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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyazofamid
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Accession:CHEBI:81841 term browser browse the term
Definition:A member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.
Synonyms:exact_synonym: 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide
 related_synonym: 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide;   Formula=C13H13ClN4O2S;   InChI=1S/C13H13ClN4O2S/c1-9-4-6-10(7-5-9)12-13(14)16-11(8-15)18(12)21(19,20)17(2)3/h4-7H,1-3H3;   InChIKey=YXKMMRDKEKCERS-UHFFFAOYSA-N;   SMILES=CN(C)S(=O)(=O)n1c(nc(Cl)c1-c1ccc(C)cc1)C#N
 xref: CAS:120116-88-3;   KEGG:C18573
 xref_mesh: MESH:C465366
 xref: PMID:11852638;   PMID:12639045;   PMID:23919901;   PMID:24176337;   PMID:25173365;   PPDB:186;   Patent:CN101647451;   Pesticides:cyazofamid;   Reaxys:9064229



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cyazofamid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of cyazofamid
cyazofamid affects the reaction [ABCB1 protein results in increased uptake of Digoxin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]
CTD PMID:32003934 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases uptake ISO ABCC2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases uptake ISO ABCG2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO cyazofamid results in decreased expression of CYP3A5 mRNA CTD PMID:34642769 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO cyazofamid results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Esrra estrogen related receptor, alpha increases activity ISO cyazofamid results in increased activity of ESRRA protein CTD PMID:20143881 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:32003934 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO cyazofamid inhibits the reaction [SLCO1B3 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        pesticide 17304
          antifungal agrochemical 8777
            cyazofamid 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  heteroarene 16628
                                    monocyclic heteroarene 13606
                                      azole 12836
                                        diazole 8631
                                          imidazoles 7724
                                            imidazole antifungal agent 1301
                                              imidazole fungicide 656
                                                cyazofamid 9
paths to the root