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Hsp90 inhibitor - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Hsp90 inhibitor
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Accession:CHEBI:63962 term browser browse the term
Definition:An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90.
Synonyms:related_synonym: Hsp90 inhibitors;   heat shock protein 90 inhibitor;   heat shock protein 90 inhibitors
 xref: PMID:19860732;   PMID:19946660;   PMID:22035754;   PMID:22920907;   PMID:22959035;   PMID:23160336;   PMID:23312026;   Wikipedia:Hsp90_inhibitors


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      CHEBI ontology 19887
        role 19858
          biological role 19856
            biochemical role 19566
              enzyme inhibitor 18760
                EC 3.* (hydrolase) inhibitor 18358
                  EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor 5796
                    EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor 2996
                      EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor 2983
                        Hsp90 inhibitor 2983
                          (-)-epigallocatechin 3-gallate + 2277
                          4-chloro-6-\{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl\}benzene-1,3-diol 0
                          5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide 0
                          8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-yn-1-yl-9H-purin-6-amine 0
                          BIIB021 0
                          CCT-018159 0
                          ICPD-26 0
                          ICPD-47 0
                          SB 203580 437
                          SH-1242 0
                          SH-1280 0
                          alvespimycin 0
                          celastrol 237
                          coumermycin A1 9
                          dicoumarol 38
                          ethoxyquin 42
                          gamendazole 2
                          gedunin + 83
                          geldanamycin + 485
                          herbimycin 30
                          luminespib 0
                          monascorubrin 0
                          oleocanthal 0
                          onalespib 0
                          retaspimycin 0
                          retaspimycin hydrochloride 0
                          tanespimycin 144
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