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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
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Accession:GO:1902175 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of intrinsic apoptotic signaling pathway in response to oxidative stress


show annotations for term's descendants           Sort by:
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12095988)
GO_REF:0000107		 HGNC
RGD
Ensembl		 PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA		 UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:5613479|PMID:14652021)		 RGD
Ensembl		 PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010)
(MGI:5574514|PMID:24947010)		 RGD PMID:24947010 MGI:5574514 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP		 (PMID:17579517) RGD PMID:17579517 PMID:17579517 RGD:8693356 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010)
UniProtKB:Q99497 (MGI:5574514|PMID:24947010)		 Ensembl
RGD		 PMID:24947010 GO_REF:0000107 MGI:5574514 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158814 (PMID:16373599)		 Ensembl
RGD		 PMID:16373599 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3581090|PMID:15731106)		 Ensembl
RGD		 PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12788088)		 GO_Central
RGD		 PMID:12788088 GO_REF:0000033 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA		 (PMID:15004034)
GO_REF:0000107		 RGD
Ensembl		 PMID:15004034 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093)
(MGI:5582151|PMID:22523093)		 RGD PMID:22523093 MGI:5582151 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:26095851)
GO_REF:0000024		 RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:17317627) RGD PMID:17317627 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
ISO		 PMID:23392669
UniProtKB:Q9ES19 (PMID:23392669)		 RGD PMID:23392669 PMID:23392669 RGD:10047168 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cpe carboxypeptidase E IMP RGD PMID:25426952 RGD:405650601 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5770063|PMID:21752258)		 Ensembl
RGD		 PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in		 ISO (PMID:26310625)
(PMID:25029497)		 RGD PMID:25029497 PMID:26310625 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:25426952 RGD:405650601 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5770063|PMID:21752258)		 Ensembl
RGD		 PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA		 (PMID:24899725)
GO_REF:0000107		 RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il10 interleukin 10 involved_in ISO ComplexPortal:CPX-1134 (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5575789|PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200)		 ParkinsonsUK-UCL
RGD		 PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 MGI:5575789 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
IEA
IGI		 (PMID:17314283)
GO_REF:0000024
(MGI:5543313|PMID:23858059)
GO_REF:0000107
PMID:23392669		 RGD
ParkinsonsUK-UCL
Ensembl		 PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107 MGI:5543313, RGD:10047168 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:5770063 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3616995 (PMID:19661248)		 Ensembl
RGD		 PMID:19661248 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA		 (PMID:12551919)
GO_REF:0000107		 RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:3052282 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 MGI:5543313 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) RGD PMID:15983381 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Prodh proline dehydrogenase involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6458378|PMID:30684126) RGD PMID:30684126 MGI:6458378 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      signal transduction 7020
        intracellular signal transduction 2744
          intrinsic apoptotic signaling pathway 338
            intrinsic apoptotic signaling pathway in response to oxidative stress 66
              regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 45
                negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 31
                positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 10
                regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
                regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway + 22
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13309
      regulation of biological process 12906
        signaling 7595
          signal transduction 7020
            intracellular signal transduction 2744
              intrinsic apoptotic signaling pathway 338
                intrinsic apoptotic signaling pathway in response to oxidative stress 66
                  regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 45
                    negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 31
                    positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 10
                    regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
                    regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway + 22
paths to the root