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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:duodenal ulcer
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Accession:DOID:1724 term browser browse the term
Definition:A PEPTIC ULCER located in the DUODENUM.
Synonyms:exact_synonym: Curling Ulcer;   Curling's ulcer;   Curling's ulcers;   Curlings Ulcer;   duodenal ulcers;   stress ulcer
 primary_id: MESH:D004381
 xref: EFO:0004607;   ICD10CM:K26;   ICD9CM:532;   NCI:C26755
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
duodenal ulcer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22387998 NCBI chr 2:26,732,508...26,754,973
Ensembl chr 2:26,732,515...26,754,991 		JBrowse link
G Aco1 aconitase 1 ISO protein:increased activity:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator ISO RGD PMID:15905414 RGD:1599596 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Egr1 early growth response 1 IMP RGD PMID:24385009 RGD:8694318 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Il27 interleukin 27 ISO associated with Helicobacter Infections;protein:increased expression:blood serum (human) RGD PMID:31702083 RGD:126790551 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:12481160 PMID:17045617 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18451993 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Psca prostate stem cell antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22387998 NCBI chr15:74,586,688...74,588,914
Ensembl chr15:74,586,688...74,588,918 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12481160 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 ISO mRNA, protein:increased expression:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RGD PMID:24385009 RGD:8694318 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tfrc transferrin receptor ISO protein:increased expression:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12868675 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Candidiasis;protein:decreased expression:Duodenum: RGD PMID:18622701 RGD:7483560 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16106
    disease of anatomical entity 15662
      gastrointestinal system disease 6788
        stomach disease 1077
          peptic ulcer disease 89
            duodenal ulcer 14
              Duodenal Ulcer due to Antral G-Cell Hyperfunction 0
              Duodenal Ulcer, Hyperpepsinogenemic I 0
              Neuhauser Daly Magnelli Syndrome 0
Path 2
Term Annotations click to browse term
  disease 16106
    disease of anatomical entity 15662
      gastrointestinal system disease 6788
        intestinal disease 3039
          duodenum disease 94
            peptic ulcer disease 89
              duodenal ulcer 14
                Duodenal Ulcer due to Antral G-Cell Hyperfunction 0
                Duodenal Ulcer, Hyperpepsinogenemic I 0
                Neuhauser Daly Magnelli Syndrome 0
paths to the root