| 620841 | Prep | prolyl endopeptidase | ENCODES a protein that exhibits endopeptidase activity; peptide binding; metallocarboxypeptidase activity (ortholog); INVOLVED IN protein catabolic process; angiotensin maturation (ortholog); ASSOCIATED WITH depressive disorder; amnestic disorder (ortholog); Disease Progression (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-propyl-2-thiouracil; amitrole | 20 | 50138588 | 50235549 | Rat | 144 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310143 | Prepl | prolyl endopeptidase-like | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN Golgi to plasma membrane protein transport (ortholog); regulation of synaptic vesicle exocytosis (ortholog); retrograde transport, endosome to Golgi (ortholog); ASSOCIATED WITH congenital myasthenic syndrome (ortholog); conge nital myasthenic syndrome 22 (ortholog); genetic disease (ortholog); FOUND IN cytoskeleton (ortholog); Golgi apparatus (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 6 | 15333107 | 15362825 | Rat | 124 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2534 | Edn3 | endothelin 3 | ENCODES a protein that exhibits endothelin B receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN negative regulation of hormone secretion; regulation of neurotransmitter secretion; artery smooth muscle contraction (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH Bradycardia (ortholog); congenital central hypoventilation syndrome (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (R)-noradrenaline; 3',5'-cyclic GMP; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | 3 | 183980458 | 184004958 | Rat | 161 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3362 | Pnoc | prepronociceptin | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to ethanol; chemical synaptic transmission; ASSOCIATED WITH abnormal conditioned place preference behavior; abnormal drug-induced reinstatement of an extinguished operan t behavior for a drug reinforcer; alcohol preference; ASSOCIATED WITH Acute Alcohol Sensitivity; alcohol dependence; alcohol use disorder; FOUND IN synaptic membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 43800240 | 43827841 | Rat | 177 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3193 | Nppa | natriuretic peptide A | ENCODES a protein that exhibits hormone activity; signaling receptor binding; hormone receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to angiotensin; cellular response to glucose stimulus; PARTICIPATES IN atrial natriuretic peptide signaling pathway; ASSOCIATED WITH decreased body weight; increased heart weight; increased mean systemic arterial blood pressure; ASSOCIATED WITH acute kidney failure; Cardiomegaly; congestive heart failure; FOUND IN brush border; glycinergic synapse; mast cell granule; INTERACTS WITH (R)-noradrenaline; 1-octadec-9-enoylglycero-3-phosphate; 11-deoxycorticosterone | 5 | 163712184 | 163713493 | Rat | 559 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 3194 | Nppb | natriuretic peptide B | ENCODES a protein that exhibits hormone receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to mechanical stimulus; cGMP metabolic process; PARTICIPATES IN brain natriuretic peptide signaling pathw ay; ASSOCIATED WITH cardiac hypertrophy; hypertension; increased urine protein level; ASSOCIATED WITH acute kidney failure; Cardiomegaly; congestive heart failure; FOUND IN extracellular space; perinuclear region of cytoplasm; protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl | 5 | 163699955 | 163701314 | Rat | 498 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2786 | Hcrt | hypocretin neuropeptide precursor | ENCODES a protein that exhibits neuropeptide hormone activity; type 1 orexin receptor binding; type 2 orexin receptor binding; INVOLVED IN behavioral response to ethanol; drinking behavior; eating behavior; PARTICIPATES IN orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/ hypocretin signaling pathway via orexin/hypocretin receptor 2; orexin/hypocretin signaling pathway; ASSOCIATED WITH alcohol use disorder; hyperglycemia; Hyperphagia; FOUND IN neuronal dense core vesicle lumen; secretory granule; perinuclear region of cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 86190289 | 86191524 | Rat | 147 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 3579 | Rln1 | relaxin 1 | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of apoptotic process; regulation of cell population proliferation; ASSOCIATED WITH Hypertrophy (ortholog); FOUND IN extrac ellular region (inferred); INTERACTS WITH ammonium chloride; berberine; bisphenol A | 1 | 236493532 | 236496541 | Rat | 67 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620888 | Nucb2 | nucleobindin 2 | ENCODES a protein that exhibits G-protein alpha-subunit binding; guanyl-nucleotide exchange factor activity; tumor necrosis factor receptor binding; INVOLVED IN insulin metabolic process; negative regulation of appetite; negative regulation of cAMP/PKA signal transduction; ASSOCIATED WITH alcohol de pendence; obesity; type 2 diabetes mellitus; FOUND IN extracellular space; Golgi medial cisterna; cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 180185121 | 180221644 | Rat | 212 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308379 | Ctrc | chymotrypsin C | ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); proteolysis (ortholog); ASSOCIATED WITH chronic pancreatitis (ortholog); Hereditary Pancreatitis (ortholog); INTERACTS WITH 17be ta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 159430333 | 159439557 | Rat | 67 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62054 | Pdyn | prodynorphin | ENCODES a protein that exhibits opioid peptide activity (inferred); INVOLVED IN locomotion involved in locomotory behavior; response to ethanol; response to immobilization stress; ASSOCIATED WITH alcohol dependence; alcohol use disorder; alcohol withdrawal syndrome; FOUND IN axon terminus; dendritic spine; dense core granule; INTERACTS WITH (R,R)-tramadol; (S)-amphetamine; 1,3-dinitrobenzene | 3 | 137354161 | 137366503 | Rat | 288 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 3175 | Klk1b3 | kallikrein 1-related peptidase B3 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH hypertension; INTERACTS WITH 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil; bacitracin | 1 | 103845647 | 103849854 | Rat | 48 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2383 | Cort | cortistatin | ENCODES a protein that exhibits neuropeptide hormone activity; G protein-coupled receptor binding (ortholog); INVOLVED IN neuropeptide signaling pathway; regulation of circadian sleep/wake cycle, sleep; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH brain infarction; FOUND IN extracellular region (inferred); INTERACTS WITH (S)-nicotine; 2,4,6-trinitrobenzenesulfonic acid; 6-propyl-2-thiouracil | 5 | 164843682 | 164845796 | Rat | 70 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2184 | Avp | arginine vasopressin | ENCODES a protein that exhibits neuropeptide hormone activity; V1A vasopressin receptor binding; V1B vasopressin receptor binding; INVOLVED IN grooming behavior; locomotory behavior; maternal aggressive behavior; PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via recept or type 1; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH polyuria; ASSOCIATED WITH alcohol dependence; alcohol use disorder; alcohol withdrawal syndrome; FOUND IN dendrite; extracellular region; extracellular space; INTERACTS WITH (R)-noradrenaline; (S)-colchicine; (S)-nicotine | 3 | 138246544 | 138248522 | Rat | 341 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2532 | Edn1 | endothelin 1 | ENCODES a protein that exhibits endothelin A receptor binding; endothelin B receptor binding; cytokine activity (ortholog); INVOLVED IN artery smooth muscle contraction; cellular response to calcium ion; cellular response to fatty acid; PARTICIPATES IN inflammatory response pathway; endothelin signa ling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH adult respiratory distress syndrome; Albuminuria; aspiration pneumonia; FOUND IN basal part of cell; extracellular space; rough endoplasmic reticulum lumen; INTERACTS WITH (+)-catechin; (R)-noradrenaline; 1,3-dinitrobenzene | 17 | 22660799 | 22666687 | Rat | 1127 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2533 | Edn2 | endothelin 2 | ENCODES a protein that exhibits endothelin B receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN negative regulation of hormone secretion; ovarian follicle rupture; phospholipase C-activating G protein-coupled receptor signaling pathway; PARTICIPATES IN endothelin signaling pathway ; ASSOCIATED WITH myocardial infarction; Reperfusion Injury; Aortic Rupture (ortholog); FOUND IN extracellular space; INTERACTS WITH ammonium chloride; bis(2-ethylhexyl) phthalate; bisphenol A | 5 | 139036576 | 139042074 | Rat | 178 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 628842 | Tac4 | tachykinin precursor 4 | ENCODES a protein that exhibits receptor ligand activity (ortholog); signaling receptor binding (ortholog); substance K receptor binding (ortholog); INVOLVED IN detection of temperature stimulus involved in sensory perception of pain; positive regulation of sensory perception of pain; negative regul ation of sensory perception of pain (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN extracellular space; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide | 10 | 80704640 | 80712972 | Rat | 73 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1307076 | Cntnap2 | contactin associated protein 2 | ENCODES a protein that exhibits protease binding; transmembrane transporter binding; enzyme binding (ortholog); INVOLVED IN prepulse inhibition; startle response; action potential initiation (ortholog); ASSOCIATED WITH abnormal auditory brainstem response; abnor mal habituation; abnormal prepulse inhibition; ASSOCIATED WITH autism spectrum disorder; epilepsy; articulation disorder (ortholog); FOUND IN axolemma; dendrite; GABA-ergic synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 4 | 75109358 | 77366258 | Rat | 301 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2272 | Cartpt | CART prepropeptide | ENCODES a protein that exhibits neuropeptide hormone activity (inferred); INVOLVED IN adult feeding behavior; behavioral response to cocaine; cAMP biosynthetic process; ASSOCIATED WITH amnestic disorder; amphetamine abuse; cerebral infarction; FOUND IN cytoplasm; extracellular space; neuronal cell b ody; INTERACTS WITH (3,4-dihydroxyphenyl)acetic acid; (S)-nicotine; 17beta-estradiol | 2 | 32989215 | 32991794 | Rat | 238 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 620983 | Oprpn | opiorphin prepropeptide | ENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog); peptidase inhibitor activity (ortholog); INVOLVED IN regulation of sensory perception of pain (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; C60 fullerene | 14 | 19986575 | 20001589 | Rat | 25 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 61954 | Gal | galanin and GMAP prepropeptide | ENCODES a protein that exhibits galanin receptor activity (ortholog); neuropeptide hormone activity (ortholog); type 1 galanin receptor binding (ortholog); INVOLVED IN behavioral response to ethanol; drinking behavior; feeding behavior; ASSOCIATED WITH alcohol use disorder; alcohol withdrawal syndro me; brain ischemia; FOUND IN secretory granule; extracellular space (ortholog); neuron projection terminus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 210079709 | 210084572 | Rat | 288 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 632283 | Ghrl | ghrelin and obestatin prepropeptide | ENCODES a protein that exhibits G protein-coupled receptor binding; ghrelin receptor binding; growth hormone-releasing hormone activity; INVOLVED IN G protein-coupled receptor signaling pathway; gastric acid secretion; negative regulation of apoptotic process; PARTICIPATES IN ghrelin system pathway; ASSOCIATED WITH Cardiac Fibrosis; Experimental Autoimmune Encephalomyelitis; Experimental Diabetes Mellitus; FOUND IN glutamatergic synapse; Schaffer collateral - CA1 synapse; axon (ortholog); INTERACTS WITH 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | 4 | 148421315 | 148431128 | Rat | 297 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 3238 | Oxt | oxytocin/neurophysin I prepropeptide | ENCODES a protein that exhibits neuropeptide hormone activity; oxytocin receptor binding; INVOLVED IN drinking behavior; eating behavior; female pregnancy; PARTICIPATES IN oxytocin signaling pathway; ASSOCIATED WITH amphetamine abuse; Burns; Dehydration; FOUND IN extracellular space; neuronal dense core vesicle; secretory granule; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-D | 3 | 138235754 | 138236594 | Rat | 217 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1308862 | Sec62 | SEC62 preprotein translocation factor | INVOLVED IN post-translational protein targeting to endoplasmic reticulum membrane (ortholog); post-translational protein targeting to membrane, translocation (ortholog); reticulophagy (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN membrane (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aldehydo-D-glucose | 2 | 114499317 | 114526705 | Rat | 129 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 708513 | Npb | neuropeptide B | ENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); FOUND IN anaphase-promoting complex (inferred); extracellular region (inferred); nucleolus (inferred); INTERA CTS WITH 6-propyl-2-thiouracil; acrylamide; alpha-Zearalanol | 10 | 106382307 | 106385566 | Rat | 65 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 727858 | Npw | neuropeptide W | ENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN G protein-coupled receptor signaling pathway; feeding behavior (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 14184819 | 14186155 | Rat | 40 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 68946 | Penk | proenkephalin | ENCODES a protein that exhibits opioid peptide activity; receptor ligand activity (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to cAMP; cellular response to oxidative stress; ASSOCIATED WITH alcohol use disorder; Anhedonia; Catalepsy; FOUND IN axon; axon terminus; cell b ody fiber; INTERACTS WITH (S)-amphetamine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 5 | 21981381 | 21987074 | Rat | 289 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 708585 | 1810009J06Rikl | RIKEN cDNA 1810009J06 gene like | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN digestion (inferred); proteolysis (inferred); FOUND IN extracellular region (inferred) | 4 | 70781783 | 70792997 | Rat | 13 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2024 | Acr | acrosin | ENCODES a protein that exhibits amidase activity (ortholog); D-mannose binding (ortholog); fucose binding (ortholog); INVOLVED IN acrosome matrix dispersal; penetration of zona pellucida; protein catabolic process; ASSOCIATED WITH decreased litter size; impaired acrosome reaction; ASSOCIATED WITH sp ermatogenic failure 87 (ortholog); FOUND IN acrosomal vesicle; Golgi-associated vesicle; protein-containing complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; flavonoids | 7 | 122517910 | 122524110 | Rat | 83 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2130 | Apoa1 | apolipoprotein A1 | ENCODES a protein that exhibits amyloid-beta binding; cholesterol transfer activity; lipase inhibitor activity; INVOLVED IN animal organ regeneration; cholesterol transport; negative regulation of lipase activity; PARTICIPATES IN altered lipoprotein metabolic pathway; forkhead class A signaling path way; lipoprotein metabolic pathway; ASSOCIATED WITH arteriosclerosis; Endotoxemia; Experimental Diabetes Mellitus; FOUND IN cell surface; discoidal high-density lipoprotein particle; extracellular space; INTERACTS WITH (R,R,R)-alpha-tocopherol; 1-naphthyl isothiocyanate; 2,2,2-tetramine | 8 | 55423945 | 55425729 | Rat | 683 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 621512 | Gdf10 | growth differentiation factor 10 | ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); INVOLVED IN cerebellum development; osteoblast differentiation; ovulation cycle; ASSOCIATED WITH Arterial Occlusive Diseases (ortholog); Breast Neoplasms (ortholog); Mesothelioma (ortholog); FOUND IN ext racellular space; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 16 | 9243434 | 9256788 | Rat | 141 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2917 | Insr | insulin receptor | ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; cargo receptor activity; insulin binding; INVOLVED IN amyloid-beta clearance; cellular response to zinc ion starvation; cerebellum development; PARTICIPATES IN altered leptin system pathway; insulin signaling pathwa y; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH decreased body weight; increased circulating glucose level; increased circulating insulin level; ASSOCIATED WITH Alzheimer's disease; chronic kidney disease; diabetic neuropathy; FOUND IN cell body; dendrite; dendrite membrane; INTERACTS WITH (+)-catechin; (3,4-dihydroxyphenyl)acetic acid; (S)-nicotine | 12 | 5991135 | 6129275 | Rat | 653 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 61998 | Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | ENCODES a protein that exhibits protein-containing complex binding; enzyme binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription; negative regulation of G protein-coupled receptor signaling pathway (ortholog); negative regulation o f protein import into nucleus (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH brain ischemia; Experimental Seizures; systemic lupus erythematosus (ortholog); FOUND IN protein-containing complex; transcription repressor complex; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 3 | 173078904 | 173101508 | Rat | 214 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628634 | Prlh | prolactin releasing hormone | ENCODES a protein that exhibits neuropeptide hormone activity; prolactin-releasing peptide receptor binding; INVOLVED IN feeding behavior; G protein-coupled receptor signaling pathway; reduction of food intake in response to dietary excess; PARTICIPATES IN obesity pathway; ASSOCIATED WITH obesity; F OUND IN cytoplasm; INTERACTS WITH ammonium chloride; bisphenol A; diethylstilbestrol | 9 | 98991628 | 98996515 | Rat | 42 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1593461 | Klk5 | kallikrein related-peptidase 5 | ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN antibacterial peptide biosynthetic process (ortholog); positive regulation of G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (orthol og); FOUND IN epidermal lamellar body (ortholog); extracellular space (ortholog); INTERACTS WITH N,N-diethyl-m-toluamide; permethrin; (S)-nicotine (ortholog) | 1 | 103432743 | 103442011 | Rat | 57 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1566350 | Cdh12 | cadherin 12 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane ( inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; atrazine | 2 | 72201859 | 73436039 | Rat | 69 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 3862 | Timm17a | translocase of inner mitochondrial membrane 17A | ENCODES a protein that exhibits enzyme binding; INVOLVED IN positive regulation of protein processing; PARTICIPATES IN presequence pathway of mitochondrial protein import; FOUND IN mitochondrial inner membrane; mitochondrion (ortholog); TIM23 mitochondrial import inner membrane translocase complex ( ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 13 | 49282918 | 49296363 | Rat | 123 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 11568647 | Cntnap2em1Sage | contactin associated protein-like 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs | ASSOCIATED WITH abnormal auditory brainstem response; abnormal habituation; abnormal prepulse inhibition; ASSOCIATED WITH autism spectrum disorder; epilepsy | | | | Rat | 11 | description | gene, allele |
| 2290090 | Nrg1Tn(sb-T2/Bart3)2.183Mcwi | neuregulin 1; transposon insertion 2.183, Medical College of Wisconsin | ASSOCIATED WITH abnormal habituation; decreased locomotor activity; decreased prepulse inhibition; ASSOCIATED WITH stress-related disorder | | | | Rat | 8 | description | gene, allele |
| 14694849 | Pvalbem1(flpo)Berke | parvalbumin; CRISPR/Cas9 induced flpo knock in mutant1, Berke | A double-stranded DNA plasmid donor was synthesized to introduce self-cleaving peptide 2A (P2A),followed by Flpo recombinase,and the V5 peptide tag (GKPIPNPLLGLDST) before the termination codon in exon 5 of rat Parvalbumin. (ref:bioRxiv preprint first posted onl ine Aug. 7, 2018; doi: http://dx.doi.org/10.1101/386474. ) | | | | Rat | | description | gene, allele |
| 1303022 | Tomm40 | translocase of outer mitochondrial membrane 40 | ENCODES a protein that exhibits monoatomic cation channel activity; preprotein binding; protein transmembrane transporter activity; INVOLVED IN positive regulation of apoptotic process; protein insertion into mitochondrial membrane; protein targeting to mitochon drion; PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import; intermembrane space assembly pathway of mitochondrial protein import; ASSOCIATED WITH Experimental Diabetes Mellitus; Alzheimer's disease (ortholog); Animal Disease Models (ortholog); FOUND IN mitochondrial outer membrane; mitochondrial outer membrane translocase complex; mitochondrion; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 88486745 | 88498833 | Rat | 152 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562006 | Tomm40l | translocase of outer mitochondrial membrane 40 like | ENCODES a protein that exhibits mitochondrion targeting sequence binding; preprotein binding; INVOLVED IN protein import into mitochondrial matrix (inferred); protein transport (inferred); transmembrane transport (inferred); FOUND IN mitochondrial outer membrane translocase complex; mitochondrion (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acetamide | 13 | 86169160 | 86174121 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359376 | Kng1 | kininogen 1 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN negative regulation of blood coagulation (ortholog); negative regulation of cell adhesion (ortholog); negative regulation of prot eolysis (ortholog); PARTICIPATES IN kallikrein-kinin cascade pathway; kinin signaling pathway; syndecan signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm; Kininogen Deficiency, High Molecular Weight and Low Molecular Weight; acquired angioedema (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 1-octadec-9-enoylglycero-3-phosphate | 11 | 91317354 | 91340148 | Rat | 303 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2870 | Igf2 | insulin-like growth factor 2 | ENCODES a protein that exhibits growth factor activity (ortholog); insulin receptor binding (ortholog); insulin-like growth factor receptor binding (ortholog); INVOLVED IN cellular response to mechanical stimulus; female pregnancy; memory; PARTICIPATES IN insulin-like growth factor signaling pathway ; ASSOCIATED WITH alcohol-associated liver disease; alcoholic neuropathy; Alzheimer's disease; FOUND IN extracellular space; INTERACTS WITH (S)-nicotine; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate | 1 | 207243873 | 207261263 | Rat | 482 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1559447 | Pth2 | parathyroid hormone 2 | INVOLVED IN neuropeptide signaling pathway (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; Cuprizon; trichloroethene | 1 | 104802983 | 104803632 | Rat | 22 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359122 | Nms | neuromedin S | ENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN locomotor rhythm; neuropeptide signaling pathway; FOUND IN extracellular region (inferred); INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog); 1,2-dichloroethane (ortholog); 2,2',4,4',5,5'-hexachlor obiphenyl (ortholog) | 9 | 48665398 | 48676461 | Rat | 15 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68388 | Nmu | neuromedin U | ENCODES a protein that exhibits neuromedin U receptor binding; type 1 neuromedin U receptor binding; type 2 neuromedin U receptor binding; INVOLVED IN eating behavior; energy homeostasis; gastric acid secretion; ASSOCIATED WITH obesity; FOUND IN terminal bouton; INTERACTS WITH 6-propyl-2-thiouracil; 8-Br-cAMP; amitrole | 14 | 32198789 | 32226397 | Rat | 163 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560118 | Adamts18 | ADAM metallopeptidase with thrombospondin type 1 motif, 18 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN eye development (ortholog); negative regulation of platelet aggregation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 19 | 58596095 | 58749239 | Rat | 73 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |