Uxs1 (UDP-glucuronate decarboxylase 1) - Rat Genome Database

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Gene: Uxs1 (UDP-glucuronate decarboxylase 1) Rattus norvegicus
Analyze
Symbol: Uxs1
Name: UDP-glucuronate decarboxylase 1
RGD ID: 628680
Description: Enables UDP-glucuronate decarboxylase activity. Predicted to be involved in UDP-D-xylose biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be part of catalytic complex. Predicted to be active in cytoplasm. Orthologous to human UXS1 (UDP-glucuronate decarboxylase 1); PARTICIPATES IN galactokinase deficiency pathway; GALE deficiency pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93157; UDP-glucuronic acid decarboxylase 1; UGD; UXS-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89740,929 - 818,310 (+)NCBIGRCr8
mRatBN7.29653,740 - 731,121 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9653,659 - 756,334 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,101,032 - 1,178,186 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,448,086 - 6,525,417 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,338,604 - 5,415,805 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,165,006 - 11,240,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,164,715 - 11,339,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,150,134 - 10,226,955 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,775,435 - 7,852,399 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization. Moriarity JL, etal., J Biol Chem 2002 May 10;277(19):16968-75.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:18614015   PMID:19199708   PMID:23072385   PMID:23656592  


Genomics

Comparative Map Data
Uxs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89740,929 - 818,310 (+)NCBIGRCr8
mRatBN7.29653,740 - 731,121 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9653,659 - 756,334 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,101,032 - 1,178,186 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,448,086 - 6,525,417 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,338,604 - 5,415,805 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,165,006 - 11,240,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,164,715 - 11,339,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,150,134 - 10,226,955 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,775,435 - 7,852,399 (-)NCBICelera
Cytogenetic Map9q11NCBI
UXS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382106,093,311 - 106,194,301 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2106,093,308 - 106,194,301 (-)EnsemblGRCh38hg38GRCh38
GRCh372106,709,767 - 106,810,757 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362106,076,191 - 106,177,227 (-)NCBINCBI36Build 36hg18NCBI36
Build 342106,168,277 - 106,269,313NCBI
Celera2100,910,185 - 101,011,254 (-)NCBICelera
Cytogenetic Map2q12.2NCBI
HuRef2100,479,737 - 100,580,558 (-)NCBIHuRef
CHM1_12106,714,842 - 106,815,643 (-)NCBICHM1_1
T2T-CHM13v2.02106,554,193 - 106,655,255 (-)NCBIT2T-CHM13v2.0
Uxs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,786,121 - 43,866,999 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,786,126 - 43,866,960 (-)EnsemblGRCm39 Ensembl
GRCm38143,746,961 - 43,827,839 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl143,746,966 - 43,827,800 (-)EnsemblGRCm38mm10GRCm38
MGSCv37143,807,076 - 43,884,553 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36143,693,833 - 43,772,294 (-)NCBIMGSCv36mm8
Celera144,100,573 - 44,177,690 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map123.46NCBI
Uxs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547010,659,520 - 10,706,269 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547010,661,210 - 10,706,504 (-)NCBIChiLan1.0ChiLan1.0
UXS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,539,772 - 21,658,545 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A21,542,537 - 21,660,161 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A95,652,107 - 95,770,022 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A107,168,081 - 107,234,626 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A107,168,309 - 107,234,632 (-)Ensemblpanpan1.1panPan2
UXS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11037,342,675 - 37,407,725 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1037,342,746 - 37,407,252 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1037,238,647 - 37,332,207 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01038,164,639 - 38,257,518 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1038,164,685 - 38,257,471 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11037,896,777 - 37,989,649 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01038,173,540 - 38,266,403 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01038,367,280 - 38,460,904 (+)NCBIUU_Cfam_GSD_1.0
Uxs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,409,779 - 92,504,443 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367294,916 - 99,818 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367295,056 - 99,755 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UXS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl348,870,948 - 48,940,721 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1348,871,036 - 48,940,736 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2351,082,501 - 51,149,409 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UXS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1149,692,449 - 9,808,837 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl149,713,123 - 9,808,764 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041177,415,766 - 177,532,870 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uxs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247499,969,492 - 10,021,913 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247499,969,500 - 10,021,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uxs1
93 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:74
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000070920
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 41 28 19 28 2 74 31 40 11
Low 8 16 13 13 8 9 4 1 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_139336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF482705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000070920   ⟹   ENSRNOP00000066044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,756 - 731,117 (+)Ensembl
Rnor_6.0 Ensembl911,165,011 - 11,240,282 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082837   ⟹   ENSRNOP00000070855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,816 - 731,665 (+)Ensembl
Rnor_6.0 Ensembl911,164,715 - 11,339,790 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094164   ⟹   ENSRNOP00000094146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,659 - 731,665 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097842   ⟹   ENSRNOP00000081667
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,786 - 731,004 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098406   ⟹   ENSRNOP00000076956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,788 - 731,114 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100774   ⟹   ENSRNOP00000090850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,661 - 731,665 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103355   ⟹   ENSRNOP00000091666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9686,770 - 756,334 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109679   ⟹   ENSRNOP00000090204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,785 - 731,103 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119230   ⟹   ENSRNOP00000095660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9653,776 - 731,026 (+)Ensembl
RefSeq Acc Id: NM_139336   ⟹   NP_647552
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 818,310 (+)NCBI
mRatBN7.29653,792 - 731,117 (+)NCBI
Rnor_6.0911,165,010 - 11,240,270 (-)NCBI
Rnor_5.0910,150,134 - 10,226,955 (-)NCBI
Celera97,775,435 - 7,852,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244296   ⟹   XP_006244358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,932 - 818,310 (+)NCBI
mRatBN7.29653,741 - 731,117 (+)NCBI
Rnor_6.0911,165,006 - 11,240,329 (-)NCBI
Rnor_5.0910,150,134 - 10,226,955 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766751   ⟹   XP_008764973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 818,310 (+)NCBI
mRatBN7.29653,792 - 731,117 (+)NCBI
Rnor_6.0911,165,006 - 11,240,217 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596271   ⟹   XP_017451760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 818,310 (+)NCBI
mRatBN7.29653,792 - 731,117 (+)NCBI
Rnor_6.0911,165,006 - 11,240,217 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596272   ⟹   XP_017451761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 818,310 (+)NCBI
mRatBN7.29653,792 - 730,419 (+)NCBI
Rnor_6.0911,165,006 - 11,240,217 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596274   ⟹   XP_017451763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,954 - 818,310 (+)NCBI
mRatBN7.29653,911 - 731,121 (+)NCBI
Rnor_6.0911,165,006 - 11,240,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083019   ⟹   XP_038938947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 818,310 (+)NCBI
mRatBN7.29653,792 - 730,419 (+)NCBI
RefSeq Acc Id: XM_039083022   ⟹   XP_038938950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,934 - 818,310 (+)NCBI
mRatBN7.29653,740 - 731,121 (+)NCBI
RefSeq Acc Id: XM_039083023   ⟹   XP_038938951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,934 - 818,310 (+)NCBI
mRatBN7.29653,742 - 731,117 (+)NCBI
RefSeq Acc Id: XM_063266634   ⟹   XP_063122704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266635   ⟹   XP_063122705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,930 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266636   ⟹   XP_063122706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,931 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266638   ⟹   XP_063122708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266639   ⟹   XP_063122709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,980 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266640   ⟹   XP_063122710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89741,097 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266641   ⟹   XP_063122711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,984 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266642   ⟹   XP_063122712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,929 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266644   ⟹   XP_063122714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89765,700 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266645   ⟹   XP_063122715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,931 - 804,359 (+)NCBI
RefSeq Acc Id: XM_063266646   ⟹   XP_063122716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89740,930 - 804,359 (+)NCBI
Protein Sequences
Protein RefSeqs NP_647552 (Get FASTA)   NCBI Sequence Viewer  
  XP_006244358 (Get FASTA)   NCBI Sequence Viewer  
  XP_008764973 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451760 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451761 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451763 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938947 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938950 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938951 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122704 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122705 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122706 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122708 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122709 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122710 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122711 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122712 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122714 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122715 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122716 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86988 (Get FASTA)   NCBI Sequence Viewer  
  AAM45939 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066044.3
  ENSRNOP00000070855
  ENSRNOP00000070855.2
  ENSRNOP00000076956.1
  ENSRNOP00000081667.1
  ENSRNOP00000090204.1
  ENSRNOP00000090850.1
  ENSRNOP00000091666.1
  ENSRNOP00000094146
  ENSRNOP00000094146.1
  ENSRNOP00000095660.1
GenBank Protein Q5PQX0 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_647552   ⟸   NM_139336
- UniProtKB: Q5PQX0 (UniProtKB/Swiss-Prot),   Q8K464 (UniProtKB/Swiss-Prot),   A6KR28 (UniProtKB/TrEMBL),   A0A8I6AAA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244358   ⟸   XM_006244296
- Peptide Label: isoform X8
- UniProtKB: A0A8L2R317 (UniProtKB/TrEMBL),   A0A8I6AAA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764973   ⟸   XM_008766751
- Peptide Label: isoform X4
- UniProtKB: A0A8L2QX18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451761   ⟸   XM_017596272
- Peptide Label: isoform X11
- UniProtKB: A0A8L2QX18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451760   ⟸   XM_017596271
- Peptide Label: isoform X10
- UniProtKB: A0A8I6AIX5 (UniProtKB/TrEMBL),   A0A8L2QX18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451763   ⟸   XM_017596274
- Peptide Label: isoform X14
- UniProtKB: A0A8L2QX18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066044   ⟸   ENSRNOT00000070920
RefSeq Acc Id: ENSRNOP00000070855   ⟸   ENSRNOT00000082837
RefSeq Acc Id: XP_038938950   ⟸   XM_039083022
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038938951   ⟸   XM_039083023
- Peptide Label: isoform X14
- UniProtKB: A0A8L2QX18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938947   ⟸   XM_039083019
- Peptide Label: isoform X5
- UniProtKB: A0A8L2QX18 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000076956   ⟸   ENSRNOT00000098406
RefSeq Acc Id: ENSRNOP00000091666   ⟸   ENSRNOT00000103355
RefSeq Acc Id: ENSRNOP00000094146   ⟸   ENSRNOT00000094164
RefSeq Acc Id: ENSRNOP00000090850   ⟸   ENSRNOT00000100774
RefSeq Acc Id: ENSRNOP00000090204   ⟸   ENSRNOT00000109679
RefSeq Acc Id: ENSRNOP00000095660   ⟸   ENSRNOT00000119230
RefSeq Acc Id: ENSRNOP00000081667   ⟸   ENSRNOT00000097842
RefSeq Acc Id: XP_063122712   ⟸   XM_063266642
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063122705   ⟸   XM_063266635
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063122716   ⟸   XM_063266646
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063122706   ⟸   XM_063266636
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063122715   ⟸   XM_063266645
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063122704   ⟸   XM_063266634
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122708   ⟸   XM_063266638
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063122709   ⟸   XM_063266639
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122711   ⟸   XM_063266641
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063122710   ⟸   XM_063266640
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063122714   ⟸   XM_063266644
- Peptide Label: isoform X16
Protein Domains
NAD(P)-binding   UDP-glucuronate decarboxylase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PQX0-F1-model_v2 AlphaFold Q5PQX0 1-420 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696478
Promoter ID:EPDNEW_R7002
Type:initiation region
Name:Uxs1_2
Description:UDP-glucuronate decarboxylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7003  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0911,240,276 - 11,240,336EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628680 AgrOrtholog
BioCyc Gene G2FUF-28579 BioCyc
BioCyc Pathway PWY-4821 [UDP-alpha-D-xylose biosynthesis] BioCyc
BioCyc Pathway Image PWY-4821 BioCyc
Ensembl Genes ENSRNOG00000045605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070920.3 UniProtKB/TrEMBL
  ENSRNOT00000082837.2 UniProtKB/TrEMBL
  ENSRNOT00000094164 ENTREZGENE
  ENSRNOT00000094164.1 UniProtKB/TrEMBL
  ENSRNOT00000097842.1 UniProtKB/TrEMBL
  ENSRNOT00000098406.1 UniProtKB/TrEMBL
  ENSRNOT00000100774.1 UniProtKB/TrEMBL
  ENSRNOT00000103355.1 UniProtKB/TrEMBL
  ENSRNOT00000109679.1 UniProtKB/TrEMBL
  ENSRNOT00000119230.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-galactose 4-epimerase, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192831 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UXS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UXS1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:246232 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93157 IMAGE-MGC_LOAD
NCBI Gene 246232 ENTREZGENE
PANTHER PTHR43078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-GLUCURONIC ACID DECARBOXYLASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GDP_Man_Dehyd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UXS1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uxs1 PhenoGen
RatGTEx ENSRNOG00000045605 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y6P5_RAT UniProtKB/TrEMBL
  A0A8I6AAA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APA4_RAT UniProtKB/TrEMBL
  A0A8I6G6A9_RAT UniProtKB/TrEMBL
  A0A8I6GJ55_RAT UniProtKB/TrEMBL
  A0A8I6GJ72_RAT UniProtKB/TrEMBL
  A0A8L2QX18 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R317 ENTREZGENE, UniProtKB/TrEMBL
  A6KR28 ENTREZGENE, UniProtKB/TrEMBL
  A6KR29_RAT UniProtKB/TrEMBL
  Q5PQX0 ENTREZGENE
  Q8K464 ENTREZGENE
  UXS1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q8K464 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Uxs1  UDP-glucuronate decarboxylase 1      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Uxs1  UDP-glucuronate decarboxylase 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the perinuclear Golgi 625412