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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:trichinosis
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Accession:DOID:9784 term browser browse the term
Definition:A parasitic helminthiasis infectious disease that involves parasitic infection of animals and humans by Trichinella spiralis, Trichinella nativa or Trichinella britovi. Intestinal invasion causes diarrhea, abdominal pain and vomiting. Larval migration into muscle tissues can cause periorbital and facial edema, conjunctivitis, fever, myalgias, splinter hemorrhages, rashes, and blood eosinophilia. Myocarditis, central nervous system involvement, and pneumonitis can also occur. (DO)
Synonyms:exact_synonym: Human Trichinellosis;   Trichinelliases;   Trichinelliasis;   Trichinelloses;   human trichinelloses;   trichinella spiralis infection;   trichinellosis;   trichinoses
 primary_id: MESH:D014235
 xref: EFO:0007520;   ICD10CM:B75;   ICD9CM:124;   NCI:C85199


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trichinosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO RGD PMID:23465441 RGD:11049476 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:19564380 RGD:8548805 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP protein:increased expression:dorsal horn of spinal cord, dorsal root ganglion RGD PMID:22160634 RGD:9999169 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO protein:decreased expression:jejunum (mouse) RGD PMID:16336502 RGD:38676482 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:19564380 RGD:8548805 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression ISO RGD PMID:23024277 RGD:38596337 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19057
    disease by infectious agent 2250
      parasitic infectious disease 327
        parasitic helminthiasis infectious disease 83
          Nematode Infections 38
            Adenophorea Infections 8
              Enoplida Infections 8
                trichinosis 6
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