Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of double-strand break repair
go back to main search page
Accession:GO:2000781 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of double-strand break repair.


show annotations for term's descendants           Sort by:
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:23797032) RGD PMID:23797032 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550 		JBrowse link
G Fmn2 formin 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)		 RGD
Ensembl		 PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISS
ISO		 GO_REF:0000024
(MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731)		 UniProt
RGD		 PMID:29125140 PMID:33115731 GO_REF:0000024 MGI:6467697 MGI:6716977 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase involved_in ISO
IEA		 (PMID:24147153)
GO_REF:0000107		 RGD
Ensembl		 PMID:24147153 GO_REF:0000107 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) RGD PMID:29125140 MGI:6467697 NCBI chr 8:79,223,388...79,224,554
Ensembl chr 8:79,223,375...79,224,541 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:32538779) RGD PMID:32538779 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23911928), (PMID:31995034), (PMID:32538779)
(MGI:7258357|PMID:31002797)		 RGD PMID:23911928 PMID:31002797 PMID:31995034 PMID:32538779 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in ISO
IBA		 (PMID:25931565)
GO_REF:0000033		 RGD
GO_Central		 PMID:25931565 GO_REF:0000033 NCBI chr 1:243,782,786...243,845,418
Ensembl chr 1:243,782,246...243,845,250 		JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23509288) RGD PMID:23509288 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600 		JBrowse link
G Spire1 spire-type actin nucleation factor 1 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr18:61,041,914...61,171,670
Ensembl chr18:61,041,290...61,171,899 		JBrowse link
G Spire2 spire-type actin nucleation factor 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr19:51,373,368...51,411,920
Ensembl chr19:51,373,228...51,411,920 		JBrowse link
G Timeless timeless circadian regulator involved_in ISO
ISS		 (PMID:23797032)
GO_REF:0000024		 RGD
UniProt		 PMID:23797032 GO_REF:0000024 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27715493)		 UniProt
RGD		 PMID:27715493 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Zcwpw1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) RGD PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr12:18,880,625...18,910,713
Ensembl chr12:18,880,633...18,910,711 		JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO
IEA		 (PMID:27153538)
GO_REF:0000107		 RGD
Ensembl		 PMID:27153538 GO_REF:0000107 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actl6a actin-like 6A involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr2 actin related protein 2 involved_in ISO
IEA
ISS		 (PMID:29925947)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29925947 GO_REF:0000024 GO_REF:0000107 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Arid2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) RGD PMID:28381560 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2448558 (PMID:25520194) RGD PMID:25520194 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Brd8 bromodomain containing 8 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884 		JBrowse link
G Crebbp CREB binding protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:38128537)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:38128537 GO_REF:0000024 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 5:131,143,726...131,151,760
Ensembl chr 5:131,143,729...131,151,742 		JBrowse link
G Ep400 E1A binding protein p400 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Epc2 enhancer of polycomb homolog 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1328362 (PMID:25520194)		 GO_Central
RGD		 PMID:25520194 GO_REF:0000033 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Fus Fus RNA binding protein involved_in ISO (PMID:10567410) RGD PMID:10567410 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414 		JBrowse link
G Hdgfl2 HDGF like 2 involved_in ISO
IEA
ISS		 (PMID:26721387)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26721387 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186 		JBrowse link
G Helq helicase, POLQ-like involved_in ISO (MGI:5547892|PMID:24005329) RGD PMID:24005329 MGI:5547892 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Ing3 inhibitor of growth family, member 3 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27153538), (PMID:32832608)		 UniProt
Ensembl
RGD		 PMID:27153538 PMID:32832608 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISO
ISS		 (PMID:31609975)
(MGI:6716962|PMID:25936915)
GO_REF:0000024		 RGD
UniProt		 PMID:25936915 PMID:31609975 GO_REF:0000024 MGI:6716962 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248 		JBrowse link
G Mbtd1 mbt domain containing 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr10:78,839,140...78,895,413
Ensembl chr10:78,839,036...78,893,720 		JBrowse link
G Meaf6 MYST/Esa1-associated factor 6 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 5:137,344,681...137,369,703
Ensembl chr 5:137,344,380...137,370,014 		JBrowse link
G Morf4l1 mortality factor 4 like 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519 		JBrowse link
G Morf4l2 mortality factor 4 like 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728 		JBrowse link
G Mrgbp MRG domain binding protein involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 3:167,697,129...167,700,592
Ensembl chr 3:167,697,185...167,700,592 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469 		JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) RGD PMID:29955025 MGI:6272426 NCBI chr 8:79,223,388...79,224,554
Ensembl chr 8:79,223,375...79,224,541 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000024		 RGD
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30952868) RGD PMID:30952868 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 involved_in ISO (PMID:32832608) RGD PMID:32832608 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15741314), (PMID:29651020)		 UniProt
RGD		 PMID:15741314 PMID:29651020 GO_REF:0000024 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) RGD PMID:17996710 PMID:17996711 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Rnf126 ring finger protein 126 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36563124)		 Ensembl
RGD		 PMID:36563124 GO_REF:0000107 NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23115235)		 UniProt
RGD		 PMID:23115235 GO_REF:0000024 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Skp2 S-phase kinase associated protein 2 involved_in ISO (PMID:22464731)
(MGI:5438910|PMID:22464731)		 RGD PMID:22464731 MGI:5438910 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Timeless timeless circadian regulator involved_in ISO
IEA
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Trrap transformation/transcription domain-associated protein involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674 		JBrowse link
G Vps72 vacuolar protein sorting 72 homolog involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 2:182,678,594...182,690,185
Ensembl chr 2:182,678,609...182,690,182 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:14,405,105...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) RGD PMID:27239033 PMID:27463890 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISO
ISS		 (PMID:25512560)
GO_REF:0000024		 RGD
UniProt		 PMID:25512560 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Yeats4 YEATS domain containing 4 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 7:52,858,313...52,865,454
Ensembl chr 7:52,858,305...52,865,635 		JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase involved_in ISO
ISS		 (PMID:26237645)
GO_REF:0000024		 RGD
UniProt		 PMID:26237645 GO_REF:0000024 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO		 GO_REF:0000024
(PMID:28114273)		 UniProt
RGD		 PMID:28114273 GO_REF:0000024 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS		 (PMID:28114273)
GO_REF:0000024		 RGD
UniProt		 PMID:28114273 GO_REF:0000024 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (PMID:24598253) RGD PMID:24598253 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:12032095) RGD PMID:12032095 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:26237645) RGD PMID:26237645 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:28241136)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)		 RGD PMID:23306437 PMID:23333305 PMID:28241136 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:20620605), (PMID:21491884) RGD PMID:20620605 PMID:21491884 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA		 (PMID:29656893)
GO_REF:0000033		 RGD
GO_Central		 PMID:29656893 GO_REF:0000033 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893), (PMID:29789392) RGD PMID:29656893 PMID:29789392 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665 		JBrowse link
G Top2b DNA topoisomerase II beta IMP RGD PMID:22019940 RGD:13432143 NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25512560)		 UniProt
RGD		 PMID:25512560 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    positive regulation of biological process 6651
      positive regulation of response to stimulus 2486
        positive regulation of DNA repair 116
          positive regulation of double-strand break repair 72
            positive regulation of double-strand break repair via homologous recombination 43
            positive regulation of double-strand break repair via nonhomologous end joining 16
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      organic substance metabolic process 10970
        organic cyclic compound metabolic process 6031
          nucleobase-containing compound metabolic process 5524
            nucleic acid metabolic process 4949
              DNA metabolic process 949
                regulation of DNA metabolic process 453
                  positive regulation of DNA metabolic process 277
                    positive regulation of DNA repair 116
                      positive regulation of double-strand break repair 72
                        positive regulation of double-strand break repair via homologous recombination 43
                        positive regulation of double-strand break repair via nonhomologous end joining 16
paths to the root