Gene: Scnn1b (sodium channel epithelial 1 beta subunit) Rattus norvegicus
Symbol: Scnn1b
Name: sodium channel epithelial 1 beta subunit
Description: ENCODES a protein that exhibits ligand-gated sodium channel activity; WW domain binding; sodium channel activity (ortholog); INVOLVED IN regulation of sodium ion transport; response to hypoxia; sodium ion transmembrane transport; PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Nephrotic Syndrome; Adrenal Insufficiency (ortholog); Bronchiectasis (ortholog); FOUND IN apical plasma membrane; cell surface; external side of plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amiloride-sensitive sodium channel subunit beta; beta-ENaC; beta-NaCH; epithelial Na(+) channel subunit beta; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; Sodium channel nonvoltage-gated 1 beta (epithelial); sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, nonvoltage-gated, type I, beta
Orthologs:
Is Marker For: Strains:   SHR.BN-(D1Mit3-Igf2)/Ipcv  
QTLs:   Bp88  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01191,829,552 - 191,883,991 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01198,932,512 - 198,953,453 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41180,682,622 - 180,748,068 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,822,536 - 180,887,983 (+)NCBI
Celera1174,140,255 - 174,194,462 (+)NCBI
Cytogenetic Map1q36-q41NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scnn1b
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3640
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-04-12
Status: ACTIVE