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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-bromo-2-(bromomethyl)pentanedinitrile
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Accession:CHEBI:62823 term browser browse the term
Definition:An organobromine compound that consists of pentanedinitrile bearing bromo and bromomethyl substituents at position 2.
Synonyms:related_synonym: 1,2-Dibromo-2,4-dicyanobutane;   1-Bromo-1-(bromomethyl)-1,3-propanedicarbonitrile;   2-Bromo-2-(bromomethyl)glutaronitrile;   2-Bromo-2-bromomethylglutaronitrile;   Bromothalonil;   Formula=C6H6Br2N2;   InChI=1S/C6H6Br2N2/c7-4-6(8,5-10)2-1-3-9/h1-2,4H2;   InChIKey=DHVLDKHFGIVEIP-UHFFFAOYSA-N;   MDGN;   Methyldibromo glutaronitrile;   Methyldibromoglutaronitrile;   SMILES=BrCC(Br)(CCC#N)C#N
 xref: CAS:35691-65-7
 xref_mesh: MESH:C039411
 xref: PMID:19321115;   PMID:19426617;   PMID:19457305;   PMID:19470301;   PMID:19883218;   PMID:20233547;   PMID:20940038;   PMID:21144344;   PMID:21317857;   PMID:21325848;   PMID:21332463;   PMID:21569742;   PMID:21616561;   PMID:29079364;   Patent:CN101595876;   Patent:CN101595879;   Patent:CN101617668;   Patent:CN101642109;   Patent:EP1188377;   Reaxys:1930600;   Wikipedia:Methyldibromo_glutaronitrile


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2-bromo-2-(bromomethyl)pentanedinitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of ATF3 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of GCLM mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:26244607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Il18 interleukin 18 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of IL1B mRNA CTD PMID:33715048 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 1,2-dibromo-2,4-dicyanobutane results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        aetiopathogenetic role 19213
          sensitiser 9853
            2-bromo-2-(bromomethyl)pentanedinitrile 8
              Euxyl K 400 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            one-carbon compound 17886
                              hydrogen cyanide 4795
                                cyanides 4778
                                  nitrile 4575
                                    aliphatic nitrile 2206
                                      2-bromo-2-(bromomethyl)pentanedinitrile 8
                                        Euxyl K 400 0
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