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ONTOLOGY REPORT - ANNOTATIONS

Term:sarcomere organization
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Accession:GO:0045214 term browser browse the term
Definition:The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms:exact_synonym: sarcomere alignment;   sarcomere organisation
 alt_id: GO:0006938


show annotations for term's descendants           Sort by:
sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15194427)		 Ensembl
RGD		 PMID:15194427 GO_REF:0000107 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actg1l1 actin, gamma 1 like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:72,977,767...72,979,691
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actn1 actinin, alpha 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IMP PMID:17921333 BHF-UCL PMID:17921333 RGD:2302083 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Capn3 calpain 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:3046866 (PMID:15138196)		 UniProt
Ensembl
RGD		 PMID:15138196 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Casq1 calsequestrin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306707|PMID:22049211)		 UniProt
RGD		 PMID:22049211 GO_REF:0000024 MGI:5306707 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (MGI:4453101|PMID:19920148) RGD PMID:19920148 MGI:4453101 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267 		JBrowse link
G Cfl2 cofilin 2 acts_upstream_of_or_within ISO MGI:2182095|MGI:5316051|MGI:5316057 (PMID:22343409) RGD PMID:22343409 NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 PMID:19706596
UniProtKB:F1LQJ2 (PMID:19706596)
GO_REF:0000033		 RGD
GO_Central		 PMID:19706596 PMID:19706596 GO_REF:0000033, RGD:8554207 NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796 		JBrowse link
G Flnc filamin C involved_in ISO
IEA
ISS		 (PMID:34405687)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:34405687 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154539 (PMID:9004034)		 Ensembl
RGD		 PMID:9004034 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Krt19 keratin 19 involved_in ISO (PMID:16000376) RGD PMID:16000376 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt8 keratin 8 involved_in IDA PMID:15247274 UniProt PMID:15247274 RGD:1600063 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Ldb3 LIM domain binding 3 acts_upstream_of_or_within ISO MGI:2652058 (PMID:11696561) RGD PMID:11696561 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532 		JBrowse link
G Lmod2 leiomodin 2 involved_in ISO
IEA
IMP		 (PMID:18403713)
GO_REF:0000107
(MGI:5787841|PMID:27274810)		 RGD
Ensembl		 PMID:18403713 PMID:27274810 PMID:18403713 GO_REF:0000107 MGI:5787841, RGD:11344939 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Mybpc2 myosin binding protein C2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,994,121...95,017,584
Ensembl chr 1:94,994,104...95,017,584 		JBrowse link
G Mybpc3 myosin binding protein C3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2654420|MGI:3606208 (PMID:16224063), (PMID:16380103), (PMID:17075052)		 GO_Central
RGD		 PMID:16224063 PMID:16380103 PMID:17075052 GO_REF:0000033 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405 		JBrowse link
G Mybph myosin binding protein H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893 		JBrowse link
G Myh6 myosin heavy chain 6 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3652543 (PMID:8878443)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:8878443 GO_REF:0000033 GO_REF:0000107 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myh7 myosin heavy chain 7 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IMP
IBA
ISO		 PMID:18202317
GO_REF:0000033
(MGI:3841874|PMID:18202317)		 GO_Central
RGD		 PMID:18202317 PMID:18202317 GO_REF:0000033 MGI:3841874, RGD:8554765 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Myom1 myomesin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344 		JBrowse link
G Myom2 myomesin 2 involved_in ISO
IBA		 (PMID:33033063)
GO_REF:0000033		 RGD
GO_Central		 PMID:33033063 GO_REF:0000033 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Myom3 myomesin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274 		JBrowse link
G Myoz1 myozenin 1 involved_in ISO (MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:3831256 NCBI chr15:3,644,333...3,651,584
Ensembl chr15:3,644,368...3,652,884 		JBrowse link
G Myoz2 myozenin 2 involved_in ISO (MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:3513659 NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221 		JBrowse link
G Mypn myopalladin involved_in ISO (PMID:11309420) RGD PMID:11309420 NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443 		JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 acts_upstream_of_or_within ISO MGI:3043523 (PMID:14960280) RGD PMID:14960280 NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380 		JBrowse link
G Plec plectin involved_in IEA
ISO		 GO_REF:0000107
(PMID:24487589)		 Ensembl
RGD		 PMID:24487589 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO MGI:2182091|MGI:3512112 (PMID:18316483) RGD PMID:18316483 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5298278|PMID:21884692) RGD PMID:21884692 MGI:5298278 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3522214 (PMID:15569937) RGD PMID:15569937 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Synpo2l synaptopodin 2-like involved_in ISO (MGI:6102963|PMID:29206857) RGD PMID:29206857 MGI:6102963 NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) RGD PMID:9817758 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000118
MGI:3692448|MGI:3692450|MGI:3692451 (PMID:10449439)
GO_REF:0000033		 TreeGrafter
RGD
GO_Central		 PMID:10449439 GO_REF:0000033 GO_REF:0000118 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tnnt3 troponin T3, fast skeletal type involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:197,652,535...197,669,736
Ensembl chr 1:197,652,431...197,669,535 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO
IEA		 (PMID:11273725)
GO_REF:0000107		 RGD
Ensembl		 PMID:11273725 GO_REF:0000107 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within		 IDA
ISO		 (PMID:11846417), (PMID:9804419), (PMID:9817758)
MGI:3654306 (PMID:16702235), (PMID:17360664)		 RGD PMID:9804419 PMID:9817758 PMID:11846417 PMID:16702235 PMID:17360664 More... RGD:634444 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741 		JBrowse link
G Wdr1 WD repeat domain 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:24840128)		 GO_Central
RGD		 PMID:24840128 GO_REF:0000033 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766 		JBrowse link
G Xirp1 xin actin-binding repeat containing 1 acts_upstream_of_or_within ISO MGI:3521795 (PMID:17766470) RGD PMID:17766470 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349 		JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:24777478 RGD:13204833 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
positive regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333 GO_REF:0000107 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IDA PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Prkd1 protein kinase D1 IMP RGD PMID:16648482 RGD:243065275 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:3830437 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5308772|PMID:20139090)		 UniProt
RGD		 PMID:20139090 GO_REF:0000024 MGI:5308772 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 acts_upstream_of_or_within ISO MGI:1097717|MGI:1861447 (PMID:17392382) RGD PMID:17392382 NCBI chr 9:38,773,234...38,778,705
Ensembl chr 9:38,773,240...38,779,839 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (PMID:17322895) RGD PMID:17322895 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (PMID:17875930) RGD PMID:17875930 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure formation involved in morphogenesis 1379
        cellular component assembly involved in morphogenesis 154
          myofibril assembly 79
            sarcomere organization 55
              negative regulation of sarcomere organization 2
              positive regulation of sarcomere organization 6
              regulation of sarcomere organization + 12
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular component organization or biogenesis 7292
        cellular component organization 6982
          organelle organization 3887
            cytoskeleton organization 1643
              actin cytoskeleton organization 786
                actomyosin structure organization 230
                  myofibril assembly 79
                    sarcomere organization 55
                      negative regulation of sarcomere organization 2
                      positive regulation of sarcomere organization 6
                      regulation of sarcomere organization + 12
paths to the root