LOC486307 (piwi-like protein 1) - Rat Genome Database

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Gene: LOC486307 (piwi-like protein 1) Canis lupus familiaris
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Symbol: LOC486307 (Ensembl: PIWIL3)
Name: piwi-like protein 1
RGD ID: 12221871
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); piRNA binding (inferred); RNA binding (inferred); INVOLVED IN regulation of translation (inferred); regulatory ncRNA-mediated gene silencing (inferred); ASSOCIATED WITH genetic disease (ortholog); oligospermia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: piwi-like 3; piwi-like protein 3; PIWIL3
RGD Orthologs
Human
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,035,530 - 17,063,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,036,963 - 17,061,992 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,739,185 - 18,766,762 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02617,379,223 - 17,407,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2617,380,903 - 17,406,205 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,948,385 - 18,974,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,369,622 - 17,397,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,387,029 - 17,414,680 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)
P granule  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC486307
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,035,530 - 17,063,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,036,963 - 17,061,992 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,739,185 - 18,766,762 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02617,379,223 - 17,407,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2617,380,903 - 17,406,205 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,948,385 - 18,974,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,369,622 - 17,397,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,387,029 - 17,414,680 (-)NCBIUU_Cfam_GSD_1.0
PIWIL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,719,034 - 24,774,720 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,719,034 - 24,774,720 (-)EnsemblGRCh38hg38GRCh38
GRCh372225,115,001 - 25,170,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,445,001 - 23,500,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 342223,439,554 - 23,495,237NCBI
Celera228,919,401 - 8,975,139 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef228,063,447 - 8,119,140 (-)NCBIHuRef
CHM1_12225,073,992 - 25,129,703 (-)NCBICHM1_1
T2T-CHM13v2.02225,180,480 - 25,236,180 (-)NCBIT2T-CHM13v2.0
PIWIL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,622,587 - 34,705,478 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,320,755 - 37,403,651 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,678,784 - 5,721,948 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,347,633 - 23,390,380 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensemblpanpan1.1panPan2
PIWIL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,835,302 - 42,869,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11442,834,819 - 42,869,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21445,566,922 - 45,600,516 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIWIL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,826,068 - 7,866,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl197,826,757 - 7,865,934 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045118,012,577 - 118,068,691 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Piwil3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474712,587,798 - 12,629,494 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC486307
591 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 8
Below cutoff 2 11 1 6 1 5 1 7 8 2

Sequence


RefSeq Acc Id: ENSCAFT00000016829   ⟹   ENSCAFP00000015573
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2617,036,963 - 17,061,992 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000076767   ⟹   ENSCAFP00000051580
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2617,036,963 - 17,055,664 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036115   ⟹   ENSCAFP00845028263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2617,380,903 - 17,406,205 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036273   ⟹   ENSCAFP00845028385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2617,380,903 - 17,399,877 (-)Ensembl
RefSeq Acc Id: XM_038436166   ⟹   XP_038292094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02617,379,223 - 17,407,390 (-)NCBI
RefSeq Acc Id: XM_038459211   ⟹   XP_038315139
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2618,739,185 - 18,766,762 (+)NCBI
RefSeq Acc Id: XM_038512597   ⟹   XP_038368525
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12618,948,385 - 18,974,803 (+)NCBI
RefSeq Acc Id: XM_038576091   ⟹   XP_038432019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02617,387,029 - 17,414,680 (-)NCBI
RefSeq Acc Id: XM_038638762   ⟹   XP_038494690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02617,369,622 - 17,397,271 (-)NCBI
RefSeq Acc Id: ENSCAFP00000051580   ⟸   ENSCAFT00000076767
RefSeq Acc Id: ENSCAFP00000015573   ⟸   ENSCAFT00000016829
RefSeq Acc Id: XP_038368525   ⟸   XM_038512597
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038494690   ⟸   XM_038638762
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038292094   ⟸   XM_038436166
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TW56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315139   ⟸   XM_038459211
- Peptide Label: isoform X5
- UniProtKB: A0A8C0TSJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432019   ⟸   XM_038576091
- Peptide Label: isoform X4
- UniProtKB: A0A8C0TW56 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028263   ⟸   ENSCAFT00845036115
RefSeq Acc Id: ENSCAFP00845028385   ⟸   ENSCAFT00845036273
Protein Domains
PAZ   Piwi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010566 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040024342 UniProtKB/TrEMBL
  ENSCAFG00845020348 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016829.5 UniProtKB/TrEMBL
  ENSCAFT00000076767.2 UniProtKB/TrEMBL
  ENSCAFT00040046549.1 UniProtKB/TrEMBL
  ENSCAFT00040046586.1 UniProtKB/TrEMBL
  ENSCAFT00845036115 ENTREZGENE
  ENSCAFT00845036115.1 UniProtKB/TrEMBL
  ENSCAFT00845036273.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
  paz domain UniProtKB/TrEMBL
InterPro PAZ_dom UniProtKB/TrEMBL
  PAZ_dom_sf UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
NCBI Gene LOC486307 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2C UniProtKB/TrEMBL
  PIWI-LIKE PROTEIN 3 UniProtKB/TrEMBL
Pfam PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
PROSITE PAZ UniProtKB/TrEMBL
  PIWI UniProtKB/TrEMBL
SMART PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
Superfamily-SCOP SSF101690 UniProtKB/TrEMBL
  SSF53098 UniProtKB/TrEMBL
UniProt A0A8C0TSJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TW56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PCG3_CANLF UniProtKB/TrEMBL
  A0A8I3PKB7_CANLF UniProtKB/TrEMBL
  A0A8P0NCM2_CANLF UniProtKB/TrEMBL
  A0A8P0T457_CANLF UniProtKB/TrEMBL