Sptan1 (spectrin alpha, non-erythrocytic 1) - Rat Genome Database

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Gene: Sptan1 (spectrin alpha, non-erythrocytic 1) Chinchilla lanigera
Analyze
Symbol: Sptan1
Name: spectrin alpha, non-erythrocytic 1
RGD ID: 9036605
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); spectrin binding (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant distal hereditary motor neuronopathy 11 (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN cortical cytoskeleton (ortholog); cuticular plate (ortholog); fascia adherens (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fodrin; spectrin alpha chain, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBIChiLan1.0ChiLan1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sptan1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBIChiLan1.0ChiLan1.0
SPTAN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,552,587 - 128,633,662 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,552,558 - 128,633,663 (+)Ensemblhg38GRCh38
GRCh379131,314,866 - 131,395,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,354,687 - 130,435,762 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349128,394,439 - 128,475,426NCBI
Celera9101,965,660 - 102,046,740 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,926,750 - 101,007,765 (+)NCBIHuRef
CHM1_19131,465,810 - 131,546,871 (+)NCBICHM1_1
T2T-CHM13v2.09140,759,427 - 140,840,530 (+)NCBIT2T-CHM13v2.0
Sptan1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,855,572 - 29,921,463 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl229,855,572 - 29,921,463 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38229,965,560 - 30,031,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl229,965,560 - 30,031,451 (+)Ensemblmm10GRCm38
MGSCv37229,821,080 - 29,886,971 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36229,787,569 - 29,853,460 (+)NCBIMGSCv36mm8
Celera229,669,500 - 29,735,203 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map220.93NCBI
Sptan1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,639,020 - 33,703,890 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl333,607,210 - 33,703,889 (+)EnsemblGRCr8
mRatBN7.2313,241,164 - 13,306,047 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,241,217 - 13,306,046 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,315,861 - 16,380,393 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0324,900,818 - 24,965,352 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,151,547 - 23,216,077 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd331,196,614 - 31,261,199 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive338,153,319 - 38,218,102 (+)NCBILyon_Normotensive
Lyon_Hypertensive330,052,322 - 30,117,105 (+)NCBILyon_Hypertensive
F344_StmMcwi311,252,639 - 11,317,423 (+)NCBIF344_StmMcwi
Rnor_6.038,534,437 - 8,599,259 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,534,440 - 8,599,260 (+)Ensemblrn6Rnor6.0
Rnor_5.0313,878,433 - 13,950,970 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.438,956,380 - 9,021,831 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,018,277 - 8,083,081 (+)NCBICelera
RGSC_v3.138,956,679 - 9,022,131 (+)NCBI
Cytogenetic Map3p12NCBI
SPTAN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,718,343 - 10,799,503 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,720,693 - 10,801,863 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,674,819 - 99,755,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,341,739 - 128,422,971 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,341,739 - 128,422,971 (+)EnsemblpanPan2panpan1.1
SPTAN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,953,751 - 55,015,475 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,953,747 - 55,015,376 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha954,149,445 - 54,211,133 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0955,876,077 - 55,937,766 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,876,080 - 55,937,760 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,635,563 - 54,694,357 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,949,366 - 55,011,369 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,041,985 - 55,103,647 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sptan1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,302,505 - 196,374,135 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,070,996 - 16,142,662 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,071,043 - 16,142,662 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPTAN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,936,025 - 269,002,256 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11268,936,120 - 269,002,261 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,959,613 - 303,025,990 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPTAN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,503,752 - 9,585,297 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,503,367 - 9,585,268 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660796,662,808 - 6,746,597 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sptan1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,331,554 - 6,386,216 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247606,331,554 - 6,388,953 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sptan1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v156,701,511 - 6,766,710 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000001487   ⟹   ENSCLAP00000001444
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001488   ⟹   ENSCLAP00000001445
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001489   ⟹   ENSCLAP00000001446
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001490   ⟹   ENSCLAP00000001447
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001491   ⟹   ENSCLAP00000001448
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555701,027,852 - 1,076,212 (+)Ensembl
RefSeq Acc Id: XM_005413564   ⟹   XP_005413621
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005413568   ⟹   XP_005413625
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005413569   ⟹   XP_005413626
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005413572   ⟹   XP_005413629
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005413573   ⟹   XP_005413630
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509402   ⟹   XP_013364856
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509403   ⟹   XP_013364857
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509404   ⟹   XP_013364858
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005413621   ⟸   XM_005413564
- Peptide Label: isoform X1
- UniProtKB: A0A8C2ULC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005413625   ⟸   XM_005413568
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UIJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005413626   ⟸   XM_005413569
- Peptide Label: isoform X5
- UniProtKB: A0A8C2UIJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005413629   ⟸   XM_005413572
- Peptide Label: isoform X7
- UniProtKB: A0A8C2UIJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005413630   ⟸   XM_005413573
- Peptide Label: isoform X8
- UniProtKB: A0A8C2UIJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364858   ⟸   XM_013509404
- Peptide Label: isoform X6
- UniProtKB: A0A8C2UIJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364856   ⟸   XM_013509402
- Peptide Label: isoform X2
- UniProtKB: A0A8C2ULC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364857   ⟸   XM_013509403
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UNG3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000001445   ⟸   ENSCLAT00000001488
Ensembl Acc Id: ENSCLAP00000001444   ⟸   ENSCLAT00000001487
Ensembl Acc Id: ENSCLAP00000001446   ⟸   ENSCLAT00000001489
Ensembl Acc Id: ENSCLAP00000001448   ⟸   ENSCLAT00000001491
Ensembl Acc Id: ENSCLAP00000001447   ⟸   ENSCLAT00000001490
Protein Domains
EF-hand   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001091 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001487 ENTREZGENE
  ENSCLAT00000001487.1 UniProtKB/TrEMBL
  ENSCLAT00000001488 ENTREZGENE
  ENSCLAT00000001488.1 UniProtKB/TrEMBL
  ENSCLAT00000001489 ENTREZGENE
  ENSCLAT00000001489.1 UniProtKB/TrEMBL
  ENSCLAT00000001490 ENTREZGENE
  ENSCLAT00000001490.1 UniProtKB/TrEMBL
  ENSCLAT00000001491 ENTREZGENE
  ENSCLAT00000001491.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  1.20.58.60 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Alpha_Spectrin_SH3 UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF-hand_Ca_insen UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
NCBI Gene Sptan1 ENTREZGENE
PANTHER SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  EFhand_Ca_insen UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
  Spectrin UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
  SPECTRNALPHA UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  efhand_Ca_insen UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
Superfamily-SCOP Spectrin repeat UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A8C2UIJ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UIJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UKL7_CHILA UniProtKB/TrEMBL
  A0A8C2ULC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UNG3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Sptan1  spectrin alpha, non-erythrocytic 1    spectrin, alpha, non-erythrocytic 1  Symbol and/or name change 5135510 APPROVED