CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: kresoxim-methyl
Accession: CHEBI:2962
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Definition: A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.
Synonyms: exact_synonym: methyl (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetate
related_synonym: BAS 490 F; Formula=C18H19NO4; InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+; InChIKey=ZOTBXTZVPHCKPN-HTXNQAPBSA-N; Methyl (E)-alpha-(methoxyimino)-2-((2-methylphenoxy)methyl)benzeneacetate; SMILES=CO\\N=C(\\C(=O)OC)c1ccccc1COc1ccccc1C; methyl (E)-methoxyimino[alpha-(o-tolyloxy)-o-tolyl]acetate; methyl (alphaE)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetate
xref: CAS:143390-89-0; KEGG:C11017
xref_mesh: MESH:C469328
xref: PMID:23197469; PMID:23277369; PMID:23452212; PMID:24061350; PMID:24210350; PMID:24611510; PMID:24936710; PMID:24997920; PPDB:414; Pesticides:kresoxim-methyl; Reaxys:8330581
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Esr2
estrogen receptor 2
multiple interactions
ISO
kresoxim-methyl inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
CTD
PMID:30818834
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esrra
estrogen related receptor, alpha
multiple interactions
ISO
kresoxim-methyl inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; kresoxim-methyl inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]
CTD
PMID:30818834
NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
G
Gpx1
glutathione peroxidase 1
decreases activity
ISO
kresoxim-methyl results in decreased activity of GPX1 protein
CTD
PMID:30064279
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
kresoxim-methyl results in increased activity of NFE2L2 protein
CTD
PMID:30818834
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Pgr
progesterone receptor
multiple interactions
ISO
kresoxim-methyl inhibits the reaction [Promegestone results in increased activity of PGR protein]
CTD
PMID:30818834
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
kresoxim-methyl inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein]
CTD
PMID:30818834
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
multiple interactions
ISO
kresoxim-methyl inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]
CTD
PMID:30818834
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Thrb
thyroid hormone receptor beta
affects binding
ISO
kresoxim-methyl binds to THRB protein
CTD
PMID:28973306
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
G
Tp53
tumor protein p53
increases activity
ISO
kresoxim-methyl results in increased activity of TP53 protein
CTD
PMID:30818834
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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