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ONTOLOGY REPORT - ANNOTATIONS

Term:response to acidic pH
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Accession:GO:0010447 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
Comment:This term should be used to annotate instances where a cell or organism is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0001101 'response to acid chemical'.
Synonyms:broad_synonym: response to acidity


show annotations for term's descendants           Sort by:
response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEP RGD PMID:19133233 RGD:2315756 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (PMID:11854527), (PMID:11988176) RGD PMID:11854527 PMID:11988176 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180111 (PMID:11306621), (PMID:11854527)		 Ensembl
RGD		 PMID:11306621 PMID:11854527 GO_REF:0000107 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 acts_upstream_of_or_within IDA
ISO		 PMID:9261094
MGI:2429689|MGI:2451051 (PMID:11754838), (PMID:11854527), (PMID:12060708)		 RGD PMID:11754838 PMID:11854527 PMID:12060708 PMID:9261094 RGD:1299543 NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643 		JBrowse link
G Ctss cathepsin S involved_in ISO
IEA		 (PMID:22864553)
GO_REF:0000107		 RGD
Ensembl		 PMID:22864553 GO_REF:0000107 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Gip gastric inhibitory polypeptide IMP HCl RGD PMID:34554 RGD:2312536 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gpr151 G protein-coupled receptor 151 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr18:34,568,907...34,570,301
Ensembl chr18:34,568,907...34,570,301 		JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr 1:52,926,953...52,927,912 JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:12955148), (PMID:17462861), (PMID:22110680)
MGI:3700206 (PMID:17145776)
GO_REF:0000024		 RGD
UniProt		 PMID:12955148 PMID:17145776 PMID:17462861 PMID:22110680 GO_REF:0000024 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:15618224) RGD PMID:15618224 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Lgmn legumain involved_in
acts_upstream_of_or_within		 ISO (PMID:18374643)
MGI:2676125 (PMID:18374643)
(MGI:5702834|PMID:25326800)
(PMID:9065484)		 RGD PMID:9065484 PMID:18374643 PMID:25326800 MGI:5702834 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP HCl RGD PMID:7729276 RGD:2317551 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Serpinf1 serpin family F member 1 IEP RGD PMID:19575033 RGD:8554877 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in
acts_upstream_of_or_within		 IDA
ISO
ISS		 PMID:18321853
MGI:2429323 (PMID:10673550)
(PMID:8901634)
GO_REF:0000024		 RGD
UniProt		 PMID:8901634 PMID:10673550 PMID:18321853 GO_REF:0000024, RGD:8554433 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12081562 RGD:634206 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sst somatostatin IEP HCl RGD PMID:18992283 RGD:2303157 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IEP RGD PMID:15240346 RGD:2312428 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
cellular response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp10 aquaporin 10 involved_in ISO (PMID:30420639) RGD PMID:30420639 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IEP RGD PMID:26033523 RGD:13204712 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:8458414 RGD:7243874 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting involved_in
NOT|involved_in		 ISO (MGI:5315344|PMID:16891422)
(MGI:4888566|PMID:20605874)		 RGD PMID:16891422 PMID:20605874 MGI:4888566 MGI:5315344 NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (MGI:5315344|PMID:16891422), (MGI:6149416|PMID:29567962) RGD PMID:16891422 PMID:29567962 MGI:5315344 MGI:6149416 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO
ISS		 (PMID:20717956)
GO_REF:0000024		 RGD
UniProt		 PMID:20717956 GO_REF:0000024 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:20717956) RGD PMID:20717956 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24840010)		 UniProt
RGD		 PMID:24840010 GO_REF:0000024 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA		 (PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
cellular stress response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10515
      response to abiotic stimulus 1578
        response to pH 57
          response to acidic pH 31
            cellular response to acidic pH + 15
paths to the root