), (PMID:21383061) UniProt PMID:14715245 PMID:21383061 NCBI chrNW_004955424:22,434,292...22,689,944
Ensembl chrNW_004955424:22,474,098...22,689,322
JBrowse link
G Usp35 ubiquitin specific peptidase 35 enables ISO (PMID:14715245) FlyBase PMID:14715245 NCBI chrNW_004955414:13,755,604...13,779,049
Ensembl chrNW_004955414:13,756,488...13,772,052
JBrowse link
G Usp36 ubiquitin specific peptidase 36 enables ISO (PMID:14715245) FlyBase PMID:14715245 NCBI chrNW_004955506:3,824,598...3,861,919
Ensembl chrNW_004955506:3,824,556...3,862,098
JBrowse link
G Usp37 ubiquitin specific peptidase 37 enables ISO (PMID:14715245), (PMID:21596315) FlyBase PMID:14715245 PMID:21596315 NCBI chrNW_004955453:14,846,044...14,931,336
Ensembl chrNW_004955453:14,846,044...14,931,336
JBrowse link
G Usp38 ubiquitin specific peptidase 38 enables ISO (PMID:14715245), (PMID:27692986) FlyBase PMID:14715245 PMID:27692986 NCBI chrNW_004955471:316,319...350,982
Ensembl chrNW_004955471:315,779...350,982
JBrowse link
G Usp39 ubiquitin specific peptidase 39 NOT|enables ISO (PMID:18728397) FlyBase PMID:18728397 NCBI chrNW_004955424:1,867,910...1,893,338
Ensembl chrNW_004955424:1,867,850...1,894,157
JBrowse link
G Usp4 ubiquitin specific peptidase 4 enables ISO (PMID:16316627), (PMID:16472766), (PMID:18728397), (PMID:30514904) UniProt PMID:16316627 PMID:16472766 PMID:18728397 PMID:30514904 NCBI chrNW_004955532:1,247,110...1,284,564
Ensembl chrNW_004955532:1,247,110...1,285,121
JBrowse link
G Usp44 ubiquitin specific peptidase 44 enables ISO (PMID:14715245), (PMID:17443180), (PMID:20402667)
(PMID:17443180), (PMID:20402667)
FlyBase
UniProt
PMID:14715245 PMID:17443180 PMID:20402667 NCBI chrNW_004955405:31,977,045...32,006,733
Ensembl chrNW_004955405:31,977,602...32,006,810
JBrowse link
G Usp45 ubiquitin specific peptidase 45 enables ISO (PMID:14715245)
(PMID:25538220), (PMID:30258100)
FlyBase
UniProt
PMID:14715245 PMID:25538220 PMID:30258100 NCBI chrNW_004955411:25,315,536...25,375,283
Ensembl chrNW_004955411:25,316,535...25,378,573
JBrowse link
G Usp46 ubiquitin specific peptidase 46 enables ISO (PMID:14715245), (PMID:19075014) FlyBase PMID:14715245 PMID:19075014 NCBI chrNW_004955447:17,915,451...17,975,149
Ensembl chrNW_004955447:17,900,611...17,971,601
JBrowse link
G Usp47 ubiquitin specific peptidase 47 enables ISO (PMID:21362556), (PMID:36749823) FlyBase PMID:21362556 PMID:36749823 NCBI chrNW_004955414:27,357,602...27,462,481
Ensembl chrNW_004955414:27,357,602...27,462,731
JBrowse link
G Usp49 ubiquitin specific peptidase 49 enables ISO (PMID:14715245), (PMID:23824326), (PMID:28363942) UniProt PMID:14715245 PMID:23824326 PMID:28363942 NCBI chrNW_004955437:8,187,118...8,237,910
Ensembl chrNW_004955437:8,191,236...8,198,809
JBrowse link
G Usp5 ubiquitin specific peptidase 5 enables ISO (PMID:24424410)
(PMID:26235645)
ParkinsonsUK-UCL
Reactome
PMID:24424410 PMID:26235645 NCBI chrNW_004955413:4,451,530...4,466,832
Ensembl chrNW_004955413:4,451,622...4,466,832
JBrowse link
G Usp50 ubiquitin specific peptidase 50 enables ISO (PMID:28094437), (PMID:36876523) UniProt PMID:28094437 PMID:36876523 NCBI chrNW_004955409:3,788,723...3,838,077
Ensembl chrNW_004955409:3,788,903...3,837,983
JBrowse link
G Usp53 ubiquitin specific peptidase 53 NOT|enables ISO (PMID:14715245) UniProt PMID:14715245 NCBI chrNW_004955428:20,957,807...21,023,380
Ensembl chrNW_004955428:20,957,807...21,023,380
JBrowse link
G Usp54 ubiquitin specific peptidase 54 enables ISO (PMID:36590171) UniProt PMID:36590171 NCBI chrNW_004955437:18,240,303...18,322,197
Ensembl chrNW_004955437:18,258,024...18,321,481
JBrowse link
G Usp7 ubiquitin specific peptidase 7 enables ISO (PMID:21268065)
(PMID:27863226)
(PMID:16964248), (PMID:21745816), (PMID:26280536), (PMID:28655758), (PMID:35216969)
(PMID:26235645)
(PMID:11923872), (PMID:26678539)
RGD
UniProt
Reactome
PMID:11923872 PMID:16328052 PMID:16964248 PMID:21268065 PMID:21745816 More... RGD:2316130 NCBI chrNW_004955442:9,316,022...9,355,751
Ensembl chrNW_004955442:9,315,225...9,356,393
JBrowse link
G Usp8 ubiquitin specific peptidase 8 enables ISO (PMID:16520378), (PMID:18388320), (PMID:18728397), (PMID:27444016)
(PMID:11500497), (PMID:15342353), (PMID:16120644), (PMID:16771824)
MGI
UniProt
PMID:11500497 PMID:15342353 PMID:16120644 PMID:16520378 PMID:16771824 More... NCBI chrNW_004955409:3,839,308...3,903,595
Ensembl chrNW_004955409:3,840,007...3,891,284
JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked enables ISO (PMID:22371489), (PMID:26235645)
(PMID:12895410)
Reactome
UniProt
PMID:12895410 PMID:22371489 PMID:26235645 NCBI chrNW_004955565:1,479,040...1,602,070
Ensembl chrNW_004955565:1,479,040...1,602,070
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 enables ISO PMID:15037600
(PMID:23827681), (PMID:32649882)
RGD
UniProt
PMID:15037600 PMID:23827681 PMID:32649882 RGD:1302353 NCBI chrNW_004955444:12,542,479...12,567,971
Ensembl chrNW_004955444:12,542,479...12,567,971
JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A contributes_to ISO (PMID:25861989) UniProtKB PMID:25861989 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959
JBrowse link
G Zranb1 zinc finger RANBP2-type containing 1 enables ISO (PMID:18281465)
(PMID:18281465), (PMID:23827681), (PMID:25752573), (PMID:25752577)
UniProt PMID:18281465 PMID:23827681 PMID:25752573 PMID:25752577 NCBI chrNW_004955477:2,864,737...2,922,069
Ensembl chrNW_004955477:2,873,170...2,922,069
JBrowse link
Met1-linked polyubiquitin deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase enables ISO (PMID:26997266) Reactome PMID:26997266 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14359
    catalytic activity 3751
      hydrolase activity 1337
        peptidase activity 355
          cysteine-type peptidase activity 110
            cysteine-type deubiquitinase activity 67
              Met1-linked polyubiquitin deubiquitinase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 14359
    catalytic activity 3751
      hydrolase activity 1337
        peptidase activity 355
          ubiquitin-like protein peptidase activity 90
            deubiquitinase activity 78
              cysteine-type deubiquitinase activity 67
                Met1-linked polyubiquitin deubiquitinase activity 1
paths to the root