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propidium - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:propidium
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Accession:CHEBI:51246 term browser browse the term
Definition:A phenanthridine that has formula 414.58582.
Synonyms:exact_synonym: 3,8-diamino-5-{3-[diethyl(methyl)ammonio]propyl}-6-phenylphenanthridinium
 related_synonym: 3,8-DIAMINO-5[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM;   Formula=C27H34N4;   InChI=1S/C27H33N4/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3/q+1/p+1;   InChIKey=ZDWVWKDAWBGPDN-UHFFFAOYSA-O;   SMILES=CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc12
 alt_id: CHEBI:45031;   CHEBI:51242
 xref: Beilstein:3729792;   CAS:36015-30-2;   DrugBank:DB02166;   LINCS:LSM-5329
 xref_mesh: MESH:D011419
 xref: PDBeChem:PRM

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propidium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity 		ISO Propidium binds to and results in decreased activity of ACHE protein; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Propidium promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Propidium promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
Propidium results in decreased activity of ACHE protein 		CTD PMID:10421444 PMID:25522658 PMID:27238725 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase decreases activity ISO Propidium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Propidium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Propidium results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Propidium results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Propidium results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Propidium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Propidium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        dye 3014
          fluorescent dye 2153
            fluorochrome 236
              propidium 8
                propidium iodide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            organic molecule 20649
                              organic cyclic compound 20400
                                organic heterocyclic compound 19383
                                  organic heteropolycyclic compound 18642
                                    organic heterotricyclic compound 16038
                                      dibenzopyridine 176
                                        phenanthridines 59
                                          propidium 8
                                            propidium iodide 0
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