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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyazofamid
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Accession:CHEBI:81841 term browser browse the term
Definition:A member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.
Synonyms:exact_synonym: 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide
 related_synonym: 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide;   Formula=C13H13ClN4O2S;   InChI=1S/C13H13ClN4O2S/c1-9-4-6-10(7-5-9)12-13(14)16-11(8-15)18(12)21(19,20)17(2)3/h4-7H,1-3H3;   InChIKey=YXKMMRDKEKCERS-UHFFFAOYSA-N;   SMILES=CN(C)S(=O)(=O)n1c(nc(Cl)c1-c1ccc(C)cc1)C#N
 xref: CAS:120116-88-3;   KEGG:C18573
 xref_mesh: MESH:C465366
 xref: PMID:11852638;   PMID:12639045;   PMID:23919901;   PMID:24176337;   PMID:25173365;   PPDB:186;   Patent:CN101647451;   Pesticides:cyazofamid;   Reaxys:9064229


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cyazofamid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of cyazofamid
cyazofamid affects the reaction [ABCB1 protein results in increased uptake of Digoxin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]
CTD PMID:32003934 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases uptake ISO ABCC2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases uptake ISO ABCG2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO cyazofamid results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Esrra estrogen related receptor, alpha increases activity ISO cyazofamid results in increased activity of ESRRA protein CTD PMID:20143881 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:32003934 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO cyazofamid inhibits the reaction [SLCO1B3 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pesticide 16979
          antifungal agrochemical 8462
            cyazofamid 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  heteroarene 16530
                                    monocyclic heteroarene 13437
                                      azole 12628
                                        diazole 8394
                                          imidazoles 7687
                                            imidazole antifungal agent 1301
                                              imidazole fungicide 656
                                                cyazofamid 8
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