Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-bromo-2-(bromomethyl)pentanedinitrile
go back to main search page
Accession:CHEBI:62823 term browser browse the term
Definition:An organobromine compound that consists of pentanedinitrile bearing bromo and bromomethyl substituents at position 2.
Synonyms:related_synonym: 1,2-Dibromo-2,4-dicyanobutane;   1-Bromo-1-(bromomethyl)-1,3-propanedicarbonitrile;   2-Bromo-2-(bromomethyl)glutaronitrile;   2-Bromo-2-bromomethylglutaronitrile;   Bromothalonil;   Formula=C6H6Br2N2;   InChI=1S/C6H6Br2N2/c7-4-6(8,5-10)2-1-3-9/h1-2,4H2;   InChIKey=DHVLDKHFGIVEIP-UHFFFAOYSA-N;   MDGN;   Methyldibromo glutaronitrile;   Methyldibromoglutaronitrile;   SMILES=BrCC(Br)(CCC#N)C#N
 xref: CAS:35691-65-7
 xref_mesh: MESH:C039411
 xref: PMID:19321115;   PMID:19426617;   PMID:19457305;   PMID:19470301;   PMID:19883218;   PMID:20233547;   PMID:20940038;   PMID:21144344;   PMID:21317857;   PMID:21325848;   PMID:21332463;   PMID:21569742;   PMID:21616561;   PMID:29079364;   Patent:CN101595876;   Patent:CN101595879;   Patent:CN101617668;   Patent:CN101642109;   Patent:EP1188377;   Reaxys:1930600;   Wikipedia:Methyldibromo_glutaronitrile


show annotations for term's descendants           Sort by:
2-bromo-2-(bromomethyl)pentanedinitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of ATF3 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of GCLM mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:26244607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Il18 interleukin 18 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of IL1B mRNA CTD PMID:33715048 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    role 19820
      biological role 19818
        aetiopathogenetic role 19194
          sensitiser 9856
            2-bromo-2-(bromomethyl)pentanedinitrile 8
              Euxyl K 400 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            one-carbon compound 17848
                              hydrogen cyanide 4788
                                cyanides 4771
                                  nitrile 4572
                                    aliphatic nitrile 2198
                                      2-bromo-2-(bromomethyl)pentanedinitrile 8
                                        Euxyl K 400 0
paths to the root