Gene: Acan (aggrecan) Rattus norvegicus
Symbol: Acan
Name: aggrecan
Description: ENCODES a protein that exhibits calcium ion binding; INVOLVED IN cellular response to growth factor stimulus; central nervous system development; chondroblast differentiation; ASSOCIATED WITH Brain Injuries; Spinal Cord Injuries; Tendon Injuries; FOUND IN perineuronal net; proteinaceous extracellular matrix; basement membrane (ortholog); INTERACTS WITH (R)-mevalonic acid; 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine
Type: protein-coding
Also known as: Agc; Agc1; aggrecan 1; aggrecan core protein; aggrecan structural proteoglycan of cartilage; aggrecan, structural proteoglycan of cartilage; cartilage-specific proteoglycan core protein; CSPCP
Homo sapiens : ACAN (aggrecan)  HGNC
Mus musculus : Acan (aggrecan)  MGI
more info ...
Latest Assembly: RGSC Genome Assembly v3.4
RGSC Genome Assembly v6.01140,762,758 - 140,824,441+NCBI
Rat Cytogenetic Map1q31 NCBI
RGSC Genome Assembly v5.01141,732,130 - 141,793,202+NCBI
RGSC Genome Assembly v3.41134,787,341 - 134,848,992+NCBI
Rat Celera Assembly1125,052,984 - 125,114,449+NCBI
Genome Assembly 3.11134,865,683 - 134,927,335+NCBI

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Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acan
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 68358
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2014-10-21
Status: ACTIVE