Usp19 (ubiquitin specific peptidase 19) - Rat Genome Database

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Gene: Usp19 (ubiquitin specific peptidase 19) Chinchilla lanigera
Analyze
Symbol: Usp19
Name: ubiquitin specific peptidase 19
RGD ID: 8709808
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); Hsp90 protein binding (ortholog); K48-linked deubiquitinase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); negative regulation of proteasomal protein catabolic process (ortholog); negative regulation of skeletal muscle tissue development (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 1 (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2P (ortholog); carnitine-acylcarnitine translocase deficiency (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 19
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,104,591 - 1,113,567 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,104,212 - 1,115,267 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Usp19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,104,591 - 1,113,567 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,104,212 - 1,115,267 (-)NCBIChiLan1.0ChiLan1.0
USP19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,108,050 - 49,120,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl349,108,046 - 49,120,938 (-)EnsemblGRCh38hg38GRCh38
GRCh37349,145,483 - 49,158,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,121,112 - 49,133,217 (-)NCBINCBI36Build 36hg18NCBI36
Build 34349,121,111 - 49,133,217NCBI
Celera349,103,060 - 49,115,165 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef349,204,015 - 49,216,907 (-)NCBIHuRef
CHM1_1349,098,226 - 49,111,118 (-)NCBICHM1_1
T2T-CHM13v2.0349,136,122 - 49,148,895 (-)NCBIT2T-CHM13v2.0
Usp19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,367,806 - 108,379,536 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,367,801 - 108,379,536 (+)EnsemblGRCm39 Ensembl
GRCm389108,490,607 - 108,502,337 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,490,602 - 108,502,337 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,393,007 - 108,404,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,348,851 - 108,359,802 (+)NCBIMGSCv36mm8
Celera9108,100,140 - 108,111,769 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.42NCBI
Usp19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,069,227 - 118,080,283 (+)NCBIGRCr8
mRatBN7.28109,190,727 - 109,201,761 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,190,724 - 109,201,741 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,810,756 - 114,819,397 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,010,088 - 113,018,729 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,852,728 - 110,861,369 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,280,690 - 117,291,729 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,280,705 - 117,291,351 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,625,419 - 116,636,432 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,488,932 - 108,497,573 (+)ENTREZGENECelera
Cytogenetic Map8q32NCBI
USP19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2249,086,568 - 49,099,415 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1349,091,336 - 49,104,185 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0349,032,373 - 49,045,238 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1350,112,271 - 50,125,114 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,100,216 - 50,125,112 (-)Ensemblpanpan1.1panPan2
USP19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,062,802 - 40,074,221 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,064,599 - 40,074,082 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2039,980,975 - 39,992,470 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,419,685 - 40,431,184 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,419,711 - 40,431,178 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,786,538 - 39,798,032 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,190,048 - 40,201,538 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,470,345 - 40,481,844 (+)NCBIUU_Cfam_GSD_1.0
Usp19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,054,119 - 64,065,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529813,951 - 826,014 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529814,649 - 826,008 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,726,672 - 31,737,981 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,726,668 - 31,738,135 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,958,907 - 34,968,638 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,510,554 - 10,523,576 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,510,423 - 10,523,487 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041156,558,381 - 156,571,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,133,595 - 3,146,221 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247303,134,419 - 3,145,512 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000013858   ⟹   ENSCLAP00000013703
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555321,104,591 - 1,113,567 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000013859   ⟹   ENSCLAP00000013704
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555321,104,591 - 1,113,567 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000013860   ⟹   ENSCLAP00000013705
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555321,105,135 - 1,113,567 (-)Ensembl
RefSeq Acc Id: XM_005410189   ⟹   XP_005410246
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555321,104,852 - 1,115,267 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005410190   ⟹   XP_005410247
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555321,104,212 - 1,115,265 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005410191   ⟹   XP_005410248
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555321,104,212 - 1,115,266 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013507630   ⟹   XP_013363084
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555321,104,852 - 1,115,267 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005410248   ⟸   XM_005410191
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VCW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005410247   ⟸   XM_005410190
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VCW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005410246   ⟸   XM_005410189
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YPH1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363084   ⟸   XM_013507630
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YPH1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000013704   ⟸   ENSCLAT00000013859
Ensembl Acc Id: ENSCLAP00000013703   ⟸   ENSCLAT00000013858
Ensembl Acc Id: ENSCLAP00000013705   ⟸   ENSCLAT00000013860
Protein Domains
CS   MYND-type   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009469 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013858 ENTREZGENE
  ENSCLAT00000013858.1 UniProtKB/TrEMBL
  ENSCLAT00000013859 ENTREZGENE
  ENSCLAT00000013859.1 UniProtKB/TrEMBL
  ENSCLAT00000013860 ENTREZGENE
  ENSCLAT00000013860.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro CS_dom UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
NCBI Gene Usp19 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 UniProtKB/TrEMBL
Pfam PF04969 UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  USP19_linker UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PROSITE PS51203 UniProtKB/TrEMBL
  USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/TrEMBL
  SSF49764 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A8C2VCT9_CHILA UniProtKB/TrEMBL
  A0A8C2VCW6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YPH1 ENTREZGENE, UniProtKB/TrEMBL