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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isopimpinellin
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Accession:CHEBI:28853 term browser browse the term
Definition:A psoralen that has formula C13H10O5.
Synonyms:exact_synonym: 4,9-dimethoxy-7H-furo[3,2-g]chromen-7-one
 related_synonym: 5,8-Dimethoxypsoralen;   5,8-Dimethoxypsoralene;   Formula=C13H10O5;   InChI=1S/C13H10O5/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11/h3-6H,1-2H3;   InChIKey=DFMAXQKDIGCMTL-UHFFFAOYSA-N;   SMILES=COc1c2ccoc2c(OC)c2oc(=O)ccc12
 alt_id: CHEBI:23815;   CHEBI:6040
 xref: Beilstein:262337;   CAS:482-27-9;   KNApSAcK:C00000583;   LINCS:LSM-25618
 xref_mesh: MESH:C015304


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isopimpinellin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity EXP isopimpinellin results in increased activity of AHR protein CTD PMID:15670584 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO
EXP		 isopimpinellin results in increased expression of CYP1A1 protein
isopimpinellin results in increased expression of and results in decreased activity of CYP1A1 protein
isopimpinellin results in increased expression of CYP1A1 mRNA		 CTD PMID:15670584 PMID:18692084 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO isopimpinellin results in increased expression of CYP1A2 protein CTD PMID:18692084 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases activity		 ISO isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]
isopimpinellin results in decreased activity of CYP1B1 protein; isopimpinellin results in decreased activity of CYP1B1 protein polymorphism		 CTD PMID:15861043 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression		 ISO NR1I3 protein affects the reaction [isopimpinellin results in increased expression of CYP2B10 mRNA]
isopimpinellin results in increased expression of CYP2B10 mRNA; isopimpinellin results in increased expression of CYP2B10 protein		 CTD PMID:18692084 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO isopimpinellin results in increased expression of GSTP1 mRNA CTD PMID:18692084 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO isopimpinellin inhibits the reaction [Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]]; isopimpinellin promotes the reaction [NR1I3 protein binds to NCOA1 protein] CTD PMID:18692084 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO isopimpinellin results in increased expression of NQO1 protein CTD PMID:19150646 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO isopimpinellin results in increased activity of NR1I2 protein CTD PMID:18692084 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity		 ISO isopimpinellin inhibits the reaction [Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]]; isopimpinellin inhibits the reaction [Androstenedione results in decreased activity of NR1I3 protein]; isopimpinellin promotes the reaction [NR1I3 protein binds to NCOA1 protein]; NR1I3 protein affects the reaction [isopimpinellin results in increased expression of CYP2B10 mRNA]
isopimpinellin results in increased activity of NR1I3 protein		 CTD PMID:18692084 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    chemical entity 19877
      atom 19877
        nonmetal atom 19800
          oxygen atom 19541
            oxygen molecular entity 19541
              organooxygen compound 19199
                oxacycle 17911
                  furochromene 135
                    furanocoumarin 135
                      psoralens 127
                        isopimpinellin 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      carbon group element atom 19756
                        carbon atom 19753
                          organic molecular entity 19753
                            organic molecule 19706
                              organic cyclic compound 19498
                                organic heterocyclic compound 18878
                                  organic heteropolycyclic compound 18305
                                    organic heterotricyclic compound 15863
                                      furochromene 135
                                        furanocoumarin 135
                                          psoralens 127
                                            isopimpinellin 10
paths to the root