Epc1 (enhancer of polycomb homolog 1)

Gene: Epc1 (enhancer of polycomb homolog 1) Rattus norvegicus

Analyze

Symbol:

Epc1

Name:

enhancer of polycomb homolog 1

RGD ID:

2324280

Description:

Predicted to enable chromatin-protein adaptor activity and enzyme-substrate adaptor activity. Involved in vascular associated smooth muscle cell differentiation. Predicted to be located in nuclear body; nuclear membrane; and nucleolus. Predicted to be part of NuA4 histone acetyltransferase complex; nucleosome; and piccolo histone acetyltransferase complex. Predicted to be active in site of double-strand break. Orthologous to human EPC1 (enhancer of polycomb homolog 1); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

enhancer of polycomb homolog 1 (Drosophila); LOC100362678; LOC307042

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPC1 (enhancer of polycomb homolog 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Epc1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Epc1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EPC1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPC1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Epc1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPC1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPC1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Epc1 (enhancer of polycomb homolog 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EPC1 (enhancer of polycomb homolog 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Epc1 (enhancer of polycomb homolog 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epc1a (enhancer of polycomb homolog 1 (Drosophila) a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epc1b (enhancer of polycomb homolog 1 (Drosophila) b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	EPL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	E(Pc)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	epc-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	epc1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	59,198,513 - 59,289,535 (-)	NCBI		GRCr8
mRatBN7.2	17	54,503,358 - 54,594,444 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	54,503,358 - 54,594,425 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	57,670,117 - 57,762,113 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	61,673,219 - 61,765,221 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	55,840,859 - 55,932,853 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	57,303,968 - 57,394,975 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	57,304,933 - 57,394,985 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	55,332,012 - 55,423,030 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	63,040,151 - 63,131,954 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	63,050,987 - 63,115,013 (-)	NCBI
Celera	17	50,484,141 - 50,575,159 (-)	NCBI		Celera
Cytogenetic Map	17	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neointima (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-fluoro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

amiodarone (ISO)

antirheumatic drug (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

entinostat (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hydralazine (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

leflunomide (ISO)

methyl methanesulfonate (ISO)

nitrofen (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

resveratrol (ISO)

sodium arsenite (ISO)

tetrachloromethane (ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

double-strand break repair via homologous recombination (ISO)

negative regulation of DNA-templated transcription (ISO)

negative regulation of gene expression, epigenetic (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of double-strand break repair via homologous recombination (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of cell cycle (ISO)

regulation of transcription by RNA polymerase II (IBA)

sperm DNA condensation (ISO)

spermatid development (ISO)

vascular associated smooth muscle cell differentiation (IEP)

Cellular Component

NuA4 histone acetyltransferase complex (ISO)

nuclear body (ISO)

nuclear membrane (ISO)

nucleolus (ISO)

nucleoplasm (ISO)

nucleosome (ISO)

nucleus (ISO)

piccolo histone acetyltransferase complex (IBA,ISO)

site of double-strand break (ISO)

Molecular Function

chromatin-protein adaptor activity (ISO)

enzyme-substrate adaptor activity (ISO)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

INO80 family mediated chromatin remodeling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Enhancer of polycomb1 lessens neointima formation by potentiation of myocardin-induced smooth muscle differentiation.	Joung H, etal., Atherosclerosis. 2012 May;222(1):84-91. doi: 10.1016/j.atherosclerosis.2012.02.015. Epub 2012 Feb 18.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation
5.	The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics.	Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.

Additional References at PubMed

PMID:10976108	PMID:12477932	PMID:14966270	PMID:15632090	PMID:17192267	PMID:19359245

Genomics

Comparative Map Data

Epc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	59,198,513 - 59,289,535 (-)	NCBI		GRCr8
mRatBN7.2	17	54,503,358 - 54,594,444 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	54,503,358 - 54,594,425 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	57,670,117 - 57,762,113 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	61,673,219 - 61,765,221 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	55,840,859 - 55,932,853 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	57,303,968 - 57,394,975 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	57,304,933 - 57,394,985 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	55,332,012 - 55,423,030 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	63,040,151 - 63,131,954 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	63,050,987 - 63,115,013 (-)	NCBI
Celera	17	50,484,141 - 50,575,159 (-)	NCBI		Celera
Cytogenetic Map	17	q12.1	NCBI

EPC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	32,267,751 - 32,378,769 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	32,267,751 - 32,378,798 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	32,556,679 - 32,667,697 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	32,597,865 - 32,676,119 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	32,597,864 - 32,676,119	NCBI
Celera	10	32,323,085 - 32,401,333 (-)	NCBI		Celera
Cytogenetic Map	10	p11.22	NCBI
HuRef	10	32,276,952 - 32,387,816 (-)	NCBI		HuRef
CHM1_1	10	32,558,317 - 32,669,300 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	32,296,867 - 32,407,873 (-)	NCBI		T2T-CHM13v2.0

Epc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	6,435,951 - 6,516,108 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	6,435,951 - 6,516,108 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	6,435,951 - 6,516,108 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	6,435,951 - 6,516,108 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	6,435,949 - 6,516,085 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	6,435,949 - 6,516,085 (-)	NCBI		MGSCv36	mm8
Celera	18	6,483,184 - 6,569,258 (-)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI
cM Map	18	4.48	NCBI

Epc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	23,817,254 - 23,909,946 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	23,819,261 - 23,910,279 (-)	NCBI	ChiLan1.0	ChiLan1.0

EPC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	44,918,832 - 45,029,617 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	44,924,971 - 45,034,770 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	32,398,557 - 32,509,146 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	32,985,456 - 33,095,070 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	32,985,456 - 33,095,070 (-)	Ensembl	panpan1.1		panPan2

EPC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	14,566,177 - 14,659,774 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	14,565,560 - 14,659,353 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	12,054,448 - 12,148,508 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	12,801,929 - 12,896,656 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	12,827,078 - 12,895,505 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	12,267,471 - 12,337,031 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	12,133,446 - 12,227,913 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	12,407,208 - 12,501,657 (+)	NCBI		UU_Cfam_GSD_1.0

Epc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	11,467,190 - 11,551,016 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936574	964,619 - 1,050,571 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936574	966,655 - 1,050,537 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	42,836,047 - 42,946,857 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	42,835,280 - 42,946,859 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	47,431,316 - 47,572,044 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	31,586,402 - 31,698,876 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	31,585,246 - 31,665,592 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	40,587,401 - 40,700,708 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Epc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624805	4,651,051 - 4,756,899 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624805	4,653,730 - 4,684,211 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Epc1
592 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	130
Count of miRNA genes:	110
Interacting mature miRNAs:	117
Transcripts:	ENSRNOT00000019968
Prediction methods:	Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	60781592	Rat
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	69599340	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	69599340	Rat
1354596	Bw32	Body weight QTL 32	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	17	4299130	60781592	Rat
1354630	Cm34	Cardiac mass QTL 34	8.7		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	4299130	69599340	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	4299130	69599340	Rat
1354651	Lmblg2	Limb length QTL 2	6		tibia length (VT:0004357)	tibia length (CMO:0000450)	17	4299130	69599340	Rat
1331765	Hrtrt15	Heart rate QTL 15	4.094		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	17	15330613	55836425	Rat
1354640	Scl32	Serum cholesterol level QTL 32	5.4		blood HDL cholesterol amount (VT:0000184)	blood high density lipoprotein cholesterol level (CMO:0000052)	17	15781592	60781592	Rat
1354659	Scl68	Serum cholesterol level QTL 68	3.9		blood VLDL cholesterol amount (VT:0005144)	blood very low density lipoprotein cholesterol level (CMO:0000648)	17	15781592	60781592	Rat
7394837	Memor18	Memory QTL 18			exploratory behavior trait (VT:0010471)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	17	18640182	63640182	Rat
1354628	Stl13	Serum triglyceride level QTL 13	3.8		blood triglyceride amount (VT:0002644)	blood triglyceride level (CMO:0000118)	17	21293039	60781592	Rat
61394	Bp8	Blood pressure QTL 8	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	23080567	59555013	Rat
7488966	Bp370	Blood pressure QTL 370		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	23653184	57246843	Rat
12903978	Cm118	Cardiac mass QTL 118		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	23653184	68653184	Rat
12903979	Cm119	Cardiac mass QTL 119		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	23653184	68653184	Rat
12903980	Cm120	Cardiac mass QTL 120		0.002	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	17	23653184	68653184	Rat
12903981	Am17	Aortic mass QTL 17		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	17	23653184	68653184	Rat
1559055	Bp278	Blood pressure QTL 278		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	23653184	68653184	Rat
12903982	Kidm70	Kidney mass QTL 70		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	23653184	70974005	Rat
1354619	Bp242	Blood pressure QTL 242	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	24599340	69599340	Rat
1581512	Cm55	Cardiac mass QTL 55	2.8	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	27027949	56836890	Rat
4889955	Bss93	Bone structure and strength QTL 93	4.4		tibia size trait (VT:0100001)	tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)	17	27027949	60463643	Rat
8552928	Pigfal9	Plasma insulin-like growth factor 1 level QTL 9	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	28409147	73409147	Rat
9590107	Sffal7	Serum free fatty acids level QTL 7	4.81	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	17	28409147	73409147	Rat
10450503	Bp386	Blood pressure QTL 386		0.28	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	31368391	62109574	Rat
2324621	Coatc5	Coat color QTL 5			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	17	31368391	73951021	Rat
724549	Niddm56	Non-insulin dependent diabetes mellitus QTL 56		0.03	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	31990784	76990784	Rat
1354663	Bvd5	Brain ventricular dilatation QTL 5	3.51	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	31990784	81292925	Rat
1300148	Bp192	Blood pressure QTL 192	3.47		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	17	34550843	73951021	Rat
724528	Uae4	Urinary albumin excretion QTL 4	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	17	35837085	69599340	Rat
2301412	Kidm40	Kidney mass QTL 40		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	37479847	82479847	Rat
2317054	Aia12	Adjuvant induced arthritis QTL 12	4.24		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	17	38281509	83281509	Rat
2317060	Aia26	Adjuvant induced arthritis QTL 26	3.22		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	38281509	83281509	Rat
1598871	Memor5	Memory QTL 5	5.3		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	17	40540041	80387013	Rat
1358295	Aocep1	Aortic cell protein QTL 1	6.1	0.00000071	thoracic aorta cellular protein amount (VT:0010598)	aortic cell percentage	17	40990005	85990005	Rat
631497	Bp98	Blood pressure QTL 98	3.66		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	41354651	60463643	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	17	42073160	69599340	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	42073160	69599340	Rat
7411575	Bw140	Body weight QTL 140	30.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	17	48560935	86533673	Rat
8694181	Bw151	Body weight QTL 151	4.36	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	17	48560935	86533673	Rat
2317038	Ginf3	Gastrointestinal inflammation QTL 3	2.89	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	17	49920154	86533673	Rat
2303580	Gluco49	Glucose level QTL 49	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	50040271	86533673	Rat
1354629	Scl31	Serum cholesterol level QTL 31	4.1		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	17	50890908	60781592	Rat
1354654	Spl7	Serum phospholipid level QTL 7	5.5		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	17	50890908	60781592	Rat
4889894	Eae33	Experimental allergic encephalomyelitis QTL 33	5.2	0.0001	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	50909099	86022412	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	50909196	60781426	Rat
1354588	Bvd4	Brain ventricular dilatation QTL 4	5.31	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	53498828	82479847	Rat
61466	Niddm12	Non-insulin dependent diabetes mellitus QTL 12	3.2	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	54029929	60463637	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	30	40	24	19	24	3	3	74	34	41	11	3
Low		13	17	17		17	5	8		1			5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001309462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003751704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063276006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005495222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC098858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000019968 ⟹ ENSRNOP00000019968

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	54,503,358 - 54,594,425 (-)	Ensembl
Rnor_6.0 Ensembl	17	57,304,933 - 57,394,985 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099548 ⟹ ENSRNOP00000085998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	54,565,066 - 54,567,707 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104942 ⟹ ENSRNOP00000086107

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	54,503,361 - 54,532,359 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117368 ⟹ ENSRNOP00000078400

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	54,503,361 - 54,566,580 (-)	Ensembl

RefSeq Acc Id:

NM_001309462 ⟹ NP_001296391

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,198,513 - 59,289,519 (-)	NCBI
mRatBN7.2	17	54,503,358 - 54,594,425 (-)	NCBI
Rnor_6.0	17	57,303,968 - 57,394,975 (-)	NCBI
Celera	17	50,484,141 - 50,575,159 (-)	NCBI

Sequence:

show sequence

ATTCCCCCCGACGCCCTCGGATCCTGCGGCTGCCCGCCCCGCTCCGCGCCCTCCATGGACGAAA
GTCTCACTTTTGATTTACCAAATATTTTCAGGATGTTTGAAGACCCGTACGCTGCCCGGAGGCT
GTTTTTTCTGGACAGCCCAGACCTCAGCCTATATTGTTACAATTTTTTTTTGAGAGCTAGCTGC
TGCTTTGCCTACACCGATGGAACACCATCTTCAGCGGGCTATCTCTGCACAGCAGGTGTACGGC
GAGAAGCGGGATAACATGGTTATTCCAGTTCCTGAAGCAGAAAGTAACATCGCTTACTATGAGT
CCATATACCCTGGGGAGTTCAAGATGCCAAAGCAGCTCATTCACATACAGCCTTTCAGCTTGGA
CGCTGAGCAGCCTGATTACGACCTGGATTCTGAGGATGAAGTCTTTGTGAATAAACTGAAGAAG
AAAATGGACATCTGCCCAGTGCAGTTTGAGGAGATGATTGACCGGTTAGAAAAAGGCAGCGGTC
AGCAGCCAGTCAGTCTGCAGGAAGCCAAACTACTTCTAAAAGAAGATGATGAGTTAATTAGAGA
AGTTTATGAATACTGGATTAAAAAGAGGAAAACCTGCCGGGGGCCATCACTTATCCCGTCGGTA
AAACAGGAAAAACGAGATGGTTCTAGCACAAATGATCCTTATGTGGCTTTTAGAAGACGAACTG
AGAAAATGCAAACTCGAAAAAATCGCAAAAACGATGAAGCCTCCTATGAGAAAATGCTTAAGCT
GCGCCGGGATCTCAGCCGGGCTGTCACCATCCTGGAGATGATCAAGAGACGTGAGAAAAGTAAA
CGGGAGCTGCTGCACCTGACACTGGAGATTATGGAGAAGAGGTATAATTTAGGTGACTACAGTG
GAGAGATCATGTCTGAGGTCATGGCACAGAGACAGCCAGTGAAGCCTACCTATGCCATCCCCAT
CATCCCGATTACTAACAGCAGCCAGTTCAAACACCAGGACGTCACGGATGCGAAGGAGTTCAAA
GTTAACAAGCAAGATAAGGCTGATCTTATTCGGCCGAAGCGCAAATATGAAAAGAAGCCCAAAG
TCTTACCGTCGTCTGCTGCCGCACCCCAGCAGCCAAGTCCTGCTGCACTGCCAGGCTTCAGTGC
TAAAGACTTAAACCAGTACGACTTCCCCAGCTCAGATGAAGAGCCTCTGTCACAGGTTTTGTCT
GGCTCTTCAGAAGCTGAGGAAGAGAATGACCCTGATGGCCCTTTCGCTTTCCGTAGGAAAGCAG
GCTGTCAGTACTATGCTCCTCATTTAGACCAAACTGGCAACTGGCCCTGGACTAGCCCTAAAGA
TGGAGGCCTGGGGGATGTGCGATATAGATATTGCTTAACTACTCTCACCGTACCCCAGAGGTGT
CTTGGATTTGCACGAAGACGGGTCGGGCGCGGTGGAAGGGTCTTGCTGGACAGAGCGCATTCAG
ACTATGACAGTATGTTTCACCACCTGGATCTGGACATGCTTTCCTCACCACAACCTTCTCCAGT
CAATCAGTTTGCCAATACCTCAGAAACCAATACCTCGGACAGACCTTCCTCTAAAGACCTCAGT
CAGATACTAGTCGATATCAAATCATGTAGATGGCGGCACTTTAGGCCCCGGACACCATCCCTTC
CTGACAGTGACAGTGGTGAGCTCTCCAGTAGAAAGTTACACAGAAGTATAAGTCGAGCAGGACC
AGCGCAGCCTGGGGCCCACACGTGCAGCGCCTCCACACAGAGCAGAAGTAGCAGTGGCTCGACA
CACTGTGCATTTACAGCCGAGCAGTACCAGCAGCACCAGCAGCAACTGGCACTCATGCAGCAGC
AGCAGCTTGCACAAACTCAGCAGCAGCAAGCAAATAGCAGTTCCTCCACCGCCGCTCCACAGGG
TTTTGTTTCTAAGACGTTGGATTCTGCCAGTGCACAGTTCGCTGCTTCTGCTTTAATGACGTCA
GAACAGCTGATGGGATTCAAGATGAAGGATGATGTGGTGCTTGGGATTGGGGTGAATGGCGTCC
TTCCCGCCTCAGGAGTATACAAGGGCTTGCACCTCAGCAGCACTACACCAACGGCGCTTGTACA
TACGAGTCCTTCGACCGCAGGTTCAACCTTGTTACAGCCTTCAAATATTACACAGACTTCGGGT
TCCCACAGCGCACTGAGTCACCAAGTAACTGCTGCCAACTCTGCAACAACTCAGGTTCTGTTTG
GGAACAACATCCGATTAACTGTCCCCTCATCTGTCCCCACTGTCAACTCTATCGCCCCAATAAA
CGCACGGCATATACCTAGGACTTTAAGTGCTGTTCCGCCATCTGCCTTAAAGCTGGCTGCTGCA
GCAAACTGTCAAGTTTCCAAGGTCCCCTCCTCATCCTCTGTAGATTCAGTTCCAAGGGAAAATC
ATGAATCAGAAAAGCCAGCACTGAACAACATAGCAGACAACACAGTAGCAATGGAGGTGACGTA
GCTTCCTGGGAGCAGGACTGCATCCTGGGGACATGGTCAGGTGCTATGCATCAGAGCGTTGGAA
CGCAGGGAGGATGGAGTGCGTAGGCGGTTCCGTGGCAGCTGTGGGGACTCGGCAGCACTGCGCA
CCTCTCGTGCTTCAACCTTTCTTTTCTTATTGTTAATAGGAAAAAATCAACATCTGTAAATTAA
GAATACAGCAATTATCTGTACAGTACTGCATATTTGTAATACCCTTGTATATATGTTACTTGAA
TACAGAACTGTTCATTTGTGATGCTTTGCACTTGGGGGCGGGGGGTGGGGGGTAACTGCAACAA
GAGTGTGAGCTGTGAGATTGTGTAGCTGGTGTCATCACATCATGTGCATGGTGCGGAACCTGCT
GTCTCTATTTATTGTGCCGTGTTTACAGGTTTTGTACACTGTACCCTCATTGGTTCCTGTGCTG
TAGTAAATGTGTTAGGTAGCTGTGGACTCCTTGGTATTTTGTAAATGGTATAACATAACTTGGT
TCCCTCTGGGTCCTTGAGTTTTCTGTGTATCATGTGAAAAAAAAAATGGTGACATACATACAGA
ATTTTACAAAAAAAAAAAAGGCATCAGTTTTTTAAAACGGGGAATGTACTGTTCAATGGGGATC
TTCCTGGTCTACTAGCATTAGGATGCGCAACAAGCTAAAAATGAAGTCTCTTGAATTCTCCCAT
CCCCGCCTGCCTGCAAGCTTGGGCAGCCCTGGTACTTAAAGCACTAATGTTATGTTGCTGCCCT
ACAAACAGCCCAGTCGTCCCATTTCCTTCCACACCAAAAAGTGTTAAATCAAGTACACAAACGG
AGTCCTTACAACTGGAGTTTATGTTGTCTTGCCCTTTTTTTAGCACAAAAAGATGTACTTTTAT
ATTGTGGAATTGTTTAAAGACTTCATTCTTTACTTGTTCTTACAGAAAGGATATAGGGGAGAAG
AATGCTGTCCGTGTATCGTCATTCCAGTTTGTAAAACAGCCAGCCAGCTTTTTCCTTTTAAGAT
TCTCCAGAAGGCTGCGAGGCCAGAACCACAAATATCGGGTGCCTTCCTTTGGAAATATTTGACC
TCTCTTCTGTGAAGAGAATGGTACTTACCAGACTACTACTGCTTTGTTAGTACCGAAGTCTGAA
TGCCCAGTCCAATGGCAGACATATGTTATCCTTAAGGTTTTTAATCCCACCTGGAAACATTGTG
ATAGAATTCTCACAAAATAAACCCAGGGCATTACATGTTGACAAACTAA

hide sequence

RefSeq Acc Id:

XM_003751704 ⟹ XP_003751752

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,198,513 - 59,261,863 (-)	NCBI
mRatBN7.2	17	54,503,358 - 54,566,651 (-)	NCBI
Rnor_6.0	17	57,303,968 - 57,367,178 (-)	NCBI
Rnor_5.0	17	55,332,012 - 55,423,030 (-)	NCBI

Sequence:

show sequence

AGCGAGTGAGCGAGGCGCGGAGCGGCACAGCCTCCCACCCTCCCGGCTGGTGTCAGGGCCCGGA
CGGCGGGCTTTGCGCTCCGCCCCCAAGTCCCCGGCAGCGGCAGGCGAGTGGAGACCGAAACTCC
GGTTCTCCATGATCCCGCTGGCCGGGGCCGTTTCCCCAGAGCGGAGAGGTATCTGCTGCGCCTG
AGATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTGGACGCCTCGAAGCCGCTGCCGGTCTTCCG
CTGTGAGGATCTGCCCGACCTGCACGAATACGCCTCGATAAACCGGGCCGTGCCGCAGATGCCC
ACCGGAATGGAGAAGGAAGAGGAGTCGGAACACCATCTTCAGCGGGCTATCTCTGCACAGCAGG
TGTACGGCGAGAAGCGGGATAACATGGTTATTCCAGTTCCTGAAGCAGAAAGTAACATCGCTTA
CTATGAGTCCATATACCCTGGGGAGTTCAAGATGCCAAAGCAGCTCATTCACATACAGCCTTTC
AGCTTGGACGCTGAGCAGCCTGATTACGACCTGGATTCTGAGGATGAAGTCTTTGTGAATAAAC
TGAAGAAGAAAATGGACATCTGCCCAGTGCAGTTTGAGGAGATGATTGACCGGTTAGAAAAAGG
CAGCGGTCAGCAGCCAGTCAGTCTGCAGGAAGCCAAACTACTTCTAAAAGAAGATGATGAGTTA
ATTAGAGAAGTTTATGAATACTGGATTAAAAAGAGGAAAACCTGCCGGGGGCCATCACTTATCC
CGTCGGTAAAACAGGAAAAACGAGATGGTTCTAGCACAAATGATCCTTATGTGGCTTTTAGAAG
ACGAACTGAGAAAATGCAAACTCGAAAAAATCGCAAAAACGATGAAGCCTCCTATGAGAAAATG
CTTAAGCTGCGCCGGGATCTCAGCCGGGCTGTCACCATCCTGGAGATGATCAAGAGACGTGAGA
AAAGTAAACGGGAGCTGCTGCACCTGACACTGGAGATTATGGAGAAGAGGTATAATTTAGGTGA
CTACAGTGGAGAGATCATGTCTGAGGTCATGGCACAGAGACAGCCAGTGAAGCCTACCTATGCC
ATCCCCATCATCCCGATTACTAACAGCAGCCAGTTCAAACACCAGGACGTCACGGATGCGAAGG
AGTTCAAAGTTAACAAGCAAGATAAGGCTGATCTTATTCGGCCGAAGCGCAAATATGAAAAGAA
GCCCAAAGTCTTACCGTCGTCTGCTGCCGCACCCCAGCAGCCAAGTCCTGCTGCACTGCCAGGC
TTCAGTGCTAAAGACTTAAACCAGTACGACTTCCCCAGCTCAGATGAAGAGCCTCTGTCACAGG
TTTTGTCTGGCTCTTCAGAAGCTGAGGAAGAGAATGACCCTGATGGCCCTTTCGCTTTCCGTAG
GAAAGCAGGCTGTCAGTACTATGCTCCTCATTTAGACCAAACTGGCAACTGGCCCTGGACTAGC
CCTAAAGATGGAGGCCTGGGGGATGTGCGATATAGATATTGCTTAACTACTCTCACCGTACCCC
AGAGGTGTCTTGGATTTGCACGAAGACGGGTCGGGCGCGGTGGAAGGGTCTTGCTGGACAGAGC
GCATTCAGACTATGACAGTATGTTTCACCACCTGGATCTGGACATGCTTTCCTCACCACAACCT
TCTCCAGTCAATCAGTTTGCCAATACCTCAGAAACCAATACCTCGGACAGACCTTCCTCTAAAG
ACCTCAGTCAGATACTAGTCGATATCAAATCATGTAGATGGCGGCACTTTAGGCCCCGGACACC
ATCCCTTCCTGACAGTGACAGTGGTGAGCTCTCCAGTAGAAAGTTACACAGAAGTATAAGTCGA
GCAGGACCAGCGCAGCCTGGGGCCCACACGTGCAGCGCCTCCACACAGAGCAGAAGTAGCAGTG
GCTCGACACACTGTGCATTTACAGCCGAGCAGTACCAGCAGCACCAGCAGCAACTGGCACTCAT
GCAGCAGCAGCAGCTTGCACAAACTCAGCAGCAGCAAGCAAATAGCAGTTCCTCCACCGCCGCT
CCACAGGGTTTTGTTTCTAAGACGTTGGATTCTGCCAGTGCACAGTTCGCTGCTTCTGCTTTAA
TGACGTCAGAACAGCTGATGGGATTCAAGATGAAGGATGATGTGGTGCTTGGGATTGGGGTGAA
TGGCGTCCTTCCCGCCTCAGGAGTATACAAGGGCTTGCACCTCAGCAGCACTACACCAACGGCG
CTTGTACATACGAGTCCTTCGACCGCAGGTTCAACCTTGTTACAGCCTTCAAATATTACACAGA
CTTCGGGTTCCCACAGCGCACTGAGTCACCAAGTAACTGCTGCCAACTCTGCAACAACTCAGGT
TCTGTTTGGGAACAACATCCGATTAACTGTCCCCTCATCTGTCCCCACTGTCAACTCTATCGCC
CCAATAAACGCACGGCATATACCTAGGACTTTAAGTGCTGTTCCGCCATCTGCCTTAAAGCTGG
CTGCTGCAGCAAACTGTCAAGTTTCCAAGGTCCCCTCCTCATCCTCTGTAGATTCAGTTCCAAG
GGAAAATCATGAATCAGAAAAGCCAGCACTGAACAACATAGCAGACAACACAGTAGCAATGGAG
GTGACGTAGCTTCCTGGGAGCAGGACTGCATCCTGGGGACATGGTCAGGTGCTATGCATCAGAG
CGTTGGAACGCAGGGAGGATGGAGTGCGTAGGCGGTTCCGTGGCAGCTGTGGGGACTCGGCAGC
ACTGCGCACCTCTCGTGCTTCAACCTTTCTTTTCTTATTGTTAATAGGAAAAAATCAACATCTG
TAAATTAAGAATACAGCAATTATCTGTACAGTACTGCATATTTGTAATACCCTTGTATATATGT
TACTTGAATACAGAACTGTTCATTTGTGATGCTTTGCACTTGGGGGCGGGGGGTGGGGGGTAAC
TGCAACAAGAGTGTGAGCTGTGAGATTGTGTAGCTGGTGTCATCACATCATGTGCATGGTGCGG
AACCTGCTGTCTCTATTTATTGTGCCGTGTTTACAGGTTTTGTACACTGTACCCTCATTGGTTC
CTGTGCTGTAGTAAATGTGTTAGGTAGCTGTGGACTCCTTGGTATTTTGTAAATGGTATAACAT
AACTTGGTTCCCTCTGGGTCCTTGAGTTTTCTGTGTATCATGTGAAAAAAAAAATGGTGACATA
CATACAGAATTTTACAAAAAAAAAAAAGGCATCAGTTTTTTAAAACGGGGAATGTACTGTTCAA
TGGGGATCTTCCTGGTCTACTAGCATTAGGATGCGCAACAAGCTAAAAATGAAGTCTCTTGAAT
TCTCCCATCCCCGCCTGCCTGCAAGCTTGGGCAGCCCTGGTACTTAAAGCACTAATGTTATGTT
GCTGCCCTACAAACAGCCCAGTCGTCCCATTTCCTTCCACACCAAAAAGTGTTAAATCAAGTAC
ACAAACGGAGTCCTTACAACTGGAGTTTATGTTGTCTTGCCCTTTTTTTAGCACAAAAAGATGT
ACTTTTATATTGTGGAATTGTTTAAAGACTTCATTCTTTACTTGTTCTTACAGAAAGGATATAG
GGGAGAAGAATGCTGTCCGTGTATCGTCATTCCAGTTTGTAAAACAGCCAGCCAGCTTTTTCCT
TTTAAGATTCTCCAGAAGGCTGCGAGGCCAGAACCACAAATATCGGGTGCCTTCCTTTGGAAAT
ATTTGACCTCTCTTCTGTGAAGAGAATGGTACTTACCAGACTACTACTGCTTTGTTAGTACCGA
AGTCTGAATGCCCAGTCCAATGGCAGACATATGTTATCCTTAAGGTTTTTAATCCCACCTGGAA
ACATTGTGATAGAATTCTCACAAAATAAACCCAGGGCATTACATGTTGACAAACTAA

hide sequence

RefSeq Acc Id:

XM_039095280 ⟹ XP_038951208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,198,513 - 59,261,753 (-)	NCBI
mRatBN7.2	17	54,503,358 - 54,569,408 (-)	NCBI

RefSeq Acc Id:

XM_039095281 ⟹ XP_038951209

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,198,513 - 59,289,535 (-)	NCBI
mRatBN7.2	17	54,503,358 - 54,594,444 (-)	NCBI

RefSeq Acc Id:

XM_063276006 ⟹ XP_063132076

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,198,513 - 59,261,762 (-)	NCBI

RefSeq Acc Id:

XR_005495222

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	59,204,344 - 59,261,753 (-)	NCBI
mRatBN7.2	17	54,509,189 - 54,566,656 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001296391	(Get FASTA)	NCBI Sequence Viewer
	XP_003751752	(Get FASTA)	NCBI Sequence Viewer
	XP_038951208	(Get FASTA)	NCBI Sequence Viewer
	XP_038951209	(Get FASTA)	NCBI Sequence Viewer
	XP_063132076	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98858	(Get FASTA)	NCBI Sequence Viewer
	EDL87472	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019968
	ENSRNOP00000019968.7
	ENSRNOP00000078400
	ENSRNOP00000078400.1
	ENSRNOP00000085998.1
	ENSRNOP00000086107.1

RefSeq Acc Id:	XP_003751752 ⟸ XM_003751704
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G2P8 (UniProtKB/TrEMBL), A0A8I6GEL3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQV YGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKL KKKMDICPVQFEEMIDRLEKGSGQQPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGPSLIP SVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREK SKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTYAIPIIPITNSSQFKHQDVTDAKE FKVNKQDKADLIRPKRKYEKKPKVLPSSAAAPQQPSPAALPGFSAKDLNQYDFPSSDEEPLSQV LSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKDGGLGDVRYRYCLTTLTVPQ RCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSETNTSDRPSSKD LSQILVDIKSCRWRHFRPRTPSLPDSDSGELSSRKLHRSISRAGPAQPGAHTCSASTQSRSSSG STHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQANSSSSTAAPQGFVSKTLDSASAQFAASALM TSEQLMGFKMKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQT SGSHSALSHQVTAANSATTQVLFGNNIRLTVPSSVPTVNSIAPINARHIPRTLSAVPPSALKLA AAANCQVSKVPSSSSVDSVPRENHESEKPALNNIADNTVAMEVT hide sequence

RefSeq Acc Id:

NP_001296391 ⟸ NM_001309462

- UniProtKB:

D4A6E4 (UniProtKB/TrEMBL), A6K9H9 (UniProtKB/TrEMBL), A0A8I6GEL3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPD
YDLDSEDEVFVNKLKKKMDICPVQFEEMIDRLEKGSGQQPVSLQEAKLLLKEDDELIREVYEYW
IKKRKTCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLS
RAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTYAIPIIPITN
SSQFKHQDVTDAKEFKVNKQDKADLIRPKRKYEKKPKVLPSSAAAPQQPSPAALPGFSAKDLNQ
YDFPSSDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKDGGLGD
VRYRYCLTTLTVPQRCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFAN
TSETNTSDRPSSKDLSQILVDIKSCRWRHFRPRTPSLPDSDSGELSSRKLHRSISRAGPAQPGA
HTCSASTQSRSSSGSTHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQANSSSSTAAPQGFVSKT
LDSASAQFAASALMTSEQLMGFKMKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPST
AGSTLLQPSNITQTSGSHSALSHQVTAANSATTQVLFGNNIRLTVPSSVPTVNSIAPINARHIP
RTLSAVPPSALKLAAAANCQVSKVPSSSSVDSVPRENHESEKPALNNIADNTVAMEVT

hide sequence

RefSeq Acc Id:

ENSRNOP00000019968 ⟸ ENSRNOT00000019968

RefSeq Acc Id:	XP_038951209 ⟸ XM_039095281
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GEL3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038951208 ⟸ XM_039095280
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GEL3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000078400 ⟸ ENSRNOT00000117368

RefSeq Acc Id:

ENSRNOP00000086107 ⟸ ENSRNOT00000104942

RefSeq Acc Id:

ENSRNOP00000085998 ⟸ ENSRNOT00000099548

RefSeq Acc Id:	XP_063132076 ⟸ XM_063276006
- Peptide Label:	isoform X4

Protein Domains

Enhancer of polycomb C-terminal Enhancer of polycomb-like N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A6E4-F1-model_v2	AlphaFold	D4A6E4	1-762	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700540

Promoter ID:

EPDNEW_R11055

Type:

initiation region

Name:

Epc1_1

Description:

enhancer of polycomb homolog 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	57,394,975 - 57,395,035	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2324280	AgrOrtholog
BioCyc Gene	G2FUF-8980	BioCyc
Ensembl Genes	ENSRNOG00000014834	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019968	ENTREZGENE
	ENSRNOT00000019968.8	UniProtKB/TrEMBL
	ENSRNOT00000099548.1	UniProtKB/TrEMBL
	ENSRNOT00000104942.1	UniProtKB/TrEMBL
	ENSRNOT00000117368.1	UniProtKB/TrEMBL
InterPro	Enhancer_polycomb	UniProtKB/TrEMBL
	Enhancer_polycomb-like_N	UniProtKB/TrEMBL
	Enhancer_polycomb_C	UniProtKB/TrEMBL
KEGG Report	rno:100362678	UniProtKB/TrEMBL
NCBI Gene	100362678	ENTREZGENE
PANTHER	ENHANCER OF POLYCOMB HOMOLOG 1	UniProtKB/TrEMBL
	PTHR14898	UniProtKB/TrEMBL
Pfam	E_Pc_C	UniProtKB/TrEMBL
	EPL1	UniProtKB/TrEMBL
PhenoGen	Epc1	PhenoGen
RatGTEx	ENSRNOG00000014834	RatGTEx
UniProt	A0A8I6A414_RAT	UniProtKB/TrEMBL
	A0A8I6G2P8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GEL3	ENTREZGENE, UniProtKB/TrEMBL
	A6K9H9	ENTREZGENE, UniProtKB/TrEMBL
	D4A6E4	ENTREZGENE, UniProtKB/TrEMBL
	Q4KM29_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Epc1	enhancer of polycomb homolog 1	Epc1	enhancer of polycomb homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-08-30	LOC100362678	enhancer of polycomb homolog 1	Epc1	enhancer of polycomb homolog 1 (Drosophila)	Data merged from RGD:1306027	737654	APPROVED
2012-08-30	Epc1	enhancer of polycomb homolog 1 (Drosophila)	LOC100362678	enhancer of polycomb homolog 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-06	LOC100362678	enhancer of polycomb homolog 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Epc1	enhancer of polycomb homolog 1 (Drosophila)	Epc1_predicted	enhancer of polycomb homolog 1 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Epc1_predicted	enhancer of polycomb homolog 1 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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