Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:oligospermia
go back to main search page
Accession:DOID:14228 term browser browse the term
Definition:A male fertility issue defined as a low sperm concentration in the ejaculate. (DO)
Synonyms:exact_synonym: Low Sperm Count;   hypospermatogeneses;   hypospermatogenesis;   low sperm counts;   oligozoospermia
 primary_id: MESH:D009845
 xref: ICD10CM:N46.1;   ICD9CM:606.1;   NCI:C34860
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
oligospermia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCKDK branched chain keto acid dehydrogenase kinase ISO DNA:missense mutation:cds:G369E (rat) RGD PMID:27472223 RGD:39131293 NCBI chr 6:17,128,615...17,132,925
Ensembl chr 6:17,128,824...17,133,585 		JBrowse link
G BRDT bromodomain testis associated susceptibility ISO DNA:SNP: :rs3088232(human) RGD PMID:22016351 RGD:9586360 NCBI chr 6:56,918,939...56,977,355
Ensembl chr 6:56,919,195...56,965,638 		JBrowse link
G BRWD1 bromodomain and WD repeat domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18353305 NCBI chr31:34,122,477...34,240,555
Ensembl chr31:34,122,463...34,240,639 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26181198 NCBI chr18:53,958,380...53,971,120
Ensembl chr18:53,958,475...53,971,119 		JBrowse link
G CDC14A cell division cycle 14A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29293958 NCBI chr 6:49,429,675...49,678,376
Ensembl chr 6:49,497,939...49,693,665 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide ISO CTD Direct Evidence: therapeutic CTD PMID:16483355 NCBI chr12:46,610,801...46,629,322
Ensembl chr12:46,610,973...46,636,640 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO CTD Direct Evidence: marker/mechanism CTD PMID:22381205 NCBI chr 8:63,970,245...64,029,438
Ensembl chr 8:63,972,027...64,019,879 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20833731 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544 		JBrowse link
G FAM83F family with sequence similarity 83 member F ISO ClinVar Annotator: match by term: Oligozoospermia ClinVar PMID:25741868 NCBI chr10:25,106,663...25,140,989
Ensembl chr10:25,108,003...25,140,989 		JBrowse link
G FSHB follicle stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:4607150 NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680 		JBrowse link
G KIF3B kinesin family member 3B ISO ClinVar Annotator: match by term: Oligospermia ClinVar NCBI chr24:21,661,730...21,706,839
Ensembl chr24:21,661,059...21,802,815 		JBrowse link
G LOC486307 piwi-like protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20940137 NCBI chr26:17,035,530...17,063,177
Ensembl chr26:17,036,963...17,061,992 		JBrowse link
G MSH4 mutS homolog 4 ISO ClinVar Annotator: match by term: Oligospermia ClinVar PMID:25741868 PMID:33448284 NCBI chr 6:70,745,777...70,822,507
Ensembl chr 6:70,746,634...70,823,004 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29983398 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23384712 NCBI chr  X:25,396,527...25,401,587
Ensembl chr  X:25,396,527...25,401,715 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20940137 NCBI chr21:6,319,986...6,391,149
Ensembl chr21:6,319,987...6,366,787 		JBrowse link
G PNLDC1 PARN like ribonuclease domain containing exonuclease 1 ISO ClinVar Annotator: match by term: Oligospermia ClinVar PMID:25741868 NCBI chr 1:49,045,153...49,063,008
Ensembl chr 1:49,044,979...49,062,802 		JBrowse link
G TBC1D25 TBC1 domain family member 25 ISO ClinVar Annotator: match by term: Oligospermia ClinVar NCBI chr  X:41,782,774...41,799,083
Ensembl chr  X:41,782,671...41,798,828 		JBrowse link
G TPCN1 two pore segment channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24451262 NCBI chr26:10,599,898...10,662,269
Ensembl chr26:10,599,780...10,660,767 		JBrowse link
G YTHDC2 YTH N6-methyladenosine RNA binding protein C2 ISO CTD Direct Evidence: therapeutic CTD PMID:34822792 NCBI chr11:3,537,571...3,613,455
Ensembl chr11:3,536,854...3,612,282 		JBrowse link
CRYPTOZOOSPERMIA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G M1AP meiosis 1 associated protein ISO ClinVar Annotator: match by term: Cryptozoospermia ClinVar PMID:25741868 PMID:32673564 NCBI chr17:48,510,569...48,588,589
Ensembl chr17:48,510,094...48,587,547 		JBrowse link
G SYCP2 synaptonemal complex protein 2 ISO ClinVar Annotator: match by term: Cryptozoospermia ClinVar PMID:25741868 PMID:31866047 NCBI chr24:44,471,516...44,546,501
Ensembl chr24:44,471,828...44,546,495 		JBrowse link
G TRIM71 tripartite motif containing 71 ISO ClinVar Annotator: match by term: Cryptozoospermia ClinVar PMID:25741868 NCBI chr23:3,888,287...3,959,910
Ensembl chr23:3,893,647...3,960,411 		JBrowse link
hypogonadotropic hypogonadism 24 without anosmia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHB follicle stimulating hormone subunit beta ISO ClinVar Annotator: match by term: Hypogonadotropic hypogonadism 24 without anosmia OMIM
ClinVar		 PMID:4344039 PMID:8220432 PMID:9271483 PMID:9280841 PMID:9624193 More... NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680 		JBrowse link
oligoasthenoteratozoospermia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGFG1 ArfGAP with FG repeats 1 ISO MouseDO NCBI chr25:40,229,732...40,307,277
Ensembl chr25:40,243,734...40,301,135 		JBrowse link
G CCDC157 coiled-coil domain containing 157 ISO MouseDO NCBI chr26:23,504,167...23,520,311
Ensembl chr26:23,504,882...23,518,927 		JBrowse link
G CFAP58 cilia and flagella associated protein 58 ISO MouseDO NCBI chr28:16,653,212...16,752,229
Ensembl chr28:16,653,208...16,751,838 		JBrowse link
G CFAP61 cilia and flagella associated protein 61 ISO MouseDO NCBI chr24:3,018,791...3,294,646
Ensembl chr24:3,018,781...3,287,597 		JBrowse link
G CFAP70 cilia and flagella associated protein 70 ISO MouseDO NCBI chr 4:23,830,335...23,926,922
Ensembl chr 4:23,830,336...23,924,350 		JBrowse link
G MLX MAX dimerization protein MLX ISO MouseDO NCBI chr 9:20,391,762...20,395,792
Ensembl chr 9:20,391,762...20,395,735 		JBrowse link
G POC1B POC1 centriolar protein B ISO MouseDO NCBI chr15:30,388,351...30,481,294
Ensembl chr15:30,382,033...30,483,135 		JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit ISO MouseDO NCBI chr 6:18,085,048...18,092,861
Ensembl chr 6:18,085,116...18,092,854 		JBrowse link
G SPATA20 spermatogenesis associated 20 ISO MouseDO NCBI chr 9:26,468,931...26,476,218
Ensembl chr 9:26,468,208...26,476,211 		JBrowse link
Young Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 ISO ClinVar Annotator: match by term: Male infertility due to obstructive azoospermia ClinVar NCBI chr  X:60,374,743...60,396,244
Ensembl chr  X:60,374,754...60,423,947 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17773
    disease of anatomical entity 15151
      reproductive system disease 2898
        male reproductive system disease 1901
          male infertility 255
            oligospermia 33
              CRYPTOZOOSPERMIA 3
              Young Syndrome 1
              hypogonadotropic hypogonadism 24 without anosmia 1
              oligoasthenoteratozoospermia 9
Path 2
Term Annotations click to browse term
  disease 17773
    disease of anatomical entity 15151
      Urogenital Diseases 4737
        Female Urogenital Diseases and Pregnancy Complications 2356
          Female Urogenital Diseases 1916
            female reproductive system disease 1913
              infertility 330
                male infertility 255
                  oligospermia 33
                    CRYPTOZOOSPERMIA 3
                    Young Syndrome 1
                    hypogonadotropic hypogonadism 24 without anosmia 1
                    oligoasthenoteratozoospermia 9
paths to the root