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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethoprophos
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Accession:CHEBI:38665 term browser browse the term
Definition:An organothiophosphate insecticide that has formula C8H19O2PS2.
Synonyms:exact_synonym: O-ethyl S,S-dipropyl phosphorodithioate
 related_synonym: Ethoprop;   Formula=C8H19O2PS2;   InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3;   InChIKey=VJYFKVYYMZPMAB-UHFFFAOYSA-N;   O-ethyl S,S-dipropyl dithiophosphate;   Phosphorodithioic acid, O-ethyl S,S-dipropyl ester;   SMILES=CCCSP(=O)(OCC)SCCC
 xref: Beilstein:8139788;   CAS:13194-48-4;   KEGG:C18687;   LINCS:LSM-2169
 xref_mesh: MESH:C474843
 xref: PPDB:279


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ethoprophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO
EXP		 ethoprop metabolite results in decreased activity of ACHE protein; ethoprop results in decreased activity of ACHE protein CTD PMID:30625376 PMID:33720374 PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Anxa10 annexin A10 increases expression ISO ethoprop results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Arg1 arginase 1 decreases expression ISO ethoprop results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO ethoprop results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO ethoprop results in decreased expression of CYP7A1 mRNA; ethoprop results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO ethoprop results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO ethoprop binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    role 19820
      application 19663
        agrochemical 16258
          ethoprophos 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      chalcogen 19548
                        oxygen atom 19491
                          oxygen molecular entity 19523
                            hydroxides 19331
                              oxoacid 18762
                                pnictogen oxoacid 14895
                                  phosphorus oxoacid 14485
                                    phosphoric acids 11416
                                      phosphoric acid 13924
                                        phosphoric acid derivative 13830
                                          phosphate 13829
                                            organic phosphate 13829
                                              organic thiophosphate 8611
                                                ethoprophos 7
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