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Pathways
Genes search result for Rattus norvegicus
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48 records found for search term Prep
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
620841Prepprolyl endopeptidaseENCODES a protein that exhibits endopeptidase activity; peptide binding; metallocarboxypeptidase activity (ortholog); INVOLVED IN protein catabolic process; angiotensin maturation (ortholog); ASSOCIATED WITH depressive disorder; amnestic disorder (ortholog); Disease Progression (ortholog); FOUND IN 205013858850235549Rat144symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1310143Preplprolyl endopeptidase-likeENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN Golgi to plasma membrane protein transport (ortholog); regulation of synaptic vesicle exocytosis (ortholog); retrograde transport, endosome to Golgi (ortholog); ASSOCIATED WITH congenital myasthenic syndrome (ortholog); conge61533310715362825Rat124symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
2534Edn3endothelin 3ENCODES a protein that exhibits endothelin B receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN negative regulation of hormone secretion; regulation of neurotransmitter secretion; artery smooth muscle contraction (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED3183980458184004958Rat161old_gene_name , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
3362PnocprepronociceptinENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to ethanol; chemical synaptic transmission; ASSOCIATED WITH abnormal conditioned place preference behavior; abnormal drug-induced reinstatement of an extinguished operan154380024043827841Rat177old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
3193Nppanatriuretic peptide AENCODES a protein that exhibits hormone activity; signaling receptor binding; hormone receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to angiotensin; cellular response to glucose stimulus; PARTICIPATES IN atrial natriuretic peptide 5163712184163713493Rat559old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3194Nppbnatriuretic peptide BENCODES a protein that exhibits hormone receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to mechanical stimulus; cGMP metabolic process; PARTICIPATES IN brain natriuretic peptide signaling pathw5163699955163701314Rat498old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
2786Hcrthypocretin neuropeptide precursorENCODES a protein that exhibits neuropeptide hormone activity; type 1 orexin receptor binding; type 2 orexin receptor binding; INVOLVED IN behavioral response to ethanol; drinking behavior; eating behavior; PARTICIPATES IN orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/108619028986191524Rat147old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3579Rln1relaxin 1ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of apoptotic process; regulation of cell population proliferation; ASSOCIATED WITH Hypertrophy (ortholog); FOUND IN extrac1236493532236496541Rat67old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
620888Nucb2nucleobindin 2ENCODES a protein that exhibits G-protein alpha-subunit binding; guanyl-nucleotide exchange factor activity; tumor necrosis factor receptor binding; INVOLVED IN insulin metabolic process; negative regulation of appetite; negative regulation of cAMP/PKA signal transduction; ASSOCIATED WITH alcohol de1180185121180221644Rat212old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1308379Ctrcchymotrypsin CENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); proteolysis (ortholog); ASSOCIATED WITH chronic pancreatitis (ortholog); Hereditary Pancreatitis (ortholog); INTERACTS WITH 17be5159430333159439557Rat67old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
62054PdynprodynorphinENCODES a protein that exhibits opioid peptide activity (inferred); INVOLVED IN locomotion involved in locomotory behavior; response to ethanol; response to immobilization stress; ASSOCIATED WITH alcohol dependence; alcohol use disorder; alcohol withdrawal syndrome; FOUND IN axon terminus; dendritic3137354161137366503Rat288old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3175Klk1b3kallikrein 1-related peptidase B3ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH hypertension; INTERACTS WITH 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil; bacitracin1103845647103849854Rat48old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
2383CortcortistatinENCODES a protein that exhibits neuropeptide hormone activity; G protein-coupled receptor binding (ortholog); INVOLVED IN neuropeptide signaling pathway; regulation of circadian sleep/wake cycle, sleep; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED 5164843682164845796Rat70old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2184Avparginine vasopressinENCODES a protein that exhibits neuropeptide hormone activity; V1A vasopressin receptor binding; V1B vasopressin receptor binding; INVOLVED IN grooming behavior; locomotory behavior; maternal aggressive behavior; PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via recept3138246544138248522Rat341old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2532Edn1endothelin 1ENCODES a protein that exhibits endothelin A receptor binding; endothelin B receptor binding; cytokine activity (ortholog); INVOLVED IN artery smooth muscle contraction; cellular response to calcium ion; cellular response to fatty acid; PARTICIPATES IN inflammatory response pathway; endothelin signa172266079922666687Rat1127old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2533Edn2endothelin 2ENCODES a protein that exhibits endothelin B receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN negative regulation of hormone secretion; ovarian follicle rupture; phospholipase C-activating G protein-coupled receptor signaling pathway; PARTICIPATES IN endothelin signaling pathway5139036576139042074Rat178old_gene_namegene, protein-coding, VALIDATED [RefSeq]
628842Tac4tachykinin precursor 4ENCODES a protein that exhibits receptor ligand activity (ortholog); signaling receptor binding (ortholog); substance K receptor binding (ortholog); INVOLVED IN detection of temperature stimulus involved in sensory perception of pain; positive regulation of sensory perception of pain; negative regul108070464080712972Rat73old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1307076Cntnap2contactin associated protein 2ENCODES a protein that exhibits protease binding; transmembrane transporter binding; enzyme binding (ortholog); INVOLVED IN prepulse inhibition; startle response; action potential initiation (ortholog); ASSOCIATED WITH abnormal auditory brainstem response; abnor47510935877366258Rat301descriptiongene, protein-coding, VALIDATED [RefSeq]
2272CartptCART prepropeptideENCODES a protein that exhibits neuropeptide hormone activity (inferred); INVOLVED IN adult feeding behavior; behavioral response to cocaine; cAMP biosynthetic process; ASSOCIATED WITH amnestic disorder; amphetamine abuse; cerebral infarction; FOUND IN cytoplasm; extracellular space; neuronal cell b23298921532991794Rat238namegene, protein-coding, VALIDATED [RefSeq]
620983Oprpnopiorphin prepropeptideENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog); peptidase inhibitor activity (ortholog); INVOLVED IN regulation of sensory perception of pain (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; C60 fullerene141998657520001589Rat25namegene, protein-coding, VALIDATED [RefSeq]
61954Galgalanin and GMAP prepropeptideENCODES a protein that exhibits galanin receptor activity (ortholog); neuropeptide hormone activity (ortholog); type 1 galanin receptor binding (ortholog); INVOLVED IN behavioral response to ethanol; drinking behavior; feeding behavior; ASSOCIATED WITH alcohol use disorder; alcohol withdrawal syndro1210079709210084572Rat288old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
632283Ghrlghrelin and obestatin prepropeptideENCODES a protein that exhibits G protein-coupled receptor binding; ghrelin receptor binding; growth hormone-releasing hormone activity; INVOLVED IN G protein-coupled receptor signaling pathway; gastric acid secretion; negative regulation of apoptotic process; PARTICIPATES IN ghrelin system pathway;4148421315148431128Rat297old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
3238Oxtoxytocin/neurophysin I prepropeptideENCODES a protein that exhibits neuropeptide hormone activity; oxytocin receptor binding; INVOLVED IN drinking behavior; eating behavior; female pregnancy; PARTICIPATES IN oxytocin signaling pathway; ASSOCIATED WITH amphetamine abuse; Burns; Dehydration; FOUND IN extracellular space; neuronal dense 3138235754138236594Rat217old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1308862Sec62SEC62 preprotein translocation factorINVOLVED IN post-translational protein targeting to endoplasmic reticulum membrane (ortholog); post-translational protein targeting to membrane, translocation (ortholog); reticulophagy (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN membrane (ortholog); INT2114499317114526705Rat129old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
708513Npbneuropeptide BENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); FOUND IN anaphase-promoting complex (inferred); extracellular region (inferred); nucleolus (inferred); INTERA10106382307106385566Rat65old_gene_namegene, protein-coding, VALIDATED [RefSeq]
727858Npwneuropeptide WENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN G protein-coupled receptor signaling pathway; feeding behavior (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil101418481914186155Rat40old_gene_namegene, protein-coding, VALIDATED [RefSeq]
68946PenkproenkephalinENCODES a protein that exhibits opioid peptide activity; receptor ligand activity (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to cAMP; cellular response to oxidative stress; ASSOCIATED WITH alcohol use disorder; Anhedonia; Catalepsy; FOUND IN axon; axon terminus; cell b52198138121987074Rat289old_gene_namegene, protein-coding, VALIDATED [RefSeq]
7085851810009J06RiklRIKEN cDNA 1810009J06 gene likeENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN digestion (inferred); proteolysis (inferred); FOUND IN extracellular region (inferred)47078178370792997Rat13old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
2024AcracrosinENCODES a protein that exhibits amidase activity (ortholog); D-mannose binding (ortholog); fucose binding (ortholog); INVOLVED IN acrosome matrix dispersal; penetration of zona pellucida; protein catabolic process; ASSOCIATED WITH decreased litter size; impaired acrosome reaction; ASSOCIATED WITH sp7122517910122524110Rat83old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2130Apoa1apolipoprotein A1ENCODES a protein that exhibits amyloid-beta binding; cholesterol transfer activity; lipase inhibitor activity; INVOLVED IN animal organ regeneration; cholesterol transport; negative regulation of lipase activity; PARTICIPATES IN altered lipoprotein metabolic pathway; forkhead class A signaling path85542394555425729Rat683old_gene_namegene, protein-coding, VALIDATED [RefSeq]
621512Gdf10growth differentiation factor 10ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); INVOLVED IN cerebellum development; osteoblast differentiation; ovulation cycle; ASSOCIATED WITH Arterial Occlusive Diseases (ortholog); Breast Neoplasms (ortholog); Mesothelioma (ortholog); FOUND IN ext1692434349256788Rat141old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
2917Insrinsulin receptorENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; cargo receptor activity; insulin binding; INVOLVED IN amyloid-beta clearance; cellular response to zinc ion starvation; cerebellum development; PARTICIPATES IN altered leptin system pathway; insulin signaling pathwa1259911356129275Rat653old_gene_namegene, protein-coding, VALIDATED [RefSeq]
61998Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, betaENCODES a protein that exhibits protein-containing complex binding; enzyme binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription; negative regulation of G protein-coupled receptor signaling pathway (ortholog); negative regulation o3173078904173101508Rat214old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
628634Prlhprolactin releasing hormoneENCODES a protein that exhibits neuropeptide hormone activity; prolactin-releasing peptide receptor binding; INVOLVED IN feeding behavior; G protein-coupled receptor signaling pathway; reduction of food intake in response to dietary excess; PARTICIPATES IN obesity pathway; ASSOCIATED WITH obesity; F99899162898996515Rat42old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1593461Klk5kallikrein related-peptidase 5ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN antibacterial peptide biosynthetic process (ortholog); positive regulation of G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (orthol1103432743103442011Rat57old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1566350Cdh12cadherin 12ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane (27220185973436039Rat69old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3862Timm17atranslocase of inner mitochondrial membrane 17AENCODES a protein that exhibits enzyme binding; INVOLVED IN positive regulation of protein processing; PARTICIPATES IN presequence pathway of mitochondrial protein import; FOUND IN mitochondrial inner membrane; mitochondrion (ortholog); TIM23 mitochondrial import inner membrane translocase complex (134928291849296363Rat123old_gene_namegene, protein-coding, VALIDATED [RefSeq]
11568647Cntnap2em1Sagecontactin associated protein-like 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering LabsASSOCIATED WITH abnormal auditory brainstem response; abnormal habituation; abnormal prepulse inhibition; ASSOCIATED WITH autism spectrum disorder; epilepsyRat11descriptiongene, allele
2290090Nrg1Tn(sb-T2/Bart3)2.183Mcwineuregulin 1; transposon insertion 2.183, Medical College of WisconsinASSOCIATED WITH abnormal habituation; decreased locomotor activity; decreased prepulse inhibition; ASSOCIATED WITH stress-related disorderRat8descriptiongene, allele
14694849Pvalbem1(flpo)Berkeparvalbumin; CRISPR/Cas9 induced flpo knock in mutant1, BerkeA double-stranded DNA plasmid donor was synthesized to introduce self-cleaving peptide 2A (P2A),followed by Flpo recombinase,and the V5 peptide tag (GKPIPNPLLGLDST) before the termination codon in exon 5 of rat Parvalbumin. (ref:bioRxiv preprint first posted onlRatdescriptiongene, allele
1303022Tomm40translocase of outer mitochondrial membrane 40ENCODES a protein that exhibits monoatomic cation channel activity; preprotein binding; protein transmembrane transporter activity; INVOLVED IN positive regulation of apoptotic process; protein insertion into mitochondrial membrane; protein targeting to mitochon18848674588498833Rat152descriptiongene, protein-coding, VALIDATED [RefSeq]
1562006Tomm40ltranslocase of outer mitochondrial membrane 40 likeENCODES a protein that exhibits mitochondrion targeting sequence binding; preprotein binding; INVOLVED IN protein import into mitochondrial matrix (inferred); protein transport (inferred); transmembrane transport (inferred); FOUND IN mitochondrial outer membrane138616916086174121Rat78descriptiongene, protein-coding, VALIDATED [RefSeq]
1359376Kng1kininogen 1ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN negative regulation of blood coagulation (ortholog); negative regulation of cell adhesion (ortholog); negative regulation of prot119131735491340148Rat303old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
2870Igf2insulin-like growth factor 2ENCODES a protein that exhibits growth factor activity (ortholog); insulin receptor binding (ortholog); insulin-like growth factor receptor binding (ortholog); INVOLVED IN cellular response to mechanical stimulus; female pregnancy; memory; PARTICIPATES IN insulin-like growth factor signaling pathway1207243873207261263Rat482old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1559447Pth2parathyroid hormone 2INVOLVED IN neuropeptide signaling pathway (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; Cuprizon; trichloroethene1104802983104803632Rat22old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1359122Nmsneuromedin SENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN locomotor rhythm; neuropeptide signaling pathway; FOUND IN extracellular region (inferred); INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog); 1,2-dichloroethane (ortholog); 2,2',4,4',5,5'-hexachlor94866539848676461Rat15old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
68388Nmuneuromedin UENCODES a protein that exhibits neuromedin U receptor binding; type 1 neuromedin U receptor binding; type 2 neuromedin U receptor binding; INVOLVED IN eating behavior; energy homeostasis; gastric acid secretion; ASSOCIATED WITH obesity; FOUND IN terminal bouton; INTERACTS WITH 6-propyl-2-thiouracil;143219878932226397Rat163old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1560118Adamts18ADAM metallopeptidase with thrombospondin type 1 motif, 18ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN eye development (ortholog); negative regulation of platelet aggregation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy195859609558749239Rat73old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]