Gene: Ttn (titin) Rattus norvegicus
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Symbol: Ttn
Name: titin
Description: ENCODES a protein that exhibits actin filament binding (ortholog); actinin binding (ortholog); ankyrin binding (ortholog); INVOLVED IN sarcomere organization; adult heart development (ortholog); cardiac muscle contraction (ortholog); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; ASSOCIATED WITH abnormal cardiac muscle contractility; decreased cardiac muscle relaxation; decreased cardiac stroke volume; ASSOCIATED WITH Myocardial Infarction; myocardial infarction; Myocardial Ischemia; FOUND IN I band; myofibril; A band (ortholog); INTERACTS WITH 3,3',5-triiodo-L-thyronine; acetylleucyl-leucyl-norleucinal; acrylamide
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: titin; titin protein homolog
Orthologs:
Homo sapiens (human) : TTN (titin)  HGNC  AGR
Mus musculus (house mouse) : Ttn (titin)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ttn (titin)
Pan paniscus (bonobo/pygmy chimpanzee) : TTN (titin)
Canis lupus familiaris (dog) : TTN (titin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttn (titin)
more info ...
Allele / Splice: Ttnem1Sage   Ttnem2Sage  
Genetic Models: F344-Ttnem2Sage F344-Ttnem1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Celera361,137,881 - 61,409,292 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models

Sequence

Nucleotide Sequences