Gene: Scnn1b (sodium channel, non-voltage-gated 1, beta subunit) Rattus norvegicus
Symbol: Scnn1b
Name: sodium channel, non-voltage-gated 1, beta subunit
Description: ENCODES a protein that exhibits ligand-gated sodium channel activity; WW domain binding; sodium channel activity (ortholog); INVOLVED IN regulation of sodium ion transport; response to hypoxia; sodium ion transmembrane transport; PARTICIPATES IN aldosterone signaling pathway; ASSOCIATED WITH Nephrotic Syndrome; Adrenal Insufficiency (ortholog); Alkalosis (ortholog); FOUND IN apical plasma membrane; cell surface; external side of plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amiloride-sensitive sodium channel subunit beta; beta-ENaC; beta-NaCH; epithelial Na(+) channel subunit beta; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; Sodium channel nonvoltage-gated 1 beta (epithelial); sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, nonvoltage-gated, type I, beta
Orthologs:
Is Marker For: QTLs:   Bp88  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map1q36-q41 NCBI
RGSC Genome Assembly v5.01198,932,512 - 198,953,453-NCBI
RGSC Genome Assembly v3.41180,682,622 - 180,748,068+NCBI
Rat Celera Assembly1174,140,255 - 174,194,462+NCBI
Genome Assembly 3.11180,822,536 - 180,887,983+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scnn1b
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RGD Object Information
RGD ID: 3640
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-08-12
Status: ACTIVE