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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Dental Pulp Exposure
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Accession:DOID:9000930 term browser browse the term
Definition:The result of pathological changes in the hard tissue of a tooth caused by carious lesions, mechanical factors, or trauma, which render the pulp susceptible to bacterial invasion from the external environment.
Synonyms:primary_id: MESH:D003789
 xref: EFO:1001782


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Dental Pulp Exposure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule IEP mRNA:increased expression:thalamus (rat)
mRNA:increased expression:periodontal ligament (rat)		 RGD PMID:20171363 PMID:20113783 RGD:4892246, RGD:4892210 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP protein:increased expression:neuron: RGD PMID:17645513 RGD:9686147 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP protein:increased expression:neuron: RGD PMID:17645513 RGD:9686147 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 IEP protein:increased expression:neuron: RGD PMID:17645513 RGD:9686147 NCBI chr 2:174,551,861...174,567,459
Ensembl chr 2:174,551,680...174,565,966 		JBrowse link
G Optn optineurin IEP mRNA:increased expression:dental pulp (rat) RGD PMID:16109995 RGD:7775038 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:brain, astrocyte RGD PMID:20043976 RGD:5508788 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19102
    Stomatognathic Diseases 1366
      tooth disease 463
        dental pulp disease 10
          Dental Pulp Exposure 6
Path 2
Term Annotations click to browse term
  disease 19102
    Pathological Conditions, Signs and Symptoms 13607
      Signs and Symptoms 11167
        Neurologic Manifestations 10421
          sensory system disease 7330
            mouth disease 1037
              tooth disease 463
                dental pulp disease 10
                  Dental Pulp Exposure 6
paths to the root