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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:post-traumatic stress disorder
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Accession:DOID:2055 term browser browse the term
Definition:An anxiety disorder which results from a traumatic experience that results in psychological trauma. (DO)
Synonyms:exact_synonym: PTSD;   acute post traumatic stress disorder;   chronic post traumatic stress disorder;   delayed onset post traumatic stress disorder;   post-traumatic neuroses;   posttraumatic neuroses;   posttraumatic stress disorder;   posttraumatic stress disorders;   traumatic neurosis
 primary_id: MESH:D013313
 xref: EFO:0001358;   ICD10CM:F43.1;   ICD9CM:309.81;   NCI:C3389
For additional species annotation, visit the Alliance of Genome Resources.

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post-traumatic stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820 		JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility
treatment		 ISO DNA:missense mutation:cds:196G>A (p.V66M) (human) RGD PMID:23319005 PMID:28791385 RGD:10059367 RGD:401940159 NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Post-traumatic stress disorder ClinVar PMID:32332995 NCBI chrNW_004936606:2,168,104...2,867,560
Ensembl chrNW_004936606:2,168,625...2,865,758 		JBrowse link
G Casp9 caspase 9 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004936474:3,178,097...3,196,130 JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34262461 NCBI chrNW_004936510:3,779,930...3,806,615
Ensembl chrNW_004936510:3,781,210...3,802,693 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34262461 NCBI chrNW_004936474:9,019,044...9,020,110
Ensembl chrNW_004936474:9,019,067...9,020,110 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Post-traumatic stress disorder ClinVar PMID:18349090 NCBI chrNW_004936476:23,611,166...23,702,283
Ensembl chrNW_004936476:23,640,355...23,700,314 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit disease_progression ISO RGD PMID:27421892 RGD:405255654 NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A treatment ISO RGD PMID:28791385 RGD:401940159 NCBI chrNW_004936530:8,286,101...8,612,183
Ensembl chrNW_004936530:8,287,574...8,608,343 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004936487:13,348,465...13,352,717
Ensembl chrNW_004936487:13,348,465...13,352,717 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:21714072 RGD:5147887 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625 		JBrowse link
G Mdm2 MDM2 proto-oncogene ISO RGD PMID:23174211 RGD:10412309 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO mRNA, protein:altered expression:locus coeruleus (rat) RGD PMID:21584742 RGD:5686336 NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO protein:increased expression:hippocampus RGD PMID:20863519 RGD:5684783 NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928 		JBrowse link
G Oprm1 opioid receptor mu 1 severity ISO DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) RGD PMID:22143634 RGD:401827931 NCBI chrNW_004936489:6,506,207...6,567,136
Ensembl chrNW_004936489:6,506,207...6,548,946 		JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004936471:6,809,181...6,834,189
Ensembl chrNW_004936471:6,809,195...6,836,169 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 treatment ISO RGD PMID:28791385 RGD:401940159 NCBI chrNW_004936524:2,717,885...2,720,874
Ensembl chrNW_004936524:2,715,769...2,721,085 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein treatment ISO RGD PMID:17968352 RGD:8694407 NCBI chrNW_004936477:18,339,915...18,364,973
Ensembl chrNW_004936477:18,339,827...18,364,998 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14615
    disease of anatomical entity 14320
      nervous system disease 12594
        central nervous system disease 11248
          brain disease 10565
            disease of mental health 7572
              cognitive disorder 2008
                anxiety disorder 110
                  post-traumatic stress disorder 19
Path 2
Term Annotations click to browse term
  disease 14615
    disease of anatomical entity 14320
      nervous system disease 12594
        central nervous system disease 11248
          brain disease 10565
            disease of mental health 7572
              cognitive disorder 2008
                anxiety disorder 110
                  acute stress disorder 22
                    post-traumatic stress disorder 19
paths to the root