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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isoscutellarein
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Accession:CHEBI:6059 term browser browse the term
Definition:A tetrahydroxyflavone that is apigenin with an extra hydroxy group at position 8.
Synonyms:exact_synonym: 5,7,8-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 8-Hydroxyapigenin;   Formula=C15H10O6;   InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)12-6-10(18)13-9(17)5-11(19)14(20)15(13)21-12/h1-6,16-17,19-20H;   InChIKey=NXHQVROAKYDSNW-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(O)c2o1
 xref: CAS:41440-05-5;   KEGG:C10097;   KNApSAcK:C00003848;   LIPID_MAPS_instance:LMPK12111361
 xref_mesh: MESH:C000722867
 xref: PMID:1814628;   PMID:22146136;   Reaxys:304400


show annotations for term's descendants           Sort by:
isoscutellarein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO isoscutellarein results in increased expression of ADIPOQ protein CTD PMID:30445784 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Lep leptin decreases expression ISO isoscutellarein results in decreased expression of LEP protein CTD PMID:30445784 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO isoscutellarein results in decreased expression of RBP4 protein CTD PMID:30445784 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO isoscutellarein results in increased expression of SLC2A4 protein CTD PMID:30445784 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO isoscutellarein results in decreased expression of TNF protein CTD PMID:30445784 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    role 19820
      biological role 19818
        biochemical role 19525
          metabolite 19512
            isoscutellarein 5
              isoscutellarein glycoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            organic molecule 19687
                              organic cyclic compound 19498
                                organic heterocyclic compound 18870
                                  oxacycle 17888
                                    benzopyran 11971
                                      1-benzopyran 11724
                                        flavonoid 7206
                                          anthoxanthin 4545
                                            flavones 4545
                                              hydroxyflavone 4518
                                                trihydroxyflavone 430
                                                  apigenin 292
                                                    isoscutellarein 5
                                                      isoscutellarein glycoside 0
paths to the root