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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:parasitic helminthiasis infectious disease
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Accession:DOID:883 term browser browse the term
Definition:A parasitic infectious disease that occurs when part of the body is infested with parasitic worms such as cestodes, nematodes and trematodes. (DO)
Synonyms:exact_synonym: helminth infection;   helminthiases;   helminthiasis;   helminthosis;   nematomorpha infection;   nematomorpha infections;   worm infection
 primary_id: MESH:D006373
 xref: EFO:1001342;   ICD10CM:B83.9;   ICD9CM:120-129.99;   NCI:C84751
For additional species annotation, visit the Alliance of Genome Resources.


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parasitic helminthiasis infectious disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2rb interleukin 2 receptor subunit beta ameliorates ISO RGD PMID:21301182 RGD:42724469 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il33 interleukin 33 treatment ISO RGD PMID:25912172 RGD:39939026 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Mir146a microRNA 146a exacerbates ISO RGD PMID:25024218 RGD:126925154 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
alveolar echinococcosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule treatment ISO RGD PMID:30315719 RGD:41410787 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G RT1-Bb RT1 class II, locus Bb disease_progression ISO DNA:polymorphism: :HLA-DQB1*02(human) RGD PMID:9756400 RGD:36174003 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO DNA:polymorphisms: :HLA-DRB1*03, DRB1*11(human) RGD PMID:9756400 RGD:36174003 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA:increased expression:PBMC RGD PMID:30141853 RGD:15090814 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
angiostrongyliasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl1 interleukin 1 receptor-like 1 treatment ISO mRNA:increased expression:brain: RGD PMID:24657070 PMID:23148283 RGD:11561855, RGD:40400713 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 ISO protein:increased expression:brain: RGD PMID:23148283 PMID:24076431 RGD:40400713, RGD:40400715 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il5 interleukin 5 ISO RGD PMID:8361777 RGD:11354948 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Mag myelin-associated glycoprotein disease_progression ISO RGD PMID:20399564 RGD:27226693 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mbp myelin basic protein disease_progression ISO RGD PMID:20399564 RGD:27226693 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein disease_progression ISO RGD PMID:20399564 RGD:27226693 NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563 		JBrowse link
Animal Helminthiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule ISO protein:increased expression:plasmacytoid dendritic cell RGD PMID:20702728 RGD:5490530 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
Cestode Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc2 mucin 2, oligomeric mucus/gel-forming IEP RGD PMID:17187651 RGD:7349350 NCBI chr 1:196,796,257...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
clonorchiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:liver, serum:
protein:increased expression:serum:		 RGD PMID:26944417 PMID:26944417 RGD:39939001, RGD:39939001 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28784165 RGD:15090810 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
cystic echinococcosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 treatment ISO RGD PMID:25726962 RGD:14696685 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO DNA:polymorphisms: :HLA- DQB1*0.9, DQB1*02(human) RGD PMID:22308705 RGD:36174019 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO DNA:polymorphism: :HLA-DRB1*03, DRB1*07(human) RGD PMID:22308705 RGD:36174019 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Tlr2 toll-like receptor 2 disease_progression ISO DNA:mutation:cds:Arg753Gln(human)
mRNA:increased expression:peripheral blood monocyte:		 RGD PMID:31437685 PMID:21923667 RGD:15090825, RGD:18182935 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA:increased expression:peripheral blood monocyte: RGD PMID:21923667 RGD:18182935 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
echinococcosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO RGD PMID:2142987 RGD:5128834 NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:24270252 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Hbb hemoglobin subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24270252 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Il5 interleukin 5 ISO mRNA: increased expression: : peritoneal lavage cells RGD PMID:21912714 RGD:5687176 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:24270252 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
fascioliasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsb cathepsin B IEP protein:decreased activity:liver (rat) RGD PMID:19696938 RGD:2315504 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:increased expression:serum RGD PMID:10431747 RGD:6484593 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
filariasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl1 interleukin 1 receptor-like 1 ISO RGD PMID:27592711 RGD:40400889 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein ISO RGD PMID:24626328 RGD:40903014 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
Hepatic Echinococcosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule ISO mRNA, protein:increased expression:liver RGD PMID:25907244 RGD:41412175 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Igf2 insulin-like growth factor 2 ISO protein:decreased expression:serum RGD PMID:12927688 RGD:5509967 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Pdcd1 programmed cell death 1 ISO mRNA, protein:increased expression:liver RGD PMID:25907244 RGD:41412175 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
hepatosplenic schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd209a CD209a molecule ISO mRNA,protein:decreased expression:spleen,liver (mouse) RGD PMID:29386115 PMID:24729611 RGD:39938990, RGD:39938995 NCBI chr12:1,822,663...1,828,246
Ensembl chr12:1,822,663...1,828,246 		JBrowse link
G Clec4m C-type lectin domain family 4 member M ISO RGD PMID:18981244 RGD:39938988 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539 		JBrowse link
G Krt18 keratin 18 disease_progression ISO protein:increased expression:serum (mouse, human) RGD PMID:21357724 RGD:21406434 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:liver, hepatic stellate cell (mouse)
miRNA:increased expression:liver (mouse)
miRNA:increased expression:liver, macrophage (mouse)		 RGD PMID:25116007 PMID:25051829 PMID:27780686 RGD:126925174, RGD:126925180, RGD:126925179 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Serpinf1 serpin family F member 1 ISO RGD PMID:9038736 RGD:30296660 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
Hookworm Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl1 interleukin 1 receptor-like 1 ISO RGD PMID:22329990 RGD:39938827 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:Bronchoalveolar lavage, epithelium, macrophage RGD PMID:22329990 RGD:39938827 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Tff2 trefoil factor 2 ISO RGD PMID:22329990 RGD:39938827 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
Intestinal Helminthiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO RGD PMID:29950724 RGD:14974257 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 disease_progression ISO RGD PMID:12370384 RGD:40902988 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 treatment ISO RGD PMID:12370384 RGD:40902988 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
Nematode Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP protein:increased expression:liver (rat) RGD PMID:12621079 RGD:2306675 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:27697499 RGD:40400689 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 ISO associated with Nippostrongylus brasiliensis infection; mRNA:increased expression:lung RGD PMID:22331917 RGD:40400742 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 IEP mRNA:increased expression:spleen RGD PMID:17570971 RGD:2317296 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Muc13 mucin 13, cell surface associated ISO protein:increased expression:cecum, glycocalyx RGD PMID:21155842 RGD:7364766 NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming IEP
ISO		 mRNA:increased expression:intestine RGD PMID:16689826 PMID:20138044 RGD:2303607, RGD:7349349 NCBI chr 1:196,796,257...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Muc3 mucin 3 IEP mRNA:increased expression:intestine RGD PMID:16689826 RGD:2303607 NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522 		JBrowse link
G Muc4 mucin 4, cell surface associated IEP
ISO		 mRNA:increased expression:intestine
protein:increased expression:cecum, glycocalyx		 RGD PMID:16689826 PMID:21155842 RGD:2303607, RGD:7364766 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming resistance ISO
IEP		 mRNA:increased expression:cecum RGD PMID:20138044 PMID:22269441 RGD:7349349, RGD:7364747 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 susceptibility ISO RGD PMID:11850627 RGD:737789 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP mRNA:increased expression:liver (rat) RGD PMID:20695884 RGD:5130965 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
Ocular Onchocerciasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:19168746 RGD:8662882 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:11884755 RGD:7794682 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
onchocerciasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 severity ISO protein:increased expression:serum RGD PMID:22805723 RGD:8549600 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphisms: :HLA-DQA1*0401, HLA-DQA1*0102,HLA-DQA1*0103; RGD PMID:22117902 RGD:8547660 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Ha RT1 class II, locus Ha ISO RGD PMID:8854084 RGD:6480649 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
opisthorchiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 ISO RGD PMID:25809205 RGD:11570559 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Mir192 microRNA 192 ISO RNA:increased expression:urine RGD PMID:26456596 RGD:41404678 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:lung (mouse) RGD PMID:23369670 RGD:7243187 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Bud31 BUD31 homolog IEP Protein:increased expression:serum (human) RGD PMID:22686541 RGD:10058982 NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:liver RGD PMID:29554131 RGD:39938854 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Mir146a microRNA 146a disease_progression ISO miRNA:altered expression: blood serum (mouse) RGD PMID:32443549 RGD:126925171 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19041905 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23527093 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 treatment ISO DNA:polymorphism: :HLA-DRB1*13 RGD PMID:16709874 RGD:36049813 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO RGD PMID:32404867 RGD:39128195 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23527093 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
Schistosomiasis Japonica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule treatment ISO RGD PMID:33283278 RGD:127345110 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:19467215 RGD:14696662 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO protein:increased expression:serum RGD PMID:22590860 PMID:25944738 PMID:25944738 RGD:39939027, RGD:40400890, RGD:40400890 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Mir223 microRNA 223 treatment ISO RNA:increased expression:plasma: RGD PMID:24330517 PMID:24330517 RGD:21408589, RGD:21408589 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Pdcd1 programmed cell death 1 severity ISO protein:increased expression:CD4 T cell RGD PMID:27792733 PMID:27792733 PMID:27792733 RGD:40818413, RGD:40818413, RGD:40818413 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphisms: : RGD PMID:16042197 RGD:14398841 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G Serpinh1 serpin family H member 1 ISO mRNA,protein:increased expression:liver, serum (mouse) RGD PMID:31612672 RGD:41412161 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
Schistosomiasis Mansoni term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 ISO mRNA:increased expression:macrophage RGD PMID:22927819 RGD:14367882 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:10623823 RGD:11520789 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd86 CD86 molecule ISO protein:increased expression:peripheral blood, eosinophil (human) RGD PMID:17308795 RGD:11354987 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Ihh Indian hedgehog signaling molecule ISO RGD PMID:23121638 RGD:12910981 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Il13 interleukin 13 treatment IMP RGD PMID:10903803 RGD:8549615 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:27487182 RGD:151356963 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:9673227 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16564582 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19797157 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ISO RGD PMID:21332515 RGD:126925988 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Tslp thymic stromal lymphopoietin treatment ISO RGD PMID:22882457 RGD:38596354 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
Strongylida Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO RGD PMID:23630966 RGD:32716404 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Il3 interleukin 3 ISO RGD PMID:20500666 RGD:5686890 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il33 interleukin 33 ISO mRNA:increased expression:lung RGD PMID:22331917 RGD:40400742 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Plau plasminogen activator, urokinase IMP RGD PMID:18022622 RGD:6484141 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
strongyloidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 treatment ISO RGD PMID:16129701 RGD:8655932 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il5 interleukin 5 severity ISO RGD PMID:9824515 RGD:11354934 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
toxascariasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tslp thymic stromal lymphopoietin ISO mRNA:increased expression:multiple (mouse) RGD PMID:24327787 RGD:38596353 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
Toxocara Canis Infection (Canine Roundworms) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 ISO protein:increased expression:plasma, respiratory system fluid/secretion RGD PMID:16168564 RGD:7248410 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
toxocariasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 treatment ISO RGD PMID:26732352 RGD:11534298 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 ISO RGD PMID:25773181 RGD:40902825 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
trichinosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO RGD PMID:23465441 RGD:11049476 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:19564380 RGD:8548805 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP protein:increased expression:dorsal horn of spinal cord, dorsal root ganglion RGD PMID:22160634 RGD:9999169 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO protein:decreased expression:jejunum (mouse) RGD PMID:16336502 RGD:38676482 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:19564380 RGD:8548805 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression ISO RGD PMID:23024277 RGD:38596337 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
trichostrongyloidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 IEP mRNA:increased expression:duodenum (rat) RGD PMID:21698235 RGD:11561920 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
trichuriasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:20864659 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20864659 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Tslp thymic stromal lymphopoietin susceptibility ISO RGD PMID:19273626 RGD:38549593 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
urinary schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule ISO protein:increased expression:B cell (human) RGD PMID:22347409 RGD:127345101 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNPs:multiple:Gabonese(human) RGD PMID:22288822 RGD:7204674 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Il5 interleukin 5 resistance ISO RGD PMID:9697734 RGD:7241010 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO DNA:SNP:enhancer: (rs324013) RGD PMID:18273035 RGD:7243977 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18246
    disease by infectious agent 2145
      parasitic infectious disease 322
        parasitic helminthiasis infectious disease 83
          Animal Helminthiasis + 4
          Central Nervous System Helminthiasis + 7
          Cestode Infections + 14
          Intestinal Helminthiasis + 10
          Nematode Infections + 38
          Trematode Infections + 41
          ascaridiasis 0
          clonorchiasis 4
          diphyllobothriasis + 0
          dracunculiasis + 0
          echinococcosis + 13
          echinostomiasis 0
          fascioloidiasis 0
          fasciolopsiasis + 41
          hymenolepiasis 0
          metagonimiasis 0
          necatoriasis 0
          toxascariasis 1
          trichostrongyloidiasis + 1
paths to the root